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 Animal Model >> null >> M_MECP2_34.2_TG_2X_OPRM1KO Construct Details
 Model Details :M_MECP2_34.2_TG_2X_OPRM1KO
 
Model Type RESCUE-Genetic
Model Genotype Transgenic
Mutation Mecp2 transgenic mice, expressing approx 2 fold Mecp2 protein, on a pure FVB/N background were bred to male Oprm1 +/- mice on C57BL/6 background to generate F1 (FVB/N*C57Bl/6) hybrids to check phenotypes resulting from reduction in corticotropin-releasing hormone receptor expression. The strain background as the other F1 hybrids tested (FVB/N*C57Bl/6).
Allele Type
Strain of Origin
Genetic Background (FVB/N*C57Bl/6)
ES Cell Line
Mutant ES Cell Line
Model Source
Reference Samaco RC , et al. 2012
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