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Animal Model >> null >> M_MECP2_1.3_KO_HE_DHF Construct Details |
| Model Details :M_MECP2_1.3_KO_HE_DHF
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Model Type |
RESCUE-Pharmaceutical
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Model Genotype |
Homozygous
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Mutation |
Mecp2 knockout mice were administered 80 mg/L of 7,8-Dihydroxyflavone (DHF) in drinking water from 4 weeks of age. 7,8- DHF activates the high affinity BDNF receptor (TrkB) in the CNS. |
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Allele Type |
Knockout |
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Strain of Origin |
Not Specified |
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Genetic Background |
C57BL/6 |
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ES Cell Line |
Not Specified |
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Mutant ES Cell Line |
Not Specified |
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Model Source |
Not Specified |
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Reference |
Johnson RA , et al. 2011
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