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Relevance to Autism

Genetic association has been found between the LZTS2 gene and autism in two large cohorts (AGRE and ACC) of European ancestry and replicated in two other cohorts (CAP and CART) (Wang et al., 2009).

Molecular Function

tumor suppressor

External Links

        

References

Type
Title
Type of Disorder
Associated Disorders
Author, Year
Primary
Common genetic variants on 5p14.1 associate with autism spectrum disorders.
ASD
Positive Association
A genome-wide association study of autism incorporating autism diagnostic interview-revised, autism diagnostic observation schedule, and social res...
ASD
Highly Cited
LZTS2 is a novel beta-catenin-interacting protein and regulates the nuclear export of beta-catenin.
Recent Recommendation
LAPSER1/LZTS2: a pluripotent tumor suppressor linked to the inhibition of katanin-mediated microtubule severing.

Rare

No Rare Variants Available

Common

Variant ID
Polymorphism
SNP ID
Allele Change
Residue Change
Population Origin
Population Stage
Author, Year
 GEN147C001 
 5KB_downstream_variant 
 rs807023 
 c.2564A>C 
 A>C 
 US and European 
 Discovery 
 GEN147C002 
 downstream_gene_variant 
 rs807023 
 c.2564A>C 
  
 Discovery cohort: 2165 participants from AGRE 
 Discovery 
Chromosome
CNV Locus
CNV Type
# of studies
Animal Model
10
Duplication
 1
 
