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Z_MECP2_1_KD_MO_HUC-MECP2
Model Details
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Phenotypic Profile
Category
Entity
Quantity
Experimental Paradigm
Age at Testing
Neuroanatomy / Ultrastructure / Cytoarchitecture
Dendritic architecture: dendritic length
1
Ameliorated
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Description:
Expression of HuC-mecp2 ameliorated the reduction in total length and number of projections in trigeminal ganglion neurons in mecp2 MO morphants.
Immunofluorescence staining
24 hpf
Description:
Expression of HuC-mecp2 ameliorated the reduction in total length and number of projections in trigeminal ganglion neurons in mecp2 MO morphants.
Not Reported:
Circadian sleep/wake cycle
,
Communications
,
Developmental profile
,
Emotion
,
Immune response
,
Learning & memory
,
Maternal behavior
,
Molecular profile
,
Motor phenotype
,
Neurophysiology
,
Physiological parameters
,
Repetitive behavior
,
Seizure
,
Sensory
,
Social behavior
,
References:
1:
Leong WY , et al. 2016
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