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Animal Model >> null >> M_MECP2_5.14_CKO_HE Construct Details |
| Model Details :M_MECP2_5.14_CKO_HE
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Model Type |
Genetic
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Model Genotype |
Hemizygous
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Mutation |
Conditional deletion of exon 3- 4 of the Mecp2 gene in male mice, using Cdx-cre, in all cells caudal to cervical level 2 leading to loss of Mecp2 protein from the DRG and spinal cord |
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Allele Type |
Conditional loss-of-function |
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Strain of Origin |
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Genetic Background |
129/SvEv * C57BL/6J |
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ES Cell Line |
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Mutant ES Cell Line |
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Model Source |
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Reference |
Orefice LL , et al. 2016
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