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Z_NBEA_3_MOSAIC_MCELL
Model Details
Change
No Change
     
Phenotypic Profile
Category Entity Quantity Experimental Paradigm Age at Testing
Neuroanatomy / Ultrastructure / Cytoarchitecture Synaptic morphology1
Decreased
Description: When Mauthner cell is nbea mutant in a wildtype host it loses its sensory input electrical synapses in the hindbrain compared to controls.

 Immunofluorescence staining 6 dpf
Neuroanatomy / Ultrastructure / Cytoarchitecture Dendritic architecture: dendritic tree complexity1
Decreased
Description: When the M cell was nbea mutant in a wildtype animal dendritic complexity was decreased compared to control animals.

 Immunofluorescence staining 6 dpf
Neuroanatomy / Ultrastructure / Cytoarchitecture Synaptic morphology1
Decreased
Description: When the Mauthner cell is nbea mutant in a wildtype animal the GlyR staining on its postsynaptic dendrites in the hindbrain is reduced compared to controls.

 Immunofluorescence staining 6 dpf
Neuroanatomy / Ultrastructure / Cytoarchitecture Dendritic architecture: dendritic length1 No change Immunofluorescence staining 6 dpf
Not Reported: Circadian sleep/wake cycle,  Communications,  Developmental profile,  Emotion,  Immune response,  Learning & memory,  Maternal behavior,  Molecular profile,  Motor phenotype,  Neurophysiology,  Physiological parameters,  Repetitive behavior,  Seizure,  Sensory,  Social behavior,  
 
References: 1:  Miller AC , et al. 2014
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