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Relevance to Autism

De novo variants in this gene were identified in two separate reports using ASD probands from the Simons Simplex Collection (Sanders et al. 2012a, 2012b)

Molecular Function

The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon.

External Links

        

References

Type
Title
Type of Disorder
Associated Disorders
Author, Year
Primary
Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations.
ASD
Support
Comprehensive molecular testing in patients with high functioning autism spectrum disorder.
ASD
Support
A clinical utility study of exome sequencing versus conventional genetic testing in pediatric neurology.
Psychomotor retardation, microcephaly
Support
Large-scale discovery of novel genetic causes of developmental disorders.
DD
Support
Clinical features associated with CTNNB1 de novo loss of function mutations in ten individuals.
DD, ID
Hypotonia, spasticity, microcephaly
Support
A new intellectual disability syndrome caused by CTNNB1 haploinsufficiency.
ID
Support
Clinical exome sequencing: results from 2819 samples reflecting 1000 families.
Autosomal dominant mental retardation-19
DD, ID, microcephaly
Support
Lessons Learned from Large-Scale, First-Tier Clinical Exome Sequencing in a Highly Consanguineous Population.
DD, ID
Autistic features
Support
Dominant -catenin mutations cause intellectual disability with recognizable syndromic features.
ID
Autistic features
Support
Meta-analysis of 2,104 trios provides support for 10 new genes for intellectual disability.
ID
Support
Exonic Mosaic Mutations Contribute Risk for Autism Spectrum Disorder.
ASD
Support
Multiplex targeted sequencing identifies recurrently mutated genes in autism spectrum disorders.
ASD
Support
Altered proliferation and networks in neural cells derived from idiopathic autistic individuals.
ASD
Support
Improved diagnostic yield compared with targeted gene sequencing panels suggests a role for whole-genome sequencing as a first-tier genetic test.
DD, microcephaly
Support
Diagnostic exome sequencing in persons with severe intellectual disability.
ID
Epilepsy, ASD
Support
A de novo CTNNB1 nonsense mutation associated with syndromic atypical hyperekplexia, microcephaly and intellectual disability: a case report.
ID
Support
Exome sequencing identifies a de novo mutation of CTNNB1 gene in a patient mainly presented with retinal detachment, lens and vitreous opacities, m...
DD, microcephaly
Recent Recommendation
Deletion of CTNNB1 in inhibitory circuitry contributes to autism-associated behavioral defects.
Recent Recommendation
De novo mutations in congenital heart disease with neurodevelopmental and other congenital anomalies.
Congenital heart disease (CHD)
ASD, DD, ID
Recent Recommendation
Low load for disruptive mutations in autism genes and their biased transmission.
ASD
Recent Recommendation
Hepatocyte Growth Factor Modulates MET Receptor Tyrosine Kinase and -Catenin Functional Interactions to Enhance Synapse Formation.

Rare

Variant ID
Variant Type
Allele Change
Residue Change
Inheritance Pattern
Inheritance Association
Family Type
Author, Year
 GEN472R001 
 missense_variant 
 c.1652C>T 
 p.Thr551Met 
 De novo 
 NA 
 Simplex 
 GEN472R002 
 stop_gained 
 c.1512G>A 
 p.Trp504Ter 
 De novo 
 NA 
 Simplex 
 GEN472R003 
 copy_number_loss 
  
  
 De novo 
 NA 
 Simplex 
 GEN472R004 
 frameshift_variant 
 c.1272_1275del 
 p.Ser425ThrfsTer11 
 De novo 
 NA 
  
 GEN472R005 
 stop_gained 
 c.925C>T 
 p.Gln309Ter 
 Unknown 
 Not maternal 
  
 GEN472R006 
 stop_gained 
 c.1543C>T 
 p.Arg515Ter 
 De novo 
 NA 
  
 GEN472R007 
 frameshift_variant 
 c.705dup 
 p.Gly236ArgfsTer35 
 De novo 
 NA 
 Simplex 
 GEN472R008 
 stop_gained 
 c.1981C>T 
 p.Arg661Ter 
 De novo 
 NA 
 Simplex 
 GEN472R009 
 frameshift_variant 
 c.1041_1044del 
 p.Val349AlafsTer9 
 De novo 
 NA 
 Simplex 
 GEN472R010 
 frameshift_variant 
 c.998dup 
 p.Tyr333Ter 
 De novo 
 NA 
 Simplex 
 GEN472R011 
 stop_gained 
 c.1603C>T 
 p.Arg535Ter 
 De novo 
 NA 
 Simplex 
 GEN472R012 
 frameshift_variant 
 c.1690del 
 p.Val564SerfsTer6 
 De novo 
 NA 
 Simplex 
 GEN472R013 
 splice_site_variant 
 c.242-6T>G 
  
 De novo 
 NA 
  
 GEN472R014 
 frameshift_variant 
 c.1685del 
 p.Glu562GlyfsTer8 
 De novo 
 NA 
  
 GEN472R015 
 missense_variant 
 c.2255G>C 
 p.Gly752Ala 
 Unknown 
  
  
 GEN472R016 
 stop_gained 
 c.232C>T 
 p.Gln78Ter 
 De novo 
 NA 
 Simplex 
 GEN472R017 
 stop_gained 
 c.226C>T 
 p.Gln76Ter 
 Unknown 
  
  
 GEN472R018 
 stop_gained 
 c.1420C>T 
 p.Arg474Ter 
 De novo 
 NA 
  
 GEN472R019 
 stop_gained 
 c.607C>T 
 p.Gln203Ter 
 De novo 
 NA 
  
 GEN472R020 
 stop_gained 
 c.1420C>T 
 p.Arg474Ter 
 De novo 
 NA 
  
 GEN472R021 
 frameshift_variant 
 c.1925_1926del 
 p.Glu642GlyfsTer15 
 De novo 
 NA 
 Simplex 
 GEN472R022 
 stop_gained 
 c.1981C>T 
 p.Gln661Ter 
 De novo 
 NA 
 Simplex 
 GEN472R023 
 stop_gained 
 c.1801C>T 
 p.Gln601Ter 
 De novo 
 NA 
  
