OR2M4
Homo sapiens
Gene Name: Olfactory receptor, family 2, subfamily M, member 4
Aliases: HSHTPCRX18, HTPCRX18, OR1-55, OST710, TPCR100
Chromosome No: 1
Chromosome Band: 1q44
Genetic Category: Genetic association
Aliases: HSHTPCRX18, HTPCRX18, OR1-55, OST710, TPCR100
Chromosome No: 1
Chromosome Band: 1q44
Genetic Category: Genetic association
Summary Statistics:
ASD Reports: 1
Recent Reports: 0
Annotated variants: 4
Associated CNVs: 9
Evidence score: null
ASD Reports: 1
Recent Reports: 0
Annotated variants: 4
Associated CNVs: 9
Evidence score: null
| Associated Disorders: |
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Relevance to Autism
A total of four SNPs within 100 kb of the OR2M4 gene showed association with ASD in a case-control analysis in the Taiwanese Han population (Kuo et al., 2015).
Molecular Function
This gene encodes an olfactory receptor, which interacts with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell.
External Links
References
Type
Title
Type of Disorder
Associated Disorders
Author, Year
Primary
Genome-Wide Association Study for Autism Spectrum Disorder in Taiwanese Han Population.
ASD
Rare
No Rare Variants Available
Common
Variant ID
Polymorphism
SNP ID
Allele Change
Residue Change
Population Origin
Population Stage
Author, Year
GEN776C001
intergenic_variant
rs10888329
315 ASD cases, 1115 healthy controls (Taiwanese Han)
Discovery
GEN776C002
intergenic_variant
rs6672981
315 ASD cases, 1115 healthy controls (Taiwanese Han)
Discovery
GEN776C003
intergenic_variant
rs4642918
315 ASD cases, 1115 healthy controls (Taiwanese Han)
Discovery
GEN776C004
intergenic_variant
rs4397683
315 ASD cases, 1115 healthy controls (Taiwanese Han)
Discovery