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Animal Model >> null >> M_MECP2_5_KO_HT_TRAINING Construct Details |
| Model Details :M_MECP2_5_KO_HT_TRAINING
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Model Type |
RESCUE-Behavioral
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Model Genotype |
heterozygous
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Mutation |
Mutant mice were trained on the behavioral testing paradigms before the emergence of deficits (presymptomatic training). to determine whether presymptomatic training bestowed lasting benefits in rotarod performance, early-trained mice were trained beyond 24 weeks of age using the same regimen. |
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Allele Type |
Knockout |
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Strain of Origin |
C57BL/6J |
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Genetic Background |
C57BL/6J |
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ES Cell Line |
E14 TG2a |
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Mutant ES Cell Line |
Not Specified |
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Model Source |
Guy J, et al, Nat. Gen, 2021; 11242117 |
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Reference |
Achilly NP et al. 2021
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