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Animal Model >> null >> M_MECP2_5.5_CKO_HE_PVALBN Construct Details |
| Model Details :M_MECP2_5.5_CKO_HE_PVALBN
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Model Type |
Genetic
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Model Genotype |
Hemizygous
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Mutation |
Conditional deletion of exon 3- 4 of Mecp2 in male mice using Pvalb-Cre, in parvalbumin expressing interneurons . Note that phenotypes of these mice are annotated in comparison to the homozygous floxed Mecp2 mice which express a truncated form of the protein |
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Allele Type |
Conditional loss-of-function |
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Strain of Origin |
C57Bl/6 * B6C3H |
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Genetic Background |
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ES Cell Line |
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Mutant ES Cell Line |
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Model Source |
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Reference |
Ito-Ishida A , et al. 2015
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