 GEN472R024 
 stop_gained 
 c.1603C>T 
 p.Arg535Ter 
 De novo 
 NA 
  
 GEN472R025 
 stop_gained 
 c.999C>G 
 p.Tyr333Ter 
 De novo 
 NA 
  
 GEN472R026 
 stop_gained 
 c.1420C>T 
 p.Arg474Ter 
 De novo 
 NA 
  
 GEN472R027 
 frameshift_variant 
 c.802_809del 
 p.Gly268AsnfsTer22 
 De novo 
 NA 
  
 GEN472R028 
 stop_gained 
 c.1612C>T 
 p.Gln538Ter 
 De novo 
 NA 
  
 GEN472R029 
 stop_gained 
 c.1420C>T 
 p.Arg474Ter 
 De novo 
 NA 
  
 GEN472R030 
 stop_gained 
 c.1672C>T 
 p.Arg558Cys 
 De novo 
 NA 
 Simplex 
 GEN472R031 
 frameshift_variant 
 c.1064_1067del 
 p.Pro355LeufsTer3 
 De novo 
 NA 
  
 GEN472R032 
 missense_variant 
 c.1127G>A 
 p.Arg376His 
 De novo 
 NA 
 Simplex 
 GEN472R033 
 missense_variant 
 c.1723G>A 
 p.Gly575Arg 
 De novo 
 NA 
  
 GEN472R034 
 stop_gained 
 c.1287C>A 
 p.Cys429Ter 
 Unknown 
  
 Extended multiplex 

Common

No Common Variants Available
Chromosome
CNV Locus
CNV Type
# of studies
Animal Model
3
Deletion
 13
 

Model Summary

This model specifically deletes CTNNB1 in parvalbumin interneurons.

References

Type
Title
Author, Year
Primary
Deletion of CTNNB1 in inhibitory circuitry contributes to autism-associated behavioral defects.

M_CTNNB1_1_CKO_HT_PVALBN

Model Type: Genetic
Model Genotype: Heterozygous
Mutation: Conditional deletion of exons 2-6 of CTNNB1 using Pvalb-Cre (parvalbumin-Cre) from parvalbumin positive interneurons
Allele Type: Conditional loss-of-function
Strain of Origin: 129/Sv
Genetic Background: 129/Sv
ES Cell Line:
Mutant ES Cell Line:
Model Source:

M_CTNNB1_1_CKO_HT_PVALBN

Category
Entity
Quantity
Experimental Paradigm
Age at Testing
Neuronal number: interneurons1
Increased
Description: Density of PV+ neurons in the prefrontal cortex was significantly higher in CTNNB1 cKO mice; However, the percentages of PV+ neurons in different hippocampal regions, the amygdala, and the hypothalamus were not changed suggesting the alteration is region-specific;
Exp Paradigm: CTNNB1 and Parvalbumin co- immunohistochemistry;
 Immunohistochemistry
 2 months
Neuronal activation1
Decreased
Description: In CTNNB1 cKO mice c-Fos staining was significantly reduced in the cortex, but not in the dentate gyrus and the amygdala, suggesting an increased inhibition in the cortex, which may contribute to CTNNB1 KO-mediated behavioral changes;
Exp Paradigm: c-FOS Immunohistochemistry
 Immunohistochemistry
 2 months
Self grooming: perseveration1
Increased
Description: CTNNB1 cKO mice had significantly more grooming time than their control littermates
Exp Paradigm: Measured the total grooming time in a testing session of 25 minutes
 Grooming behavior assessments
 2 months
Head bobbing1
Increased
Description: CKO mice significantly increased their head-dipping behavior especially at the center region of the plus maze apparatus
Exp Paradigm: Elevated plus maze test
 Elevated plus maze test
 2 months
Social interaction1
Decreased
Description: When presented with an unfamiliar mouse, CTNNB1flox/flox mice preferred to interact with the unfamiliar mouse with higher interacting time and frequency; PV-Cre; CTNNB1flox/flox mice failed to show social novelty behavior;
Exp Paradigm: Three-chamber social approach test;
 Three-chamber social approach test
 2 months
Nest building behavior1
Decreased
Description: PV-Cre; CTNNB1flox/flox mice performed worse on nest building test than control mice at 1 or 24 hours after setting up the nesting;
Exp Paradigm: Nest building assay;
 Nest building assay
 2 months
Anxiety1
Increased
Description: Significant decreases detected on center duration time, center distance traveled, frequency and increased latency of center entry; It took much longer for CTNNB1 cKO mice to enter open arms;
Exp Paradigm: Open field test; Elevated plus maze test;-Open field test
 Open field test
 2 months
Anxiety1
Increased
Description: Significant decreases detected on center duration time, center distance traveled, frequency and increased latency of center entry; It took much longer for CTNNB1 cKO mice to enter open arms;
Exp Paradigm: Open field test; Elevated plus maze test;- Elevated plus maze test
 Elevated plus maze test
 2 months
Cued or contextual fear conditioning: memory of cue: long term recall1
Decreased
Description: Memory extinction was impaired as new memories cannot be formed in CTNNB1 cKO mice;
Exp Paradigm: Fear conditioning test
 Fear conditioning test
 2 months
Spatial learning1
Increased
Description: Within 4 training days, CTNNB1 cKO mice took less time and swam shorter distances to reach the platform; They also showed a higher percentage of successful rate of finding the hidden-platform within 60 seconds; These indicate PV-Cre; CTNNB1flox/flox mice can memorize the position of the platform in relation to spatial cues with higher accuracy;
Exp Paradigm: Morris water maze test;
 Morris water maze test
 2 months
Object recognition memory1
Decreased
Description: After 24 hours, the animals were retested when novel object 1 was paired with novel object 2; control mice spent significantly more time with the novel object 2 suggesting that they retained long-term memory; However, PV-Cre; CTNNB1flox/flox mice had similar interactive durations and frequencies between novel object 2 and the familiar object; The NOR test indicated that CTNNB1 cKO from PV+ neurons affected the long-term recognition but not the short-term memory;
Exp Paradigm: Novel object recognition test;
 Novel object recognition test
 2 months
Targeted expression1
Decreased
Description: CTNNB1 expressions was deleted in almost all PV+ neurons
Exp Paradigm: CTNNB1 and Parvalbumin co- immunohistochemistry;
 Immunohistochemistry
 2 months
Depression1
 No change
 Tail suspension test
 2 months
Cued or contextual fear conditioning1
 No change
 Fear conditioning test
 2 months
Object recognition memory1
 No change
 Novel object recognition test
 2 months
General locomotor activity1
 No change
 Open field test
 2 months
Motor coordination and balance1
 No change
 Accelerating rotarod test
 2 months
Rearing behavior1
 No change
 Elevated plus maze test
 2 months
Neuronal number: interneurons1
 No change
 Immunohistochemistry
 3 weeks
Stereotypy1
 No change
 Marble-burying test
 2 months
 Not Reported: Circadian sleep/wake cycle, Communications, Developmental profile, Immune response, Maternal behavior, Physiological parameters, Seizure, Sensory


