| Phenotypic Profile |
| Category |
Entity |
Quantity |
Experimental Paradigm |
Age at Testing |
| Molecular profile |
Gene expression1 |
No adverse effect
Description: Injection of mecp2 mRNA had no effect on the expression of il1b in mecp2-null mutants.
|
Quantitative pcr (qrt-pcr) |
1 dpf |
| |
|
Description: Injection of mecp2 mRNA had no effect on the expression of il1b in mecp2-null mutants.
|
|
|
| Molecular profile |
Gene expression1 |
Ameliorated
Description: Injection of mecp2 mRNA ameliorated the decreased tnfa expression in mecp2-null mutants.
|
Quantitative pcr (qrt-pcr) |
1 dpf |
| |
|
Description: Injection of mecp2 mRNA ameliorated the decreased tnfa expression in mecp2-null mutants.
|
|
|
| Molecular profile |
Targeted expression1 |
Restored
Description: Injection of mecp2 mRNA resulted in a 15- to 20- fold overexpression of mecp2 in mecp2-null mutants.
|
Quantitative pcr (qrt-pcr) |
1 dpf |
| |
|
Description: Injection of mecp2 mRNA resulted in a 15- to 20- fold overexpression of mecp2 in mecp2-null mutants.
|
|
|
|
| Not Reported: |
Circadian sleep/wake cycle, Communications, Developmental profile, Emotion, Immune response, Learning & memory, Maternal behavior, Motor phenotype, Neuroanatomy / ultrastructure / cytoarchitecture, Neurophysiology, Physiological parameters, Repetitive behavior, Seizure, Sensory, Social behavior, |
