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Animal Model >> null >> M_MECP2_52_CKO_HE_MIDAZOLAM Construct Details |
| Model Details :M_MECP2_52_CKO_HE_MIDAZOLAM
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Model Type |
RESCUE-Pharmaceutical
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Model Genotype |
Hemizygous
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Mutation |
Advillin-Cre; Mecp2^f/y mice were intraperitoneally injected 2mg/kg midazolam (Henry Schein, cat # 054788), a benzodiazepine, which are positive allosteric modulators of GABAARs, to test attenuation of hairy skin over-reactivity in Mecp2 mutant mice.Control mice were injected saline. |
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Allele Type |
Conditional knockout |
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Strain of Origin |
Not specified |
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Genetic Background |
C57BL/6J*129/SvEv*CD1 |
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ES Cell Line |
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Mutant ES Cell Line |
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Model Source |
Jackson Laboratory; RRID:IMSR_JAX:006847; Fan Wang; RRID:IMSR_JAX:032536 |
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Reference |
Orefice LL , et al. 2019
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