Interactor Symbol Interactor Name Interactor Organism Entrez ID Uniprot ID Interaction Type Evidence Reference
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 25 P00519 IP/WB; Y2H; High-throughput fluorescence polarization interaction analysis assay
Chen R , et al. 2013
AHR aryl hydrocarbon receptor 196 P35869 IP/WB; GST; High-throughput fluorescence polarization interaction analysis assay
Kawajiri K , et al. 2009
AJAP1 Adherens junction-associated protein 1 55966 Q9UKB5 IP/WB; GST; High-throughput fluorescence polarization interaction analysis assay
Bharti S , et al. 2003
AKT1 v-akt murine thymoma viral oncogene homolog 1 207 P31749 Biochemical activity; IP/WB; MS/MS; High-throughput fluorescence polarization interaction analysis assay
Tian Q , et al. 2004
AMOT angiomotin 154796 Q4VCS5 MS; LC-MS/MS; High-throughput fluorescence polarization interaction analysis assay
Couzens AL , et al. 2013
APC adenomatous polyposis coli 324 P25054 X-ray crystallography; GST; IP/WB; High-throughput fluorescence polarization interaction analysis assay
Xing Y , et al. 2004
APC adenomatous polyposis coli 324 P25054 IP/WB
Cai J , et al. 2015
APC adenomatous polyposis coli 324 P25054 IP/WB; in vitro binding assay; Peptide mapping
Su LK , et al. 1993
APC2 adenomatosis polyposis coli 2 10297 O95996 IP/WB
Schneikert J , et al. 2013
APP amyloid beta (A4) precursor protein 351 P05067 Reconstituted complex; ProtoArray; High-throughput fluorescence polarization interaction analysis assay
Olh J , et al. 2011
AR androgen receptor 367 P10275 IP/WB; GST; High-throughput fluorescence polarization interaction analysis assay
Amir AL , et al. 2003
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 9070 Q9UBL3 Reconstituted complex; GST; IP/WB; High-throughput fluorescence polarization interaction analysis assay
Sierra J , et al. 2006
ATF2 activating transcription factor 2 1386 P15336 MS
Lau E , et al. 2012
AXIN1 axin 1 8312 O15169 IP/WB; Nano-LC/MS/MS; High-throughput fluorescence polarization interaction analysis assay
Fei C , et al. 2013
AXIN1 axin 1 8312 O15169 IP; LC-MS/MS; IP/WB
Yu N , et al. 2015
BCL3 B-cell CLL/lymphoma 3 602 P20749 IP/WB
Kim JH , et al. 2005
BOC BOC cell adhesion associated, oncogene regulated 91653 Q96DN7 IP/WB
Kang JS , et al. 2003
BRCA1 breast cancer 1, early onset 672 P38398 IP/WB; GST; High-throughput fluorescence polarization interaction analysis assay
Li H , et al. 2010
BTF3 basic transcription factor 3 689 P20290 MS; IP/WB; MS/MS; High-throughput fluorescence polarization interaction analysis assay
Tian Q , et al. 2004
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 8945 B2R8L3 IP/WB
Chen CH , et al. 2012
C6ORF26 Suppressor APC domain-containing protein 1 401251 Q5SSQ6-2 IP; LC-MS/MS
Huttlin EL , et al. 2015
CA9 Carbonic anhydrase 9 768 Q16790 IP/WB
Svastov E , et al. 2003
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit 8913 O43497 Luciferase reporter assay
Wisniewska MB , et al. 2010
CAV1 caveolin 1, caveolae protein, 22kDa 857 Q03135 IP/WB
Conde-Perez A , et al. 2015
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 867 P22681 Biochemical activity; in vitro ubiquitination assay; IP/WB; High-throughput fluorescence polarization interaction analysis assay
Chitalia V , et al. 2013
CBY1 Protein chibby homolog 1 25776 Q9Y3M2 IP/WB; GST; High-throughput fluorescence polarization interaction analysis assay
Takemaru K , et al. 2003
CCNA1 Cyclin-A1 8900 P78396 IP/WB; GST; High-throughput fluorescence polarization interaction analysis assay
Park CS , et al. 2004
CCNA2 cyclin A2 890 P20248 Reconstituted complex; GST; IP/WB; High-throughput fluorescence polarization interaction analysis assay
Park CS , et al. 2004
CCNE1 cyclin E1 898 P24864 IP/WB; GST; High-throughput fluorescence polarization interaction analysis assay
Park CS , et al. 2004
CDC27 cell division cycle 27 996 G3V1C4 Reconstituted complex; MS; IP/WB; ChIP; High-throughput fluorescence polarization interaction analysis assay
Sierra J , et al. 2006
CDC73 cell division cycle 73 79577 Q6P1J9 IP/WB; MS; High-throughput fluorescence polarization interaction analysis assay
Takahashi A , et al. 2011
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 999 P12830 IP/WB
Smyth D , et al. 2012
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 999 P12830 IP/WB
Decarlo L , et al. 2015
CDH10 cadherin 10, type 2 (T2-cadherin) 1008 Q9Y6N8 IP/WB
Shimoyama Y , et al. 2000
CDH11 Cadherin-11 1009 P55287 IP/WB
Langhe RP , et al. 2016
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 1000 P19022 MS; IP/WB; High-throughput fluorescence polarization interaction analysis assay
Straub BK , et al. 2003
cdh3-b Beta-catenin-interacting protein 1 594865 Q9NSA3 GST; IP/WB