10
Duplication
 1
 
10
Deletion
 1
 
10
Duplication
 1
 
10
Duplication
 2
 
10
Deletion
 1
 

No Animal Model Data Available


Interactor Symbol Interactor Name Interactor Organism Entrez ID Uniprot ID Interaction Type Evidence Reference
ABT1 activator of basal transcription 1 29777 Q9ULW3 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
ACAD11 Acyl-CoA dehydrogenase family member 11 84129 Q709F0 IP; LC-MS/MS
Huttlin EL , et al. 2015
AEN apoptosis enhancing nuclease 64782 Q8WTP8 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 116987 Q9UPQ3 IP; LC-MS/MS
Huttlin EL , et al. 2015
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 NM_001042535 Q86ST5 IP; LC-MS/MS
Huttlin EL , et al. 2015
AMPD2 adenosine monophosphate deaminase 2 271 B2RB47 IP; LC-MS/MS
Huttlin EL , et al. 2015
ANKRD11 ankyrin repeat domain 11 29123 Q6UB99 Y2H
Corominas R , et al. 2014
ANKRD36BP1 ankyrin repeat domain 36B pseudogene 1 84832 Q96IX9 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
AP1M1 adaptor-related protein complex 1, mu 1 subunit 8907 Q59EK3 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
APC adenomatous polyposis coli 324 P25054 IP; LC-MS/MS
Huttlin EL , et al. 2015
ARHGAP32 Rho GTPase activating protein 32 9743 A7KAX9 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
ARMC7 armadillo repeat containing 7 79637 Q9H6L4 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 9915 Q9HBZ2 Y2H
Corominas R , et al. 2014
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 259266 B3KWI2 IP; LC-MS/MS
Huttlin EL , et al. 2015
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2 NM_145691 Q8N5M1 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
AZI1 Centrosomal protein of 131 kDa 22994 Q9UPN4-2 IP; LC-MS/MS
Huttlin EL , et al. 2015
BAHD1 bromo adjacent homology domain containing 1 22893 Q8TBE0 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
BEX2 brain expressed X-linked 2 84707 Q9BXY8 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
BMS1P5 BMS1 pseudogene 5 NR_003611 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
BYSL bystin-like 705 Q13895 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
C14ORF105 chromosome 14 open reading frame 105 55195 B7ZL43 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
C19ORF66 chromosome 19 open reading frame 66 55337 Q9NUL5 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
C1ORF109 chromosome 1 open reading frame 109 54955 Q9NX04 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
C20ORF195 chromosome 20 open reading frame 195 79025 Q9BVV2 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
C6ORF165 chromosome 6 open reading frame 165 154313 Q8IYR0 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
C8ORF33 chromosome 8 open reading frame 33 65265 Q9H7E9 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
CARD9 caspase recruitment domain family, member 9 64170 A0A024R8F1 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
CBX8 chromobox homolog 8 57332 Q9HC52 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
CCDC12 coiled-coil domain containing 12 151903 J3KR35 IP; LC-MS/MS
Huttlin EL , et al. 2015
CCNC cyclin C 892 P24863 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
CCNG1 cyclin G1 900 P51959 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
CCNK cyclin K 8812 O75909 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
CD3EAP CD3e molecule, epsilon associated protein 10849 O15446 IP; LC-MS/MS
Huttlin EL , et al. 2015
CDC23 cell division cycle 23 8697 Q9UJX2 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
CDK18 cyclin-dependent kinase 18 5129 A0A024R996 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
CDKL3 cyclin-dependent kinase-like 3 51265 Q8IVW4 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
CEP290 centrosomal protein 290kDa 80184 O15078 IP; LC-MS/MS
Huttlin EL , et al. 2015
CEP57L1 centrosomal protein 57kDa-like 1 285753 Q8IYX8 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 54927 A4D1N4 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
CLIP4 CAP-Gly domain-containing linker protein 4 79745 Q8N3C7 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
CNNM3 cyclin M3 26505 Q8NE01 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 10898 O95639 IP; LC-MS/MS
Huttlin EL , et al. 2015
CRNKL1 crooked neck pre-mRNA splicing factor-like 1 (Drosophila) 51340 Q9BZJ0 IP; LC-MS/MS
Huttlin EL , et al. 2015
CTC1 CTS telomere maintenance complex component 1 80169 Q2NKJ3 IP; LC-MS/MS
Huttlin EL , et al. 2015
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) 54165 Q96GG9 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
