5-Sep |
septin 5 |
|
5413
|
Q99719
|
|
Y2H; IP/WB; in vitro ubiquitination assay
|
Choi P , et al. 2003
|
ABL1 |
c-abl oncogene 1, non-receptor tyrosine kinase |
|
25
|
P00519
|
|
GST; IP/WB; in vitro kinase assay; 2-D gel electrophoresis; MS; WB
|
Ko HS , et al. 2010
|
AIMP2 |
aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 |
|
7965
|
Q13155
|
|
Y2H; IP/WB; in vitro ubiquitination assay
|
Corti O , et al. 2003
|
AURKA |
aurora kinase A |
|
6790
|
O14965
|
|
In vivo ubiquitination assay; IP/WB
|
Lee SB , et al. 2015
|
AURKB |
aurora kinase B |
|
9212
|
Q96GD4
|
|
In vivo ubiquitination assay
|
Lee SB , et al. 2015
|
BACH1 |
BTB and CNC homology 1, basic leucine zipper transcription factor 1 |
|
571
|
O14867
|
|
IP/WB
|
Zenke-Kawasaki Y , et al. 2007
|
BBOX1 |
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 |
|
8424
|
O75936
|
|
IP; LC-MS/MS
|
Huttlin EL , et al. 2015
|
CASP1 |
caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) |
|
834
|
P43527
|
|
WB
|
Kahns S , et al. 2003
|
CASP8 |
caspase 8, apoptosis-related cysteine peptidase |
|
841
|
Q14790
|
|
WB
|
Kahns S , et al. 2003
|
CCNB1 |
cyclin B1 |
|
891
|
P14635
|
|
In vivo ubiquitination assay; in vitro ubiquitination assay
|
Lee SB , et al. 2015
|
CCNE1 |
cyclin E1 |
|
898
|
P24864
|
|
Nickel-agarose pull-down; in vitro ubiquitination assay
|
Staropoli JF , et al. 2003
|
CCT2 |
chaperonin containing TCP1, subunit 2 (beta) |
|
10576
|
P78371
|
|
IP/WB; Size-exclusion chromatography (SEC)
|
Imai Y , et al. 2003
|
CDC20 |
cell division cycle 20 |
|
991
|
Q12834
|
|
in vitro binding assay; IP/WB
|
Lee SB , et al. 2015
|
CDK5 |
cyclin-dependent kinase 5 |
|
1020
|
Q00535
|
|
Metabolic labeling with 32P; WB; IP/WB
|
Avraham E , et al. 2007
|
CRX |
cone-rod homeobox |
|
1406
|
O43186
|
|
Y2H
|
Corominas R , et al. 2014
|
CUL1 |
cullin 1 |
|
8454
|
Q13616
|
|
IP/WB; GST; Nickel-agarose pull-down
|
Staropoli JF , et al. 2003
|
DLX2 |
distal-less homeobox 2 |
|
1746
|
Q07687
|
|
Y2H
|
Corominas R , et al. 2014
|
DNAJA1 |
DnaJ (Hsp40) homolog, subfamily A, member 1 |
|
3301
|
P31689
|
|
IP/WB
|
Imai Y , et al. 2002
|
DNAJB1 |
DnaJ (Hsp40) homolog, subfamily B, member 1 |
|
3337
|
P25685
|
|
IP/WB
|
Imai Y , et al. 2002
|
DRP1 |
Dynamin-1-like protein |
|
10059
|
O00429
|
|
IP/WB; Immunofluorescence ; in vitro ubiquitination assay
|
Wang H , et al. 2011
|
FAM46C |
family with sequence similarity 46, member C |
|
54855
|
Q5VWP2
|
|
Y2H
|
Corominas R , et al. 2014
|
FANCA |
Fanconi anemia, complementation group A |
|
2175
|
O15360
|
|
IP/WB
|
Sumpter R Jr , et al. 2016
|
FANCC |
Fanconi anemia, complementation group C |
|
2176
|
Q00597
|
|
IP/WB; Co-localization
|
Sumpter R Jr , et al. 2016
|
FBXW7 |
F-box and WD repeat domain containing 7 |
|
55294
|
Q969H0
|
|
IP/WB; GST
|
Staropoli JF , et al. 2003
|
FIS1 |
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) |
|
51024
|
Q9Y3D6
|
|
IP/WB; Immunofluorescence ; in vitro ubiquitination assay
|
Cui M , et al. 2010
|
FZR1 |
fizzy/cell division cycle 20 related 1 (Drosophila) |
|
51343
|
Q9UM11
|
|
in vitro binding assay; IP/WB
