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No Human Gene Data Available
Chromosome
CNV Locus
CNV Type
# of studies
Animal Model
19
Duplication
 1
 
19
Duplication
 1
 
19
Duplication
 1
 
19
Duplication
 1
 

Model Summary

Homer deletion mimics the behavioral and neurochemical phenotype produced by repeated cocaine administration.

References

Type
Title
Author, Year
Primary
Homer proteins regulate sensitivity to cocaine.

M_HOMER3_1_KO_HM

Model Type: Genetic
Model Genotype: Homozygous
Mutation: Homologous recombination mediated deletion of exon 3 of Homer3 gene.
Allele Type: Targeted (Knock Out)
Strain of Origin: Not specified
Genetic Background: Not specified
ES Cell Line: Not specified
Mutant ES Cell Line: Not specified
Model Source: Not specified

M_HOMER3_1_KO_HM

Category
Entity
Quantity
Experimental Paradigm
Age at Testing
Reward reinforced choice behavior1
 No change
 Conditioned place preference test
 Unreported
General locomotor activity1
 No change
 Conditioned place preference test
 Unreported
 Not Reported: Circadian sleep/wake cycle, Communications, Developmental profile, Emotion, Immune response, Maternal behavior, Molecular profile, Neuroanatomy / ultrastructure / cytoarchitecture, Neurophysiology, Physiological parameters, Repetitive behavior, Seizure, Sensory, Social behavior

 

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