DGCR6 DiGeorge syndrome critical region gene 6 8214 Q14129 Y2H
Corominas R , et al. 2014
DGCR6L DiGeorge syndrome critical region gene 6-like 85359 Q9BY27 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
DIPA coiled-coil domain containing 85B 11007 Q15834 Y2H
Rual JF , et al. 2005
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 1859 Q13627 IP; LC-MS/MS
Huttlin EL , et al. 2015
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 1859 Q13627 IP; LC-MS/MS
Li J , et al. 2016
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B 9149 Q9Y463 IP; LC-MS/MS
Huttlin EL , et al. 2015
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 8445 Q92630 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
EAPP E2F-associated phosphoprotein 55837 Q56P03 IP; LC-MS/MS
Huttlin EL , et al. 2015
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 1962 Q08426 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
EIF3D eukaryotic translation initiation factor 3, subunit D 8664 O15371 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
EIF4E2 eukaryotic translation initiation factor 4E family member 2 9470 O60573 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
ERCC3 excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) 2071 P19447 IP; LC-MS/MS
Huttlin EL , et al. 2015
FAM103A1 family with sequence similarity 103, member A1 83640 Q9BTL3 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
FAM107A family with sequence similarity 107, member A 11170 O95990 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
FAM124B Protein FAM124B 79843 Q9H5Z6 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
FAM161A family with sequence similarity 161, member A 84140 Q3B820 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
FAM74A4 family with sequence similarity 74, member A4 401508 Q5TZK3 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
FANCL Fanconi anemia, complementation group L 55120 Q9NW38 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
FBF1 Fas (TNFRSF6) binding factor 1 85302 Q8TES7 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
FEM1C fem-1 homolog c (C. elegans) 56929 Q96JP0 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
FGF12 fibroblast growth factor 12 2257 P61328 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
FKBP6 FK506 binding protein 6, 36kDa 8468 O75344 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
FMR1 fragile X mental retardation 1 2332 G8JLE9 PAR-CLIP
Ascano M Jr , et al. 2012
FRG1 FSHD region gene 1 2483 Q14331 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
FRMD6 FERM domain containing 6 122786 Q96NE9 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
GCC1 GRIP and coiled-coil domain containing 1 79571 Q96CN9 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
GEM GTP binding protein overexpressed in skeletal muscle 2669 A0A024R9F5 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
GMCL1P1 germ cell-less, spermatogenesis associated 1 pseudogene 1 64396 Q8NEA9 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like 54552 Q05DU1 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
GPATCH2L G patch domain containing 2-like 55668 Q9NWQ4 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
GRB2 growth factor receptor-bound protein 2 2885 P62993 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa 2965 P32780 IP; LC-MS/MS
Huttlin EL , et al. 2015
HIC2 hypermethylated in cancer 2 23119 Q96JB3 IP; LC-MS/MS
Huttlin EL , et al. 2015
HIPK2 homeodomain interacting protein kinase 2 28996 Q9H2X6 IP; LC-MS/MS
Huttlin EL , et al. 2015
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 I4EC15 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
HM13 histocompatibility (minor) 13 81502 Q8TCT9 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
HOMER2 homer homolog 2 (Drosophila) 9455 Q9NSB8 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
HSPD1 heat shock 60kDa protein 1 (chaperonin) 3329 P10809 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
IQCE IQ motif containing E 23288 Q6IPM2 Y2H
Corominas R , et al. 2014
ISCA1 iron-sulfur cluster assembly 1 homolog (S. cerevisiae) 81689 Q9BUE6 IP; LC-MS/MS
Huttlin EL , et al. 2015
KAT5 K(lysine) acetyltransferase 5 10524 Q92993 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
KAZN kazrin, periplakin interacting protein 23254 Q674X7 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
KIAA0528 C2 calcium-dependent domain containing 5 9847 Q86YS7 IP; LC-MS/MS
Huttlin EL , et al. 2015
KIAA0889 Protein SOGA1 140710 O94964-2 IP; LC-MS/MS
Huttlin EL , et al. 2015
