HELP     Sign In
Search

No Human Gene Data Available
Chromosome
CNV Locus
CNV Type
# of studies
Animal Model
22
Duplication
 1
 
22
Duplication
 1
 
22
Deletion-Duplication
 22
 
22
Deletion
 2
 
22
Duplication
 1
 

Model Summary

Description of a new model to study the post-transcriptional regulation of synaptic function.

References

Type
Title
Author, Year
Primary
The splicing regulator Rbfox1 (A2BP1) controls neuronal excitation in the mammalian brain.

M_RBFOX2_1_CKO_HM

Model Type: Genetic
Model Genotype: Homozygous
Mutation: Conditional deletion of exons 6-7 of the Rbfox2 gene using Nestin-cre in neuronal, glial and other cell types in the central and peripheral nervouse system
Allele Type: Conditional loss-of-function
Strain of Origin: Not Specified
Genetic Background: Not Specified
ES Cell Line: Not Specified
Mutant ES Cell Line: Not Specified
Model Source: Not Specified

M_RBFOX2_1_CKO_HM

Category
Entity
Quantity
Experimental Paradigm
Age at Testing
Seizures1
 No Change
 General observations
 2-3 months
Seizures1
 No Change
 General observations
 2-3 months
 Not Reported: Circadian sleep/wake cycle, Communications, Developmental profile, Emotion, Homeostasis, Immune response, Learning & memory, Maternal behavior, Molecular profile, Motor phenotype, Neuroanatomy / Ultrastructure / Cytoarchitecture, Neurophysiology, Repetitive behavior, Sensory, Social behavior

 

No Interactions Available
HELP
Copyright © 2017 MindSpec, Inc.