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Animal Model >> null >> Z_MECP2_2_KO_HM_MECP2_MO Construct Details |
| Model Details :Z_MECP2_2_KO_HM_MECP2_MO
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Model Type |
Genetic
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Model Genotype |
Homozygous
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Mutation |
Mecp2-null mutants (carrying q63/q63 nonsense mutation generated through N-ethyl-N-nitrosourea (ENU)-mutagenesis) co-injected with mecp2 morpholino. Freshly fertilized zebrafish eggs were injected with mecp2 morpholino (800 microM) at the one- to two-cell stage in a volume of approximately 1 nl. |
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Allele Type |
Knockout |
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Strain of Origin |
AB |
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Genetic Background |
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ES Cell Line |
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Mutant ES Cell Line |
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Model Source |
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Reference |
Leong WY , et al. 2016
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