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Animal Model >> null >> M_MECP2_5.15_CKO_HT Construct Details |
| Model Details :M_MECP2_5.15_CKO_HT
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Model Type |
Genetic
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Model Genotype |
Heterozygous
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Mutation |
Conditional heterozygous deletion of exon 3- 4 of the Mecp2 gene using Advillin-cre, in dorsal root ganglion and trigeminal somatosensory neurons, while Mecp2 expression is preserved in the spinal cord (females) |
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Allele Type |
Conditional loss-of-function |
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Strain of Origin |
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Genetic Background |
129/SvEv * C57BL/6J |
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ES Cell Line |
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Mutant ES Cell Line |
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Model Source |
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Reference |
Orefice LL , et al. 2016
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