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construct
Z_NBEA_4_MOSAIC_WT_NBEA_PRESYNM
Model Details
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Phenotypic Profile
Category Entity Quantity Experimental Paradigm Age at Testing
Neuroanatomy / Ultrastructure / Cytoarchitecture Synaptic morphology1
Refractory
Description: When the presynaptic M axon was wildtype in a nbea mutant background there was no rescue of connexin36 compared to the mutant synapses within the same animals. Nbeas postsynaptic rescue of Connexin36 at the synapse is not enhanced when the presynaptic neuron is wildtype.

Immunofluorescence staining 6 dpf
Neuroanatomy / Ultrastructure / Cytoarchitecture Synaptic morphology1
Refractory
Description: When the presynaptic M axon was wildtype in a nbea mutant background Glycine receptor expression was rescued not compared to nbea mutant animals.

Immunofluorescence staining 6 dpf
Not Reported: Circadian sleep/wake cycle,  Communications,  Developmental profile,  Emotion,  Immune response,  Learning & memory,  Maternal behavior,  Molecular profile,  Motor phenotype,  Neurophysiology,  Physiological parameters,  Repetitive behavior,  Seizure,  Sensory,  Social behavior,  
 
References: 1:  Miller AC , et al. 2014
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