YEATS2
Homo sapiens
Gene Name: YEATS domain containing 2
Aliases:
Chromosome No: 3
Chromosome Band: 3q27.1
Genetic Category: Genetic association-Rare single gene variant
Aliases:
Chromosome No: 3
Chromosome Band: 3q27.1
Genetic Category: Genetic association-Rare single gene variant
Summary Statistics:
ASD Reports: 4
Recent Reports: 0
Annotated variants: 7
Associated CNVs: 8
Evidence score: 3
ASD Reports: 4
Recent Reports: 0
Annotated variants: 7
Associated CNVs: 8
Evidence score: 3
| Associated Disorders: |
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Relevance to Autism
A SNP within the YEATS2 gene showed association in the secondary analyses in a combined AGP GWA sample (Anney et al., 2012).
Molecular Function
YEATS2 is a scaffolding subunit of the ADA2A (TADA2A; MIM 602276)-containing (ATAC) histone acetyltransferase complex.
External Links
References
Type
Title
Type of Disorder
Associated Disorders
Author, Year
Primary
Individual common variants exert weak effects on the risk for autism spectrum disorderspi.
ASD
Support
Inherited and De Novo Genetic Risk for Autism Impacts Shared Networks.
ASD
Rare
Variant ID
Variant Type
Allele Change
Residue Change
Inheritance Pattern
Inheritance Association
Family Type
Author, Year
GEN397R001
frameshift_variant
c.3686_3687dup
p.Cys1230GlyfsTer15
Familial
Paternal
Multiplex
GEN397R006
frameshift_variant
c.3171del
p.Lys1057AsnfsTer5
Familial
Paternal
Multiplex
Common
Variant ID
Polymorphism
SNP ID
Allele Change
Residue Change
Population Origin
Population Stage
Author, Year
GEN397C001
intron_variant
rs263035
c.3785-997A>G;c.3788-997A>G
Autism Genome Project (AGP)
Combined (Stages 1 and 2)