Graham TA , et al. 2002
CDH5 Cadherin-5 1003 P33151 IP/WB
Margariti A , et al. 2010
CDH5 Cadherin-5 1003 P33151 IP; LC-MS/MS
Huttlin EL , et al. 2015
CDH8 cadherin 8, type 2 1006 P55286 IP; LC-MS/MS
Huttlin EL , et al. 2015
CDH9 Cadherin-9 1007 Q9ULB4 IP/WB
Shimoyama Y , et al. 2000
CDK2 cyclin-dependent kinase 2 1017 P24941 GST; IP/WB; High-throughput fluorescence polarization interaction analysis assay
Park CS , et al. 2004
CDON cell adhesion associated, oncogene regulated 50937 Q4KMG0 IP/WB
Kang JS , et al. 2003
CEBPA CCAAT/enhancer-binding protein zeta 12606 P53569 IP/WB
Kennell JA , et al. 2003
CHD8 chromodomain helicase DNA binding protein 8 57680 Q9HCK8 GST; ChIP-chip
Thompson BA , et al. 2008
CHD8 chromodomain helicase DNA binding protein 8 57680 Q9HCK8 ChIP; IP/WB; High-throughput fluorescence polarization interaction analysis assay
Nishiyama M , et al. 2011
CHUK conserved helix-loop-helix ubiquitous kinase 1147 O15111 IP/WB; GST; High-throughput fluorescence polarization interaction analysis assay
Lamberti C , et al. 2001
COPS3 COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis) 8533 Q9UNS2 GST; IP/WB; High-throughput fluorescence polarization interaction analysis assay
Huang X , et al. 2009
COPS5 COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) 10987 Q92905 GST; IP/WB; High-throughput fluorescence polarization interaction analysis assay
Huang X , et al. 2009
COPS8 COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) 10920 Q53QS9 GST; IP/WB; High-throughput fluorescence polarization interaction analysis assay
Huang X , et al. 2009
CREBBP CREB binding protein 1387 Q92793 GST; IP/WB; High-throughput fluorescence polarization interaction analysis assay
Sustmann C , et al. 2008
CRYAB Alpha-crystallin B chain 1410 P02511 IP/WB
Ghosh JG , et al. 2007
CSNK1D casein kinase 1, delta 64462 Q06486 in vitro kinase assay
Amit S , et al. 2002
CTBP1 C-terminal binding protein 1 1487 Q13363 GST; IP/WB; High-throughput fluorescence polarization interaction analysis assay
Hamada F and Bienz M 2004
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 1495 P35221 MS
Selbach M and Mann M 2006
CTNNA3 catenin (cadherin-associated protein), alpha 3 29119 A8K141 MS; Y2H; High-throughput fluorescence polarization interaction analysis assay
Waaijers S , et al. 2013
CTNNA3 catenin (cadherin-associated protein), alpha 3 29119 A8K141 IP; LC-MS/MS
Huttlin EL , et al. 2015
CTNNBIP1 Beta-catenin-interacting protein 1 56998 Q9NSA3 MS
Selbach M and Mann M 2006
CTNNBIP1 Beta-catenin-interacting protein 1 56998 Q9NSA3 IP; LC-MS/MS
Huttlin EL , et al. 2015
CTNND1 catenin (cadherin-associated protein), delta 1 1500 O60716 GST; IP/WB; High-throughput fluorescence polarization interaction analysis assay
Kucerov D , et al. 2001
CTNND2 catenin (cadherin-associated protein), delta 2 1501 Q9UQB3 IP/WB
Turner TN , et al. 2015
CUL3 cullin 3 8452 B7Z600 MS; LC-MS/MS; High-throughput fluorescence polarization interaction analysis assay
Bennett EJ , et al. 2010
CUL4A cullin 4A 8451 Q13619 IP/WB
Tripathi R , et al. 2007
DDB1 damage-specific DNA binding protein 1, 127kDa 1642 Q16531 IP/WB; GST; High-throughput fluorescence polarization interaction analysis assay
Kawajiri K , et al. 2009
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 1653 A3RJH1 MS
Sato S , et al. 2005
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 1655 P17844 IP/WB
Sato S , et al. 2005
DHX9 DEAH (Asp-Glu-Ala-His) box polypeptide 9 1660 Q08211 MS
Sato S , et al. 2005
DLG5 discs, large homolog 5 (Drosophila) 9231 Q8TDM6 IP/WB; Y2H; GST; High-throughput fluorescence polarization interaction analysis assay
Wakabayashi M , et al. 2003
EGFR epidermal growth factor receptor 1956 P00533 IP/WB
Schroeder JA , et al. 2002
ELAVL1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) 1994 Q15717 Reconstituted complex; RNP IP; IP/WB; High-throughput fluorescence polarization interaction analysis assay
Kim I , et al. 2012
EMD emerin 2010 P50402 IP/WB
Markiewicz E , et al. 2006
EP300 E1A binding protein p300 2033 Q9Y6B2 IP/WB
Kennell JA , et al. 2003
EP400 E1A binding protein p400 57634 Q96L91 MS
Sierra J , et al. 2006
EPAS1 endothelial PAS domain protein 1 2034 Q99814 MS; Nano-LC/MS/MS; High-throughput fluorescence polarization interaction analysis assay
Steunou AL , et al. 2013
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 2064 P04626 IP/WB
Schroeder JA , et al. 2002
ERBB2IP erbb2 interacting protein 55914 Q96RT1 Protein-peptide; Peptide microarray; High-throughput fluorescence polarization interaction analysis assay
Boisguerin P , et al. 2004
ESR1 estrogen receptor 1 2099 P03372 IP/WB; ChIP; High-throughput fluorescence polarization interaction analysis assay