|
Lee SB , et al. 2015
|
GPR37 |
G protein-coupled receptor 37 (endothelin receptor type B-like) |
|
2861
|
O15354
|
|
IP/WB; WB; in vitro ubiquitination assay
Y2H; IP/WB; in vitro ubiquitination assay
|
Imai Y , et al. 2001
|
GPR37 |
G protein-coupled receptor 37 (endothelin receptor type B-like) |
|
2861
|
O15354
|
|
|
Imai Y , et al. 2002
|
GPR37 |
G protein-coupled receptor 37 (endothelin receptor type B-like) |
|
2861
|
O15354
|
|
|
Dutta P , et al. 2014
|
HEXDC |
hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing |
|
284004
|
Q8WVB3
|
|
Y2H
|
Stelzl U , et al. 2005
|
HSPA1A |
heat shock 70kDa protein 1A |
|
3303
|
P08107
|
|
IP; LC-MS/MS; IP/WB
|
Imai Y , et al. 2002
|
HSPA1A |
heat shock 70kDa protein 1A |
|
3303
|
P08107
|
|
IP/WB; Size-exclusion chromatography (SEC)
|
Imai Y , et al. 2003
|
HSPA4 |
heat shock 70kDa protein 4 |
|
3308
|
P34932
|
|
IP/WB
|
Imai Y , et al. 2002
|
HSPA8 |
heat shock 70kDa protein 8 |
|
3312
|
P11142
|
|
IP/WB
|
Imai Y , et al. 2002
|
LIMK1 |
LIM domain kinase 1 |
|
3984
|
P53667
|
|
IP/WB; in vitro ubiquitination assay
|
Lim MK , et al. 2007
|
LRRK2 |
leucine-rich repeat kinase 2 |
|
120892
|
Q5S007
|
|
IP/WB
|
Smith WW , et al. 2005
|
MAPT |
microtubule-associated protein tau |
|
4137
|
P10636
|
|
IP/WB
|
Petrucelli L , et al. 2004
|
MEOX1 |
mesenchyme homeobox 1 |
|
4222
|
P50221
|
|
Y2H
|
Corominas R , et al. 2014
|
MEOX2 |
Homeobox protein MOX-2 |
|
4223
|
P50222
|
|
Y2H
|
Corominas R , et al. 2014
|
MFN1 |
mitofusin 1 |
|
55669
|
Q8IWA4
|
|
IP/WB; Immunofluorescence ; in vitro ubiquitination assay
|
Tanaka A , et al. 2010
|
MFN2 |
mitofusin 2 |
|
9927
|
O95140
|
|
IP/WB; Immunofluorescence ; in vitro ubiquitination assay
|
Tanaka A , et al. 2010
|
NDUFA4L2 |
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 |
|
56901
|
Q9NRX3
|
|
Y2H
|
Stelzl U , et al. 2005
|
NEK2 |
NIMA-related kinase 2 |
|
4751
|
P51955
|
|
In vivo ubiquitination assay; in vitro ubiquitination assay
|
Lee SB , et al. 2015
|
PACRG |
PARK2 co-regulated |
|
135138
|
Q96M98
|
|
IP/WB; Co-localization; Size-exclusion chromatography (SEC)
|
Imai Y , et al. 2003
|
PAFAH1B2 |
platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
|
5049
|
P68402
|
|
Y2H
|
Stelzl U , et al. 2005
|
PARK2 |
parkinson protein 2, E3 ubiquitin protein ligase (parkin) |
|
5071
|
O60260
|
|
in vitro ubiquitination assay
|
Hampe C , et al. 2006
|
PARK7 |
Parkinson disease (autosomal recessive, early onset) 7 |
|
11315
|
Q99497
|
|
IP/WB
|
Moore DJ , et al. 2004
|
PASK |
PAS domain containing serine/threonine kinase |
|
23178
|
Q96RG2
|
|
IP; LC-MS/MS
|
Huttlin EL , et al. 2015
|
PCYT2 |
phosphate cytidylyltransferase 2, ethanolamine |
|
5833
|
Q99447
|
|
IP; LC-MS/MS
|
Huttlin EL , et al. 2015
|
PDCD2 |
programmed cell death 2 |
|
5134
|
Q16342
|
|
IP/WB; in vitro ubiquitination assay
|
Fukae J , et al. 2009
|
PINK1 |
PTEN induced putative kinase 1 |
|
65018
|
Q9BXM7
|
|
IP/WB; Affinity chromatography
|
Shiba K , et al. 2009
|
PLCG1 |
phospholipase C, gamma 1 |
|
5335
|
P19174
|
|
IP/WB
|
Dehvari N , et al. 2008
|
PLK1 |
