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Animal Model >> null >> Z_CNTNAP2A_1_DM_HM_RISPERIDONE/0.01UM Construct Details |
Model Details :Z_CNTNAP2A_1_DM_HM_RISPERIDONE/0.01UM
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Model Type |
RESCUE-Pharmaceutical
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Model Genotype |
Homozygous/homozygous
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Mutation |
Double knockout mutants were treated with 0.01 uM risperidone, an antipsychotic drug approved by FDA for irritability and aggressive behavior in ASD, at 5 dpf. |
Allele Type |
Loss-of-function |
Strain of Origin |
Not specified |
Genetic Background |
Not specified |
ES Cell Line |
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Mutant ES Cell Line |
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Model Source |
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Reference |
Hoffman EJ , et al. 2016
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