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construct
M_MECP2_34.1_TG_2X_ANTALARMIN
Model Details
Change
No Change
     
Phenotypic Profile
Category Entity Quantity Experimental Paradigm Age at Testing
Emotion Anxiety1
Ameliorated
Description: Treatment with antalarmin reduces anxiety and increases time spent in open arms or lit chamber in elevated plus maze and ligh-dark exploration test respectivel
Exp Paradigm: Light-dark exploration test

Light-dark exploration test 2-3 month
Emotion Anxiety1
Ameliorated
Description: Treatment with antalarmin reduces anxiety and increases time spent in open arms or lit chamber in elevated plus maze and ligh-dark exploration test respectivel
Exp Paradigm: Elevated plus maze test

Elevated plus maze test 2-3 month
Emotion Anxiety1
Ameliorated
Description: Treatment with antalarmin reduces anxiety levels even in mecp2-tg mice previously exposed to social defeat stress prior to testing in elevated plus maze
Exp Paradigm: NA

Post-stress elevated plus maze test 2-3 month
Not Reported: Circadian sleep/wake cycle,  Communications,  Developmental profile,  Immune response,  Learning & memory,  Maternal behavior,  Molecular profile,  Motor phenotype,  Neuroanatomy / ultrastructure / cytoarchitecture,  Neurophysiology,  Physiological parameters,  Repetitive behavior,  Seizure,  Sensory,  Social behavior,  
 
References: 1:  Samaco RC , et al. 2012
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