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Animal Model >> null >> M_NLGN3_3_KI_R451C Construct Details |
| Model Details :M_NLGN3_3_KI_R451C
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Model Type |
Genetic
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Model Genotype |
Hemizygous, Homozygous
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Mutation |
A BAC targeting vector with the mutation of CGT (arginine 451) to TGC (cysteine 451) in exon 7 replaced the wild-type sequence. |
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Allele Type |
ASD LOF mutation |
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Strain of Origin |
Not Specified |
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Genetic Background |
C57BL/6 |
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ES Cell Line |
R1 |
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Mutant ES Cell Line |
Not Specified |
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Model Source |
Not Specified |
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Reference |
Chadman KK , et al. 2009,
Etherton M , et al. 2011,
Liu JJ , et al. 2017,
Matta SM et al. 2020
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