polo-like kinase 1 |
|
5347
|
P53350
|
|
In vivo ubiquitination assay; IP/WB; in vitro kinase assay; in vivo kinase assay; Co-localization
|
Lee SB , et al. 2015
|
PSMA1 |
proteasome (prosome, macropain) subunit, alpha type, 1 |
|
5682
|
P25786
|
|
IP/WB
|
Imai Y , et al. 2002
|
PSMA4 |
proteasome (prosome, macropain) subunit, alpha type, 4 |
|
5685
|
P25789
|
|
Y2H; IP/WB
|
Dchsel JC , et al. 2005
|
PSMC5 |
proteasome (prosome, macropain) 26S subunit, ATPase, 5 |
|
5705
|
P62195
|
|
IP/WB
|
Tsai YC , et al. 2003
|
PTTG1 |
pituitary tumor-transforming 1 |
|
9232
|
O95997
|
|
In vivo ubiquitination assay; in vitro ubiquitination assay
|
Lee SB , et al. 2015
|
RAC1 |
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) |
|
5879
|
P63000
|
|
Y2H
|
Stelzl U , et al. 2005
|
RAD1 |
RAD1 homolog (S. pombe) |
|
5810
|
O60671
|
|
Y2H
|
Stelzl U , et al. 2005
|
RANBP2 |
RAN binding protein 2 |
|
5903
|
P49792
|
|
Y2H; IP/WB; GST; in vitro ubiquitination assay
|
Um JW , et al. 2005
|
RBCK1 |
RanBP-type and C3HC4-type zinc finger containing 1 |
|
10616
|
Q9BYM8
|
|
Y2H
|
Corominas R , et al. 2014
|
REL |
v-rel reticuloendotheliosis viral oncogene homolog (avian) |
|
5966
|
Q04864
|
|
Y2H
|
Corominas R , et al. 2014
|
RGS2 |
regulator of G-protein signaling 2, 24kDa |
|
5997
|
P41220
|
|
Y2H
|
Stelzl U , et al. 2005
|
RNF41 |
ring finger protein 41 |
|
10193
|
Q9H4P4
|
|
Y2H; in vitro binding assay; IP/WB
|
Zhong L , et al. 2005
|
SEPT5 |
septin 5 |
|
5413
|
Q99719
|
|
Y2H
|
Corominas R , et al. 2014
|
SIM2 |
single-minded homolog 2 (Drosophila) |
|
6493
|
Q14190
|
|
IP/WB
|
Okui M , et al. 2005
|
SLC6A3 |
solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 |
|
6531
|
Q01959
|
|
Biotinylation assay; IP/WB
IP/WB; WB
|
Jiang H , et al. 2004
|
Slc6a3 |
solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 |
|
13162
|
Q61327
|
|
Biotinylation assay; IP/WB
IP/WB; WB
|
Jiang H , et al. 2004
|
SNCA |
synuclein, alpha (non A4 component of amyloid precursor) |
|
6622
|
P37840
|
|
IP/WB
|
Choi P , et al. 2001
|
SNCAIP |
synuclein, alpha interacting protein |
|
9627
|
Q9Y6H5
|
|
IP/WB; WB; in vitro ubiquitination assay
|
Chung KK , et al. 2001
|
STUB1 |
STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase |
|
10273
|
Q9UNE7
|
|
IP/WB
IP; LC-MS/MS; IP/WB; Co-localization; in vitro binding assay
|
Imai Y , et al. 2002
|
SYT11 |
synaptotagmin XI |
|
23208
|
Q9BT88
|
|
Y2H; IP/WB; WB
|
Huynh DP , et al. 2003
|
TCF4 |
transcription factor 4 |
|
6925
|
B3KVA4
|
|
Y2H
|
Corominas R , et al. 2014
|
TCP1 |
t-complex 1 |
|
6950
|
P17987
|
|
IP/WB; Size-exclusion chromatography (SEC)
|
Imai Y , et al. 2003
|
TNFRSF17 |
Tumor necrosis factor receptor superfamily member 17 |
|
608
|
Q02223
|
|
IP; LC-MS/MS
|
Huttlin EL , et al. 2015
|
TOMM20 |
translocase of outer mitochondrial membrane 20 homolog (yeast) |
|
9804
|
Q15388
|
|
In vivo ubiquitination assay
|
Lee SB , et al. 2015
|
TOMM20 |
translocase of outer mitochondrial membrane 20 homolog (yeast) |
|
9804
|
Q15388
|
|
IP/WB
|
Sumpter R Jr , et al. 2016
|
TRIP13 |
thyroid hormone receptor interactor 13 |