Kouzmenko AP , et al. 2004
EZH2 enhancer of zeste homolog 2 (Drosophila) 2146 Q15910 IP/WB
Li X , et al. 2009
FAF1 Fas (TNFRSF6) associated factor 1 11124 Q9UNN5 IP/WB
Zhang L , et al. 2011
FAM123B APC membrane recruitment protein 1 139285 Q5JTC6 Reconstituted complex; GST; IP/WB; High-throughput fluorescence polarization interaction analysis assay
Major MB , et al. 2007
FANCC Fanconi anemia, complementation group C 2176 Q00597 IP/WB; Ubiquitination assay; High-throughput fluorescence polarization interaction analysis assay
Dao KH , et al. 2012
FANCL Fanconi anemia, complementation group L 55120 Q9NW38 IP/WB; Ubiquitination assay; High-throughput fluorescence polarization interaction analysis assay
Dao KH , et al. 2012
FBXW11 F-box and WD repeat domain containing 11 23291 Q9UKB1 MS; GST; High-throughput fluorescence polarization interaction analysis assay
Gao D , et al. 2011
FHIT fragile histidine triad gene 2272 P49789 IP/WB
Weiske J , et al. 2007
FHL2 four and a half LIM domains 2 2274 Q14192 Y2H; IP/WB; GST; High-throughput fluorescence polarization interaction analysis assay
Wei Y , et al. 2002
FOXO3 forkhead box O3 2309 O43524 IP/WB; Y2H; High-throughput fluorescence polarization interaction analysis assay
Essers MA , et al. 2005
FOXO4 forkhead box O4 4303 P98177 IP/WB
Essers MA , et al. 2005
FUS fused in sarcoma 2521 P35637 Y2H; IP/WB
Sato S , et al. 2005
GEMIN5 gem (nuclear organelle) associated protein 5 25929 B7ZLC9 MS
Sato S , et al. 2005
GLIS2 Zinc finger protein GLIS2 84662 Q9BZE0 IP/WB; Y2H; M2H; GST; High-throughput fluorescence polarization interaction analysis assay
Kim YS , et al. 2007
GRIP1 glutamate receptor interacting protein 1 23426 Q9Y3R0 Phenotypic enhancement; GST; IP/WB; High-throughput fluorescence polarization interaction analysis assay
Song LN and Gelmann EP 2005
GRIP1 glutamate receptor interacting protein 1 23426 Q9Y3R0 Phenotypic enhancement
Lee YH and Stallcup MR 2006
GSK3B glycogen synthase kinase 3 beta 2932 P49841 MS; AP-MS; IP/WB; Bimolecular fluorescence complementation assay; High-throughput fluorescence polarization interaction analysis assay
Varjosalo M , et al. 2013
HDAC2 histone deacetylase 2 3066 Q92769 Negative genetic; GST; In vivo acetylation assay; in vitro kinase assay; AMPK kinase assay; IP/WB; High-throughput fluorescence polarization interaction analysis assay
Lin YY , et al. 2012
HDAC4 histone deacetylase 4 9759 P56524 IP/WB
Vietor I , et al. 2005
HDAC6 histone deacetylase 6 10013 Q9UBN7 Biochemical activity
Li Y , et al. 2008
HDAC7 histone deacetylase 7 51564 Q8WUI4 IP/WB
Margariti A , et al. 2010
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 51191 B4DXV3 IP/WB
Lee JH , et al. 2010
HINT1 histidine triad nucleotide binding protein 1 3094 P49773 IP/WB
Genovese G , et al. 2012
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 3178 P09651 IP/WB
Sato S , et al. 2005
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 3181 P22626 MS
Sato S , et al. 2005
HNRNPK heterogeneous nuclear ribonucleoprotein K 3190 P61978 IP/WB
Sato S , et al. 2005
HNRNPM heterogeneous nuclear ribonucleoprotein M 4670 P52272 MS
Sato S , et al. 2005
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 3326 P08238 MS; IP/WB; MS/MS; High-throughput fluorescence polarization interaction analysis assay
Tian Q , et al. 2004
HSPA1B heat shock 70kDa protein 1B 3304 A8K5I0 MS; IP/WB; MS/MS; High-throughput fluorescence polarization interaction analysis assay
Tian Q , et al. 2004
HSPA8 heat shock 70kDa protein 8 3312 P11142 MS; IP/WB; MS/MS; High-throughput fluorescence polarization interaction analysis assay
Tian Q , et al. 2004
HTT Huntingtin 3064 P42858 IP/WB
Godin JD , et al. 2010
IFRD1 Interferon-related developmental regulator 1 15982 P19182 IP/WB
Vietor I , et al. 2005
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 3551 O14920 GST; IP/WB; High-throughput fluorescence polarization interaction analysis assay
Lamberti C , et al. 2001
IQGAP1 IQ motif containing GTPase activating protein 1 8826 P46940 Reconstituted complex; IP/WB; High-throughput fluorescence polarization interaction analysis assay
Briggs MW , et al. 2001
ISG15 ISG15 ubiquitin-like modifier 9636 P05161 IP/WB
Lee JH , et al. 2010
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 3675 P26006 IP/WB
Decarlo L , et al. 2015
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 3688 P05556 IP/WB
Decarlo L , et al. 2015
JUP junction plakoglobin 3728 P14923 IP/WB; GST; High-throughput fluorescence polarization interaction analysis assay
Kucerov D , et al. 2001
KAT2A K(lysine) acetyltransferase 2A 2648 Q92830 ChIP; GST; IP/WB; High-throughput fluorescence polarization interaction analysis assay
Chen J , et al. 2010
