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M_NLGN3_24_KO_HT
Model Details
Change
No Change
Phenotypic Profile
Category
Entity
Quantity
Experimental Paradigm
Age at Testing
Social behavior
Social interaction
1
Decreased
View More
Description:
Female heterozygous mutant mice raised with nlgn3 null littermates spent less time in contact with an unfamiliar female than heterozygous females raised with wildtype littermates.
Exp Paradigm:
NA
Reciprocal social interaction test
2-4 month
Description:
Female heterozygous mutant mice raised with nlgn3 null littermates spent less time in contact with an unfamiliar female than heterozygous females raised with wildtype littermates.
Exp Paradigm:
NA
Emotion
Anxiety
1
No change
Elevated plus maze test
2-4 month
Emotion
Anxiety
1
No change
Open field test
2-4 month
Emotion
Thigmotaxis
1
No change
Open field test
2-4 month
Motor phenotype
General locomotor activity: ambulatory activity
1
No change
Open field test
2-4 month
Not Reported:
Circadian sleep/wake cycle
,
Communications
,
Developmental profile
,
Immune response
,
Learning & memory
,
Maternal behavior
,
Molecular profile
,
Neuroanatomy / ultrastructure / cytoarchitecture
,
Neurophysiology
,
Physiological parameters
,
Repetitive behavior
,
Seizure
,
Sensory
,
References:
1:
Kalbassi S , et al. 2017
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