KIAA1683 KIAA1683 80726 Q9H0B3 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
KIAA1683 KIAA1683 80726 Q9H0B3 IP; LC-MS/MS
Huttlin EL , et al. 2015
KIF7 kinesin family member 7 374654 Q2M1P5 IP; LC-MS/MS
Huttlin EL , et al. 2015
KIF9 kinesin family member 9 64147 A8K932 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
KIFC3 kinesin family member C3 3801 Q9BVG8 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 3838 P52292 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
LASP1 LIM and SH3 protein 1 NM_006148 B4DIC4 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
LCK lymphocyte-specific protein tyrosine kinase 3932 P06239 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
LIN37 lin-37 DREAM MuvB core complex component 55957 Q96GY3 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
LMO1 LIM domain only 1 (rhombotin 1) 4004 P25800 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
LMO2 Rhombotin-2 4005 P25791 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
LZTS1 Leucine zipper putative tumor suppressor 1 11178 Q9Y250-2 IP; LC-MS/MS
Huttlin EL , et al. 2015
MAB21L3 mab-21-like 3 (C. elegans) 126868 Q8N8X9 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
MAGEB4 melanoma antigen family B4 4115 O15481 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
MEMO1 mediator of cell motility 1 51072 Q9Y316 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
MIS18BP1 MIS18 binding protein 1 55320 Q6P0N0 IP; LC-MS/MS
Huttlin EL , et al. 2015
MORF4L1 mortality factor 4 like 1 10933 B7Z6R1 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
MORF4L2 mortality factor 4 like 2 9643 Q15014 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
MORN3 MORN repeat containing 3 283385 Q6PF18 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
MOS v-mos Moloney murine sarcoma viral oncogene homolog 4342 P00540 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
MTA1 metastasis associated 1 9112 Q13330 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
MYO9A myosin IXA 4649 B2RTY4 IP; LC-MS/MS
Huttlin EL , et al. 2015
NBN nibrin 4683 O60934 IP; LC-MS/MS
Huttlin EL , et al. 2015
NCAPD3 non-SMC condensin II complex, subunit D3 23310 P42695 IP; LC-MS/MS
Huttlin EL , et al. 2015
NCAPH2 non-SMC condensin II complex, subunit H2 29781 Q6IBW4 IP; LC-MS/MS
Huttlin EL , et al. 2015
NCBP2 nuclear cap binding protein subunit 2, 20kDa 22916 E9PAR5 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
NCK2 NCK adaptor protein 2 8440 O43639 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
NDE1 nudE nuclear distribution E homolog 1 (A. nidulans) 54820 Q9NXR1 Y2H
Corominas R , et al. 2014
NEBL nebulette 10529 O76041 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
NEK6 NIMA-related kinase 6 10783 Q9HC98 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
NINL ninein-like 22981 Q9Y2I6 Y2H
Rual JF , et al. 2005
NIP7 NIP7, nucleolar pre-rRNA processing protein 51388 Q9Y221 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 55270 Q9NV35 IP; LC-MS/MS
Huttlin EL , et al. 2015
OTUB2 OTU domain, ubiquitin aldehyde binding 2 78990 Q96DC9 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7 57144 B0AZM9 Y2H
Rual JF , et al. 2005
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 5305 P48426 IP; LC-MS/MS
Huttlin EL , et al. 2015
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta 8396 P78356 IP; LC-MS/MS
Huttlin EL , et al. 2015
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma 79837 B3KQV3 IP; LC-MS/MS
Huttlin EL , et al. 2015
PITX1 paired-like homeodomain 1 5307 P78337 Y2H
Corominas R , et al. 2014
PLCG1 phospholipase C, gamma 1 5335 P19174 IP; LC-MS/MS
Huttlin EL , et al. 2015
PLEKHN1 pleckstrin homology domain containing, family N member 1 84069 Q494U1 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
POLDIP3 polymerase (DNA-directed), delta interacting protein 3 84271 Q9BY77 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
POLR1C polymerase (RNA) I polypeptide C, 30kDa 9533 O15160 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
POLR1E polymerase (RNA) I polypeptide E, 53kDa 64425 Q9GZS1 IP; LC-MS/MS
Huttlin EL , et al. 2015
PPP1R18 protein phosphatase 1, regulatory subunit 18 170954 Q6NYC8 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
PQBP1 polyglutamine binding protein 1 10084 O60828 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit 5565 O43741 Y2H
Corominas R , et al. 2014
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit 5565 O43741 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 5682 P25786 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
QARS glutaminyl-tRNA synthetase 5859 P47897 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
