FABP3
Homo sapiens
Gene Name: Fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
Aliases: FABP11, H-FABP, M-FABP, MDGI, O-FABP
Chromosome No: 1
Chromosome Band: 1p35.2
Genetic Category: Functional/rare single gene variant-Functional
Aliases: FABP11, H-FABP, M-FABP, MDGI, O-FABP
Chromosome No: 1
Chromosome Band: 1p35.2
Genetic Category: Functional/rare single gene variant-Functional
Summary Statistics:
ASD Reports: 2
Recent Reports: 0
Annotated variants: 1
Associated CNVs: 4
Evidence score: 0
ASD Reports: 2
Recent Reports: 0
Annotated variants: 1
Associated CNVs: 4
Evidence score: 0
| Associated Disorders: |
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Relevance to Autism
Fabp3-deficient mice exhibited decreased performance in social motivation and novelty seeking compared to wild-type mice (Shimamoto et al., 2014).
Molecular Function
FABPs are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.
External Links
References
Type
Title
Type of Disorder
Associated Disorders
Author, Year
Primary
Functional characterization of FABP3, 5 and 7 gene variants identified in schizophrenia and autism spectrum disorder and mouse behavioral studies.
ASD
SCZ
Support
FABP3 in the Anterior Cingulate Cortex Modulates the Methylation Status of the Glutamic Acid Decarboxylase67 Promoter Region.