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construct
M_MECP2_6_KD_SCH-23390
Model Details
Change
No Change
     
Phenotypic Profile
Category Entity Quantity Experimental Paradigm Age at Testing
Repetitive behavior Self grooming: perseveration1
Refractory
Description: Sch-23390 did not affect increased self-grooming in mecp2-sirna injected mice.
Exp Paradigm: NA

Grooming behavior assessments Adult
Social behavior Social memory1
Restored
Description: Sch-23390 increased social novelty preference in mecp2-sirna injected mice.
Exp Paradigm: NA

U-field assay Adult
Learning & memory Object recognition memory1
Refractory
Description: Sch-23390 did not increased novel object preference in mecp2-sirna injected mice.
Exp Paradigm: NA

Object preference test Adult
Not Reported: Circadian sleep/wake cycle,  Communications,  Developmental profile,  Emotion,  Immune response,  Maternal behavior,  Molecular profile,  Motor phenotype,  Neuroanatomy / ultrastructure / cytoarchitecture,  Neurophysiology,  Physiological parameters,  Seizure,  Sensory,  
 
References: 1:  Lee Y , et al. 2019
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