RAB11FIP5 RAB11 family interacting protein 5 (class I) 26056 Q9BXF6 IP; LC-MS/MS
Huttlin EL , et al. 2015
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 5879 P63000 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
RAD51D RAD51 homolog D (S. cerevisiae) 5892 O75771 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 54715 Q9NWB1 Y2H
Lim J , et al. 2006
RBM15 RNA binding motif protein 15 64783 Q96T37 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
RBM41 RNA binding motif protein 41 55285 Q96IZ5 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
RBPMS RNA binding protein with multiple splicing 11030 Q93062 Y2H
Rual JF , et al. 2005
RCOR3 REST corepressor 3 NM_001136225 Q9P2K3 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
RECQL4 ATP-dependent DNA helicase Q4 9401 O94761 IP; LC-MS/MS
Huttlin EL , et al. 2015
RHNO1 RAD9-HUS1-RAD1 interacting nuclear orphan 1 83695 Q9BSD3 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
RHPN1 rhophilin, Rho GTPase binding protein 1 114822 Q8TCX5 IP; LC-MS/MS
Huttlin EL , et al. 2015
RIN1 Ras and Rab interactor 1 9610 Q13671 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
RNF41 ring finger protein 41 10193 Q9H4P4 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
RTP5 receptor (chemosensory) transporter protein 5 (putative) 285093 Q14D33 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 862 B2R6I9 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
SBF1 SET binding factor 1 6305 O95248 IP; LC-MS/MS
Huttlin EL , et al. 2015
SCNM1 sodium channel modifier 1 79005 Q9BWG6 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
SESTD1 SEC14 and spectrin domains 1 91404 B3KTX3 IP; LC-MS/MS
Huttlin EL , et al. 2015
SH2D4A SH2 domain containing 4A 63898 Q9H788 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
SH3RF2 SH3 domain containing ring finger 2 153769 Q08AM8 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
SIPA1L1 signal-induced proliferation-associated 1 like 1 26037 O43166 IP; LC-MS/MS
Huttlin EL , et al. 2015
SIPA1L2 signal-induced proliferation-associated 1 like 2 57568 Q9P2F8 IP; LC-MS/MS
Huttlin EL , et al. 2015
SIPA1L3 signal-induced proliferation-associated 1 like 3 23094 O60292 IP; LC-MS/MS
Huttlin EL , et al. 2015
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3 51296 Q8IY34 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 293 P12236 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
SLU7 SLU7 splicing factor homolog (S. cerevisiae) 10569 O95391 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
SMC2 structural maintenance of chromosomes 2 10592 O95347 IP; LC-MS/MS
Huttlin EL , et al. 2015
SMIM3 small integral membrane protein 3 85027 Q9BZL3 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
SNHG11 small nucleolar RNA host gene 11 (non-protein coding) NR_003239 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
SNW1 SNW domain containing 1 22938 Q13573 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
SNX31 sorting nexin 31 169166 Q8N9S9 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
SPATA2 spermatogenesis associated 2 9825 A8K0S9 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
SPATA24 spermatogenesis associated 24 202051 Q86W54 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
SPATC1L spermatogenesis and centriole associated 1-like 84221 Q9H0A9 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 6687 Q9UQ90 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
SRSF2 serine/arginine-rich splicing factor 2 6427 Q01130 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein 117178 Q9Y2D8 IP; LC-MS/MS
Huttlin EL , et al. 2015
STAC SH3 and cysteine rich domain 6769 B4DR96 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 6832 Q8IYB8 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 6839 O43463 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
TBC1D7 TBC1 domain family, member 7 51256 Q9P0N9 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
TCEA2 transcription elongation factor A (SII), 2 6919 Q15560 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) 6924 Q14241 IP; LC-MS/MS
Huttlin EL , et al. 2015
TCHP Trichoplein keratin filament-binding protein 84260 Q9BT92 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
TEAD4 TEA domain family member 4 7004 Q15561 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
THAP10 THAP domain containing 10 56906 Q9P2Z0 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
THAP7 THAP domain containing 7 80764 Q9BT49 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