KAT2B K(lysine) acetyltransferase 2B 8850 Q92831 IP/WB
Ge X , et al. 2008
LATS2 LATS, large tumor suppressor, homolog 2 (Drosophila) 26524 Q9NRM7 MS; LC-MS/MS; High-throughput fluorescence polarization interaction analysis assay
Couzens AL , et al. 2013
LDHB lactate dehydrogenase B 3945 P07195 MS; IP/WB; MS/MS; High-throughput fluorescence polarization interaction analysis assay
Tian Q , et al. 2004
LEF1 lymphoid enhancer-binding factor 1 51176 Q659G9 IP/WB; Proximity ligation assay
Jamieson C , et al. 2015
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 9208 E9PGZ2 IP/WB; GST; High-throughput fluorescence polarization interaction analysis assay
Lee YH and Stallcup MR 2006
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 9863 Q86UL8 GST; IP/WB
Xu J , et al. 2001
MAPK8 mitogen-activated protein kinase 8 5599 P45983 IP/WB; Nano-LC/MS/MS; GST; High-throughput fluorescence polarization interaction analysis assay
Lee MH , et al. 2009
MAPK9 mitogen-activated protein kinase 9 5601 P45984 IP/WB; Nano-LC/MS/MS; GST; High-throughput fluorescence polarization interaction analysis assay
Lee MH , et al. 2009
MEN1 multiple endocrine neoplasia I 4221 O00255 Reconstituted complex
Chen G , et al. 2008
MET met proto-oncogene (hepatocyte growth factor receptor) 4233 P08581 IP/WB
Davies G , et al. 2001
MICAL-L2 MICAL-like protein 2 79778 Q8IY33 qRT-PCR; Immunohistochemistry; Immunofluorescence; Expression microarray; IP/WB
Zhu LY , et al. 2015
MLL lysine (K)-specific methyltransferase 2A 4297 Q03164 MS
Sierra J , et al. 2006
MLL2 lysine (K)-specific methyltransferase 2D 8085 O14686 Reconstituted complex; MS; IP/WB; High-throughput fluorescence polarization interaction analysis assay
Sierra J , et al. 2006
MUC1 mucin 1, cell surface associated 4582 P15941 Reconstituted complex; GST; IP/WB; High-throughput fluorescence polarization interaction analysis assay
Li Y , et al. 2003
NDRG1 N-myc downstream regulated 1 10397 Q92597 MS
Tu LC , et al. 2007
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 4790 P19838 ChIP; IP/WB
Kim JH , et al. 2005
NLK nemo-like kinase 51701 Q9UBE8 IP/WB
Ishitani T , et al. 2003
NONO non-POU domain containing, octamer-binding 4841 Q15233 MS
Sato S , et al. 2005
NOTCH1 notch 1 4851 P46531 IP/WB; Reconstituted complex; High-throughput fluorescence polarization interaction analysis assay
Jin YH , et al. 2008
NR4A1 Nuclear receptor subfamily 4 group A member 1 3164 P22736 IP/WB; Ubiquitination assay; High-throughput fluorescence polarization interaction analysis assay
Sun Z , et al. 2011
NR5A1 nuclear receptor subfamily 5, group A, member 1 26423 P33242 IP/WB
Kennell JA , et al. 2003
NUP153 nucleoporin 153kDa 9972 P49790 MS; IP/WB; FRAP; High-throughput fluorescence polarization interaction analysis assay
Sharma M , et al. 2011
NUP62 nucleoporin 62kDa 23636 P37198 IP/WB; MS; FRAP; High-throughput fluorescence polarization interaction analysis assay
Sharma M , et al. 2011
NUP98 nucleoporin 98kDa 4928 P52948 MS; IP/WB; FRAP; High-throughput fluorescence polarization interaction analysis assay
Sharma M , et al. 2011
PARP1 poly (ADP-ribose) polymerase 1 142 P09874 MS
Sato S , et al. 2005
PCDH9 protocadherin 9 5101 Q9HC56 ChIP
Pedrosa E , et al. 2010
PHB2 prohibitin 2 11331 Q99623 MS; LC/ESI/MS/MS; Y2H; High-throughput fluorescence polarization interaction analysis assay
Ewing RM , et al. 2007
PHF17 PHD finger protein 17 79960 Q6IE81 IP/WB; Y2H; GST; High-throughput fluorescence polarization interaction analysis assay
Chitalia VC , et al. 2008
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 5300 Q13526 Reconstituted complex; GST; IP/WB; High-throughput fluorescence polarization interaction analysis assay
Ryo A , et al. 2001
PITX2 paired-like homeodomain 2 5308 Q99697 IP/WB; ChIP
Kioussi C , et al. 2002
PLK1 polo-like kinase 1 5347 P53350 MS; GST; MS/MS; High-throughput fluorescence polarization interaction analysis assay
Lin DC , et al. 2011
PML promyelocytic leukemia 5371 P29590 IP/WB; MS; High-throughput fluorescence polarization interaction analysis assay
Satow R , et al. 2011
PROP1 Homeobox protein prophet of Pit-1 5626 O75360 IP/WB; ChIP; GST; High-throughput fluorescence polarization interaction analysis assay
Olson LE , et al. 2006
PRPF6 PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae) 24148 O94906 MS
Sato S , et al. 2005
PSEN1 presenilin 1 5663 P49768 IP/WB; GST; High-throughput fluorescence polarization interaction analysis assay
Prager K , et al. 2007
PTEN phosphatase and tensin homolog 5728 F6KD01 IP/WB
Vogelmann R , et al. 2005
PTGS2 Prostaglandin G/H synthase 2 5743 P35354 Protein-RNA; RNP IP; IP/WB; High-throughput fluorescence polarization interaction analysis assay
Kim I , et al. 2012
