| Phenotypic Profile |
| Category |
Entity |
Quantity |
Experimental Paradigm |
Age at Testing |
| Neuroanatomy / Ultrastructure / Cytoarchitecture |
Dendritic architecture: spine turnover1 |
Increased
Description: Nlgn3r451c mice show increased turnover of psd95-positive puncta associated spines in the afc compared to wild type mice
Exp Paradigm: Turnover of psd-95 -gfp positive puncta of spines was measured
|
Two-photon microscopy |
3 weeks |
| |
|
Description: Nlgn3r451c mice show increased turnover of psd95-positive puncta associated spines in the afc compared to wild type mice
Exp Paradigm: Turnover of psd-95 -gfp positive puncta of spines was measured |
|
|
| Neuroanatomy / Ultrastructure / Cytoarchitecture |
Dendritic architecture: spine density1 |
No change |
Two-photon microscopy |
3 weeks |
| Neuroanatomy / Ultrastructure / Cytoarchitecture |
Dendritic architecture: spine turnover1 |
No change |
Two-photon microscopy |
3 weeks |
| Neuroanatomy / Ultrastructure / Cytoarchitecture |
Synapse density: excitatory1 |
No change |
Two-photon microscopy |
3 weeks |
|
| Not Reported: |
Circadian sleep/wake cycle, Communications, Developmental profile, Emotion, Immune response, Learning & memory, Maternal behavior, Molecular profile, Motor phenotype, Neurophysiology, Physiological parameters, Repetitive behavior, Seizure, Sensory, Social behavior, |