TNIP3 TNFAIP3 interacting protein 3 79931 Q96KP6 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
TRAF2 TNF receptor-associated factor 2 7186 Q12933 Y2H
Rual JF , et al. 2005
TRIM29 tripartite motif containing 29 23650 Q14134 Y2H
Rual JF , et al. 2005
TRIM29 tripartite motif containing 29 23650 Q14134 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
TRIM42 tripartite motif containing 42 287015 Q8IWZ5 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
TROAP trophinin associated protein 10024 Q12815 IP; LC-MS/MS
Huttlin EL , et al. 2015
TSC1 tuberous sclerosis 1 7248 Q92574 Y2H
Sakai Y , et al. 2011
TSNAX translin-associated factor X 7257 Q99598 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
TSSC4 tumor suppressing subtransferable candidate 4 10078 Q9Y5U2 IP; LC-MS/MS
Huttlin EL , et al. 2015
TTC23 tetratricopeptide repeat domain 23 64927 Q5W5X9 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
TTC31 tetratricopeptide repeat domain 31 NM_022492 Q49AM3 IP; LC-MS/MS
Huttlin EL , et al. 2015
TTLL4 tubulin tyrosine ligase-like family, member 4 9654 Q14679 IP; LC-MS/MS
Huttlin EL , et al. 2015
TXNL4A thioredoxin-like 4A 10907 P83876 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
UNC119 Protein unc-119 homolog A 9094 Q13432 IP; LC-MS/MS
Huttlin EL , et al. 2015
USF2 Upstream stimulatory factor 2 7392 Q15853 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
USP2 ubiquitin specific peptidase 2 9099 E9PPM2 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
UTP14C UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast) 9724 Q5TAP6 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
WDR33 WD repeat domain 33 55339 Q9C0J8 IP; LC-MS/MS
Huttlin EL , et al. 2015
WDYHV1 WDYHV motif containing 1 55093 Q96HA8 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
WT1-AS WT1 antisense RNA 51352 Q06250 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
ZBTB25 Zinc finger and BTB domain-containing protein 25 7597 P24278 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
ZBTB38 zinc finger and BTB domain containing 38 253461 Q8NAP3 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
ZGPAT zinc finger, CCCH-type with G patch domain 84619 Q8N5A5 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
ZKSCAN3 zinc finger with KRAB and SCAN domains 3 80317 Q9BRR0 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
ZMAT1 zinc finger, matrin-type 1 84460 A7MD47 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
ZMAT2 zinc finger, matrin-type 2 153527 Q96NC0 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
ZMYM1 zinc finger, MYM-type 1 79830 Q5SVZ6 IP; LC-MS/MS
Huttlin EL , et al. 2015
ZMYM6 zinc finger, MYM-type 6 9204 O95789 IP; LC-MS/MS
Huttlin EL , et al. 2015
ZMYND19 zinc finger, MYND-type containing 19 116225 Q96E35 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
ZNF20 zinc finger protein 20 7568 P17024 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
ZNF250 zinc finger protein 250 58500 B3KNS9 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
ZNF324 zinc finger protein 324 25799 O75467 IP; LC-MS/MS
Huttlin EL , et al. 2015
ZNF408 zinc finger protein 408 79797 B4DXY4 IP; LC-MS/MS
Huttlin EL , et al. 2015
ZNF417 zinc finger protein 417 147687 Q8TAU3 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
ZNF426 zinc finger protein 426 79088 Q9BUY5 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
ZNF446 zinc finger protein 446 NM_017908 Q9NWS9 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
ZNF490 zinc finger protein 490 57474 Q9ULM2 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
ZNF572 zinc finger protein 572 137209 Q7Z3I7 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
ZNF581 zinc finger protein 581 51545 Q9P0T4 Y2H
Rual JF , et al. 2005
ZNF581 zinc finger protein 581 51545 Q9P0T4 Y2H; bimolecular fluorescence complementation assay
Rolland T , et al. 2014
ZNF644 zinc finger protein 644 84146 Q9H582 IP; LC-MS/MS
Huttlin EL , et al. 2015
ZNF785 Zinc finger protein 785 146540 A8K8V0-2 IP; LC-MS/MS
Huttlin EL , et al. 2015
Shank3 SH3 and multiple ankyrin repeat domains 3 59312 Q9JLU4 IP; Co-localization; Bimolecular fluorescence complementation assay; IP/WB; Y2H
Schmeisser MJ , et al. 2009
Spar1 SH3 and multiple ankyrin repeat domains 3 100488068 IP; Co-localization; Bimolecular fluorescence complementation assay; IP/WB; Y2H
Gessert S , et al. 2011
shank1 N/A 100486091 N/A IP/WB
Gessert S , et al. 2011
shank2 SH3 and multiple ankyrin repeat domains 2 734458 Q52KW0 IP/WB
Gessert S , et al. 2011
shank3 N/A NA IP/WB
Gessert S , et al. 2011

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