RHOXF1
Homo sapiens
Gene Name: Rhox homeobox family, member 1
Aliases: OTEX, PEPP1
Chromosome No: X
Chromosome Band: Xq24
Genetic Category: Genetic Association
Aliases: OTEX, PEPP1
Chromosome No: X
Chromosome Band: Xq24
Genetic Category: Genetic Association
Summary Statistics:
ASD Reports: 3
Recent Reports: 0
Annotated variants: 2
Associated CNVs: 10
Evidence score: null
ASD Reports: 3
Recent Reports: 0
Annotated variants: 2
Associated CNVs: 10
Evidence score: null
| Associated Disorders: |
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Relevance to Autism
Genetic association has been found between the RHOXF1 gene and autism in two large cohorts (AGRE and ACC) of European ancestry and replicated in two other cohorts (CAP and CART) (Wang et al., 2009).
Molecular Function
May be a transcription factor involved in reproductive processes.
External Links
References
Type
Title
Type of Disorder
Associated Disorders
Author, Year
Primary
Common genetic variants on 5p14.1 associate with autism spectrum disorders.
ASD
Positive Association
A genome-wide association study of autism incorporating autism diagnostic interview-revised, autism diagnostic observation schedule, and social res...
ASD
Highly Cited
OTEX, an androgen-regulated human member of the paired-like class of homeobox genes.