|
9319
|
Q15645
|
|
Y2H
|
Rual JF , et al. 2005
|
TRIP13 |
thyroid hormone receptor interactor 13 |
|
9319
|
Q15645
|
|
Y2H
|
Corominas R , et al. 2014
|
UBC |
ubiquitin C |
|
7316
|
P63279
|
|
IP/WB
|
Sriram SR , et al. 2005
|
UBE2G1 |
ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) |
|
7326
|
P62253
|
|
IP/WB
|
Imai Y , et al. 2001
|
UBE2J1 |
ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast) |
|
51465
|
Q9Y385
|
|
IP/WB
|
Imai Y , et al. 2001
|
UBE2L3 |
ubiquitin-conjugating enzyme E2L 3 |
|
7332
|
P68036
|
|
IP/WB
|
Shimura H , et al. 2000
|
UBE2L3 |
ubiquitin-conjugating enzyme E2L 3 |
|
7332
|
P68036
|
|
IP/WB
|
Lee SB , et al. 2015
|
UBE2L6 |
ubiquitin-conjugating enzyme E2L 6 |
|
9246
|
O14933
|
|
IP/WB
|
Zhang Y , et al. 2000
|
VCP |
valosin containing protein |
|
7415
|
P55072
|
|
IP; LC-MS/MS
|
Huttlin EL , et al. 2015
|
YWHAH |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide |
|
7533
|
Q04917
|
|
IP/WB
|
Sato S , et al. 2005
|
Dlg1 |
discs, large homolog 1 (Drosophila) |
|
13383
|
Q811D0
|
|
FRAP
|
Stiffler MA , et al. 2006
|
Ptpn5 |
protein tyrosine phosphatase, non-receptor type 5 |
|
19259
|
P54830
|
|
IP/WB; in vitro ubiquitination assay
|
Kurup PK , et al. 2015
|
Rgs3 |
regulator of G-protein signaling 3 |
|
50780
|
Q9DC04
|
|
Protein microarray; FRAP
|
Stiffler MA , et al. 2006
|
CAMK2A |
calcium/calmodulin-dependent protein kinase II alpha |
|
25400
|
P11275
|
|
IP/WB
|
Fallon L , et al. 2001
|
CASK |
calcium/calmodulin-dependent serine protein kinase (MAGUK family) |
|
29647
|
Q62915
|
|
GST; IP/WB
|
Fallon L , et al. 2001
|
Dlg4 |
discs, large homolog 4 (Drosophila) |
|
29495
|
P31016
|
|
IP/WB
|
Fallon L , et al. 2001
|
Egfr |
epidermal growth factor receptor |
|
13649
|
Q01279
|
|
IP/WB
|
Fallon L , et al. 2006
|
EPS15 |
epidermal growth factor receptor pathway substrate 15 |
|
13858
|
P42567
|
|
GST; in vitro ubiquitination assay; Nickel-agarose pull-down
|
Fallon L , et al. 2006
|
GRIN2B |
glutamate receptor, ionotropic, N-methyl D-aspartate 2B |
|
24410
|
Q00960
|
|
IP/WB
|
Fallon L , et al. 2001
|
HOMER1 |
homer homolog 1 (Drosophila) |
|
29456
|
Q9Z214
|
|
IP/WB
|
Fallon L , et al. 2001
|
LOC656767 |
serine/threonine-protein kinase PINK1, mitochondrial |
|
656767
|
D6WMX4
|
|
in vitro kinase assay; in vitro binding assay
|
Norkett R , et al. 2015
|
SNCA |
synuclein, alpha (non A4 component of amyloid precursor) |
|
6622
|
P37840
|
|
IP/WB
|
Norris KL , et al. 2015
|
TUBA1A |
tubulin, alpha 1A |
|
7846
|
Q71U36
|
|
IP/WB; WB
|
Ren Y , et al. 2003
|
TUBB |
tubulin, beta |
|
203068
|
P07437
|
|
IP/WB; WB
|
Ren Y , et al. 2003
|
TUBG1 |
tubulin, gamma 1 |
|
7283
|
P23258
|
|
IP/WB
|
Zhao J , et al. 2003
|
UBC |
ubiquitin C |
|
7316
|
P63279
|
|
UV-cross-linking assay; in vitro binding assay; Size-exclusion chromatography (SEC); Fluoppi assay
|
Norkett R , et al. 2015
|
Ube2l3 |
ubiquitin-conjugating enzyme E2L 3 |
|
363836
|
B2RZA9
|
|
ITC; NMR spectroscopy
|
Sauv V , et al. 2015
|
eIF-4E |
Eukaryotic initiation factor 4E |
|
45525
|
P48598
|
|
IP/WB
|
Ottone C , et al. 2010
|