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Animal Model >> null >> M_NLGN3_21_KI_R451C_REINSTATE-NLGN3 Construct Details |
| Model Details :M_NLGN3_21_KI_R451C_REINSTATE-NLGN3
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Model Type |
RESCUE-Genetic
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Model Genotype |
Hemizygous
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Mutation |
For NL3 re-expression of 8-week-old male WT and KI mice, adeno-associated virus (AAV) 2/9 serotype (pAAV-CMV-Nlgn3-2A-mCherry-3FLAG or pAAV-CMV-2A-mCherry-3FLAG) was injected (500 nL/hemisphere). . |
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Allele Type |
ASD LOF mutation |
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Strain of Origin |
Not Specified |
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Genetic Background |
C57BL/6J |
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ES Cell Line |
Not Specified |
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Mutant ES Cell Line |
Not Specified |
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Model Source |
The Jackson Laboratory |
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Reference |
Cao W , et al. 2018
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