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construct
M_GRPR_2_KO_HE
Model Details
Change
No Change
     
Phenotypic Profile
Category Entity Quantity Experimental Paradigm Age at Testing
Circadian sleep/wake cycle Circadian rhythm: protein expression periodicity1
Decreased
Description: Decreased release of amylase in response to administration of bombesin
Exp Paradigm: Amylase release assay on acini derived from pancreas after administration of bombesin

Amylase release assay Unreported
Physiological parameters Satiety response1
Decreased
Description: Decreased satiety response in response to increasing doses of bombesin
Exp Paradigm: Glucose intake test after administration of upto 32nmol/kg of bombesin

Glucose intake measurements Unreported
Circadian sleep/wake cycle Circadian rhythm: protein expression periodicity1 No change Amylase release assay Unreported
Developmental profile Developmental trajectory1 No change Histology 10 months
Developmental profile General characteristics1 No change General observations Unreported
Developmental profile Mortality/lethality1 No change General observations Unreported
Developmental profile Size/growth1 No change General observations Unreported
Neuroanatomy / Ultrastructure / Cytoarchitecture Brain development1 No change Histology 10 months
Not Reported: Communications,  Emotion,  Immune response,  Learning & memory,  Maternal behavior,  Molecular profile,  Motor phenotype,  Neurophysiology,  Physiological parameters,  Repetitive behavior,  Seizure,  Sensory,  Social behavior,  
 
References: 1:  Hampton LL , et al. 1998
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