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M_MECP2_1.3_KO_HT
Model Details
Change
No Change
Phenotypic Profile
Category
Entity
Quantity
Experimental Paradigm
Age at Testing
Motor phenotype
Motor coordination and balance
1
Decreased
View More
Description:
Decreased motor coordination demonstrated by shorter latency to fall
Exp Paradigm:
Female mice: rotorod test
Accelerating rotarod test
6 weeks
Description:
Decreased motor coordination demonstrated by shorter latency to fall
Exp Paradigm:
Female mice: rotorod test
Developmental profile
Size/growth
1
No change
General observations
6.5 weeks
Learning & memory
Cued or contextual fear conditioning
1
No change
Fear conditioning test
6 weeks
Motor phenotype
General locomotor activity
1
No change
Light-dark exploration test
Unreported
Motor phenotype
Grip strength
1
No change
Grip strength test
6.5 weeks
Not Reported:
Circadian sleep/wake cycle
,
Communications
,
Emotion
,
Immune response
,
Maternal behavior
,
Molecular profile
,
Neuroanatomy / ultrastructure / cytoarchitecture
,
Neurophysiology
,
Physiological parameters
,
Repetitive behavior
,
Seizure
,
Sensory
,
Social behavior
,
References:
1:
Schaevitz LR , et al. 2012
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