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Z_CNTNAP2A_3_DM_HT
Model Details
Change
No Change
Phenotypic Profile
Category
Entity
Quantity
Experimental Paradigm
Age at Testing
Sensory
Startle response: acoustic stimulus
1
Abnormal
View More
Description:
cntnap2ab mutants showed an increase in acoustic startle response at 13 dB but not 26 dB compared to controls.
Exp Paradigm:
Short latency C-bend (SLC) sensitivity
Startle response test
5-7 dpf
Description:
cntnap2ab mutants showed an increase in acoustic startle response at 13 dB but not 26 dB compared to controls.
Exp Paradigm:
Short latency C-bend (SLC) sensitivity
Emotion
Habituation to aversive stimuli
1
No change
Startle response test
5-7 dpf
Motor phenotype
Spontaneous and reflexive eye movements
1
No change
Eye movement recording
5-7 dpf
Sensory
Sensorimotor gating
1
No change
Prepulse inhibition
5-7 dpf
Sensory
Startle response: acoustic stimulus
1
No change
Startle response test
5-7 dpf
Sensory
Visual motor response
1
No change
Eye movement recording
5-7 dpf
Not Reported:
Circadian sleep/wake cycle
,
Communications
,
Developmental profile
,
Immune response
,
Learning & memory
,
Maternal behavior
,
Molecular profile
,
Neuroanatomy / ultrastructure / cytoarchitecture
,
Neurophysiology
,
Physiological parameters
,
Repetitive behavior
,
Seizure
,
Social behavior
,
References:
1:
Hoffman EJ , et al. 2016
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