PTPN1 protein tyrosine phosphatase, non-receptor type 1 5770 P18031 Reconstituted complex; IP/WB; GST; High-throughput fluorescence polarization interaction analysis assay
Xu G , et al. 2002
PTPN14 protein tyrosine phosphatase, non-receptor type 14 5784 A8K6H6 MS; ChIP; High-throughput fluorescence polarization interaction analysis assay
Wadham C , et al. 2003
PTPRJ protein tyrosine phosphatase, receptor type, J 5795 Q12913 IP/WB; GST; High-throughput fluorescence polarization interaction analysis assay
Holsinger LJ , et al. 2002
PTPRU protein tyrosine phosphatase, receptor type, U 10076 Q92729 IP/WB
Yan HX , et al. 2006
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 5879 P63000 IP/WB; Proximity ligation assay
Jamieson C , et al. 2015
RANBP2 RAN binding protein 2 5903 P49792 IP/WB; MS; FRAP; High-throughput fluorescence polarization interaction analysis assay
Sharma M , et al. 2011
RB1CC1 RB1-inducible coiled-coil 1 9821 Q8TDY2 IP/WB; Y2H; High-throughput fluorescence polarization interaction analysis assay
Choi JD , et al. 2012
RBBP5 retinoblastoma binding protein 5 5929 Q15291 IP/WB; ChIP; GST; High-throughput fluorescence polarization interaction analysis assay
Chen J , et al. 2010
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 54715 Q9NWB1 qRT-PCR; IP/WB; in situ hybridization; in silico target prediction
Fogel BL , et al. 2012
RBMX RNA binding motif protein, X-linked 27316 P38159 MS
Sato S , et al. 2005
RPLP2 ribosomal protein, large, P2 6181 P05387 MS; IP/WB; MS/MS; High-throughput fluorescence polarization interaction analysis assay
Tian Q , et al. 2004
RPSA ribosomal protein SA 3921 P08865 MS; IP/WB; MS/MS; High-throughput fluorescence polarization interaction analysis assay
Tian Q , et al. 2004
RUVBL1 RuvB-like 1 (E. coli) 8607 Q9Y265 MS
Sierra J , et al. 2006
RUVBL2 RuvB-like 2 (E. coli) 10856 Q9Y230 High-throughput fluorescence polarization interaction analysis assay; ChIP; GST; IP/WB; Y2H
Bauer A , et al. 2000
RXRA retinoid X receptor, alpha 6256 F1D8Q5 IP/WB
Xiao JH , et al. 2003
RYK receptor-like tyrosine kinase 6259 P34925 MS; AP-MS/MS; High-throughput fluorescence polarization interaction analysis assay
Berndt JD , et al. 2011
SATB1 SATB homeobox 1 6304 Q01826 IP/WB; ChIP; High-throughput fluorescence polarization interaction analysis assay
Notani D , et al. 2010
SERBP1 SERPINE1 mRNA binding protein 1 26135 Q8NC51 MS; IP/WB; MS/MS; High-throughput fluorescence polarization interaction analysis assay
Tian Q , et al. 2004
SIAH1 seven in absentia homolog 1 (Drosophila) 6477 Q8IUQ4 Biochemical activity; in vitro ubiquitination assay; High-throughput fluorescence polarization interaction analysis assay
Dimitrova YN , et al. 2010
SIRT1 sirtuin 1 23411 A8K128 IP/WB
Holloway KR , et al. 2010
SKP1 S-phase kinase-associated protein 1 6500 P63208 IP/WB
Wang D , et al. 2011
SLAMF7 SLAM family member 7 57823 Q9NQ25-3 IP; LC-MS/MS
Huttlin EL , et al. 2015
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 9368 O14745 IP/WB
Shibata T , et al. 2003
SMAD2 SMAD family member 2 4087 Q15796 IP/WB
Decarlo L , et al. 2015
SMAD3 SMAD family member 3 4088 P84022 IP/WB; ChIP; High-throughput fluorescence polarization interaction analysis assay
Zhou B , et al. 2012
SMAD3 SMAD family member 3 4088 P84022 IP/WB
Decarlo L , et al. 2015
SMAD4 SMAD family member 4 4089 Q13485 IP/WB
Tian YC and Phillips AO 2002
SMAD7 SMAD family member 7 4092 K7EQ10 IP/WB
Tang Y , et al. 2008
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 6597 A7E2E1 Y2H; IP/WB
Barker N , et al. 2001
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 8467 O60264 MS
Sierra J , et al. 2006
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa 6632 P62314 MS; IP/WB; MS/MS; High-throughput fluorescence polarization interaction analysis assay
Tian Q , et al. 2004
SOX2 Transcription factor SOX-2 6657 P48431 MS; IP/WB; High-throughput fluorescence polarization interaction analysis assay
Cox JL , et al. 2013
SOX6 SRY (sex determining region Y)-box 6 55553 P35712 IP/WB
Iguchi H , et al. 2007
STRN3 striatin, calmodulin binding protein 3 29966 Q13033 MS; LC-MS/MS; High-throughput fluorescence polarization interaction analysis assay
Couzens AL , et al. 2013
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 6839 O43463 IP/WB; MS; High-throughput fluorescence polarization interaction analysis assay
Takahashi A , et al. 2011
TADA2A transcriptional adaptor 2A 6871 O75478 IP/WB
Yang M , et al. 2007
TADA3 transcriptional adaptor 3 10474 O75528 IP/WB
Yang M , et al. 2007
TAX1BP3 Tax1-binding protein 3 30851 Q9DBG9 X-ray crystallography
Zhang J , et al. 2008
TBL1X transducin (beta)-like 1X-linked 6907 O60907 ChIP; IP/WB; High-throughput fluorescence polarization interaction analysis assay
