HELP
Sign In
Quick Links
MindSpec
AutDB Home
Human Gene
Animal Models
PIN
CNV
Reading Room
TOOLS
Advanced Search
User guide
Submit New Gene
Workspace
Pending Updates
Z_MECP2_1_KD_MO_ROBO-SEMA5B
Model Details
Change
No Change
Phenotypic Profile
Category
Entity
Quantity
Experimental Paradigm
Age at Testing
Neuroanatomy / Ultrastructure / Cytoarchitecture
Dendritic architecture: dendritic length
1
Ameliorated
View More
Description:
Co-injection of robo2 and sema5b mRNA ameliorated (90%) the reduction in the total axonal projection length from trigeminal ganglia neurons in mecp2 MO morphants.
Immunofluorescence staining
24 hpf
Description:
Co-injection of robo2 and sema5b mRNA ameliorated (90%) the reduction in the total axonal projection length from trigeminal ganglia neurons in mecp2 MO morphants.
Sensory
Touch
1
Sustained effect
View More
Description:
Co-injection of robo2 and sema5b mRNA rescued the reduction in responseness to tactile stimulation in mecp2 MO morphants.
General observations
48 hpf
Description:
Co-injection of robo2 and sema5b mRNA rescued the reduction in responseness to tactile stimulation in mecp2 MO morphants.
Not Reported:
Circadian sleep/wake cycle
,
Communications
,
Developmental profile
,
Emotion
,
Immune response
,
Learning & memory
,
Maternal behavior
,
Molecular profile
,
Motor phenotype
,
Neurophysiology
,
Physiological parameters
,
Repetitive behavior
,
Seizure
,
Social behavior
,
References:
1:
Leong WY , et al. 2016
HELP
Copyright © 2017 MindSpec, Inc.
