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Z_CNTNAP2A_1_DM_HM_BETA-ESTRADIOL/1.0UM
Model Details
Change
No Change
Phenotypic Profile
Category
Entity
Quantity
Experimental Paradigm
Age at Testing
Motor phenotype
Hyperactivity
1
Restored
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Description:
Treatment with 1.0 uM beta-estradiol restored nighttime hyperactivity in cntnap2ab mutants, who were indistinguishable from controls.
General observations
5 dpf
Description:
Treatment with 1.0 uM beta-estradiol restored nighttime hyperactivity in cntnap2ab mutants, who were indistinguishable from controls.
Not Reported:
Circadian sleep/wake cycle
,
Communications
,
Developmental profile
,
Emotion
,
Immune response
,
Learning & memory
,
Maternal behavior
,
Molecular profile
,
Neuroanatomy / ultrastructure / cytoarchitecture
,
Neurophysiology
,
Physiological parameters
,
Repetitive behavior
,
Seizure
,
Sensory
,
Social behavior
,
References:
1:
Hoffman EJ , et al. 2016
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