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Animal Model >> null >> M_NLGN3_6_KI_R451C Construct Details |
| Model Details :M_NLGN3_6_KI_R451C
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Model Type |
Genetic
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Model Genotype |
Hemizygous
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Mutation |
Exon 7 carrying coding mutation (R451C) replaced the wild type exon 7 using a neo cassette as a selectable marker and flanked by loxP sites. |
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Allele Type |
ASD LOF mutation |
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Strain of Origin |
(129X1/SvJ x 129S1/Sv)F1-Kitl+ |
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Genetic Background |
C57BL/6J |
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ES Cell Line |
R1 |
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Mutant ES Cell Line |
Not Specified |
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Model Source |
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Reference |
Rothwell PE , et al. 2014,
Lee CYQ et al. 2023
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