| Phenotypic Profile |
| Category |
Entity |
Quantity |
Experimental Paradigm |
Age at Testing |
| Learning & memory |
Spatial working memory1 |
Decreased
Description: Decreased spatial working memory
Exp Paradigm: Delayed non-match to place task
|
Delayed non-match to place test |
6-8 weeks |
| |
|
Description: Decreased spatial working memory
Exp Paradigm: Delayed non-match to place task |
|
|
| Molecular profile |
Protein expression level evidence1 |
Decreased
Description: Decreased expression of full-length disc1 protein in total brain lysates and purified brain mitochondrial lysates
Exp Paradigm: Disc1 protein expression
|
Western blot |
Unreported |
| |
|
Description: Decreased expression of full-length disc1 protein in total brain lysates and purified brain mitochondrial lysates
Exp Paradigm: Disc1 protein expression |
|
|
| Motor phenotype |
General locomotor activity1 |
No change |
Open field test |
6-8 weeks |
| Neuroanatomy / Ultrastructure / Cytoarchitecture |
Brain morphology1 |
No change |
Histology |
Unreported |
| Sensory |
Sensorimotor gating1 |
No change |
Prepulse inhibition |
6-8 weeks |
|
| Not Reported: |
Circadian sleep/wake cycle, Communications, Developmental profile, Emotion, Immune response, Maternal behavior, Neurophysiology, Physiological parameters, Repetitive behavior, Seizure, Social behavior, |
