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construct
Z_CNTNAP2A_1_DM_HM_RISPERIDONE/0.001UM
Model Details
Change
No Change
     
Phenotypic Profile
Category Entity Quantity Experimental Paradigm Age at Testing
Circadian sleep/wake cycle Locomotor activity in diurnal cycle1
Side effect
Description: Treatment with 0.001 uM risperidone changed the rest-wake activity cycle, such as average activity at night or while awake, in treated zebrafish mutants.

General observations 5 dpf; 6dpf
Motor phenotype Hyperactivity1
Restored
Description: Treatment with 0.001 uM risperidone restored nighttime hyperactivity in cntnap2ab mutants.

General observations 5 dpf
Not Reported: Communications,  Developmental profile,  Emotion,  Immune response,  Learning & memory,  Maternal behavior,  Molecular profile,  Neuroanatomy / ultrastructure / cytoarchitecture,  Neurophysiology,  Physiological parameters,  Repetitive behavior,  Seizure,  Sensory,  Social behavior,  
 
References: 1:  Hoffman EJ , et al. 2016
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