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Animal Model >> null >> M_MECP2_11_KO_HE Construct Details |
| Model Details :M_MECP2_11_KO_HE
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Model Type |
Genetic
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Model Genotype |
Hemizygous
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Mutation |
Targeted deletion of the methyl-CpG-binding domain(MBD) coding region on exon 3 and first 170 bp of exon 4 and disruption of mRNA splicing in the Mecp2 gene. |
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Allele Type |
Knockout |
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Strain of Origin |
Not Specified |
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Genetic Background |
129 and 129xC57BL6 |
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ES Cell Line |
R1 129 |
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Mutant ES Cell Line |
Not Specified |
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Model Source |
Not Specified |
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Reference |
Pelka GJ , et al. 2006
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