Li J and Wang CY 2008
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 79718 Q9BZK7 IP/WB; ChIP; High-throughput fluorescence polarization interaction analysis assay
Li J and Wang CY 2008
TCF3 transcription factor 3 6929 P15923 IP/WB
Sato S , et al. 2005
TCF4 transcription factor 4 6925 B3KVA4 X-ray crystallography
Graham TA , et al. 2001
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 6934 Q9NQB0 IP/WB; in vitro binding assay
Tzeng SL , et al. 2006
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 6934 Q9NQB0 GST; IP/WB; ChIP; High-throughput fluorescence polarization interaction analysis assay
Del Valle-Prez B , et al. 2011
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 7020 P05549 IP/WB; GST; High-throughput fluorescence polarization interaction analysis assay
Li Q and Dashwood RH 2004
TGFBR1 transforming growth factor, beta receptor 1 7046 P36897 IP/WB
Decarlo L , et al. 2015
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 7048 P37173 IP/WB
Tian YC and Phillips AO 2002
TIP60 Histone acetyltransferase KAT5 10524 Q92993 ChIP; IP/WB
Kim JH , et al. 2005
TOB1 transducer of ERBB2, 1 10140 P50616 Y2H; IP/WB; High-throughput fluorescence polarization interaction analysis assay
Xiong B , et al. 2006
TOP2A topoisomerase (DNA) II alpha 170kDa 7153 P11388 IP/WB
Sato S , et al. 2005
TOP3B topoisomerase (DNA) III beta 8940 O95985 HITS-CLIP
Xu D , et al. 2013
TRRAP transformation/transcription domain-associated protein 8295 Q9Y4A5 IP/WB; GST; High-throughput fluorescence polarization interaction analysis assay
Sustmann C , et al. 2008
TSC1 tuberous sclerosis 1 7248 Q92574 Y2H
Sakai Y , et al. 2011
TUBA1A tubulin, alpha 1A 7846 Q71U36 MS; IP/WB; MS/MS; High-throughput fluorescence polarization interaction analysis assay
Tian Q , et al. 2004
UBC ubiquitin C 7316 P63279 IP/WB
Chen CH , et al. 2012
UBE2B ubiquitin-conjugating enzyme E2B 7320 P63146 IP/WB; Ubiquitination assay; High-throughput fluorescence polarization interaction analysis assay
Gerard B , et al. 2012
UBE2D1 ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) 7321 P51668 Reconstituted complex; IP/WB; High-throughput fluorescence polarization interaction analysis assay
Saha A and Deshaies RJ 2008
UHRF2 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase 115426 Q96PU4 Far Western Blot; GST; IP/WB; High-throughput fluorescence polarization interaction analysis assay
Mori T , et al. 2011
VCL vinculin 7414 B3KXA2 IP/WB
Hazan RB , et al. 1998
WHSC1 Wolf-Hirschhorn syndrome candidate 1 7468 O96028 ChIP; IP/WB; High-throughput fluorescence polarization interaction analysis assay
Toyokawa G , et al. 2011
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 7534 P63104 IP/WB
Chen CH , et al. 2012
ZBTB33 zinc finger and BTB domain containing 33 10009 Q86T24 Reconstituted complex; GST; IP/WB; High-throughput fluorescence polarization interaction analysis assay
Del Valle-Prez B , et al. 2011
ZFYVE9 zinc finger, FYVE domain containing 9 9372 O95405 Y2H
Colland F , et al. 2004
ACP1 Low molecular weight phosphotyrosine protein phosphatase 11431 Q9D358 GST; IP/WB
Taddei ML , et al. 2002
Akt1 thymoma viral proto-oncogene 1 11651 P31750 qRT-PCR; IP/WB; Luciferase reporter assay; Immunofluorescence
Luo W , et al. 2015
Bcl9l B-cell CLL/lymphoma 9-like 80288 Q67FY2 GST; Y2H; IP/WB
Adachi S , et al. 2004
CDH8 Cadherin-8 O54800 IP/WB
Kido M , et al. 1998
CTNND2 catenin (cadherin associated protein), delta 2 18163 O35927 IP/WB
Bareiss S , et al. 2010
FER fer (fps/fes related) tyrosine kinase 2241 P16591 GST; IP/WB; in vitro kinase assay
Piedra J , et al. 2003
FMR1 fragile X mental retardation 1 14265 P35922 HITS-CLIP
Darnell JC , et al. 2011
FYN FYN oncogene related to SRC, FGR, YES 2534 P06241 GST; IP/WB; in vitro kinase assay
Piedra J , et al. 2003
GRIK2 glutamate receptor, ionotropic, kainate 2 54257 P42260 IP/WB; GST
Coussen F , et al. 2002
HDAC1 Histone deacetylase 1 433759 O09106 ChIP; IP/WB
Iioka H , et al. 2009
LEF1 Lymphoid enhancer-binding factor 1 16842 P27782 IP/WB
Feigin ME and Malbon CC 2008
MET met proto-oncogene 17295 P16056 IP/WB
Monga SP , et al. 2002
MET met proto-oncogene 17295 P16056 IP; LC-MS/MS
Xie Z , et al. 2016
Pax6 paired box gene 6 18508 P63015 Luciferase reporter assay
Hsu LC , et al. 2015
SMAD2 Mothers against decapentaplegic homolog 2 17126 Q62432 ChIP; IP/WB
Dahle , et al. 2010
TCF7L2 Trinucleotide repeat-containing gene 6B protein 213988 Q8BKI2 IP/WB
Zhao C , et al. 2016
FAT1 FAT tumor suppressor homolog 1 (Drosophila) 83720 Q9WU10 IP/WB
Hou R , et al. 2006
CALCOCO1 calcium binding and coiled-coil domain 2 419993 E1BRX6 IP/WB
Yang CK , et al. 2006
CARM1 coactivator-associated arginine methyltransferase 1 59035 Q9WVG6 IP/WB; GST
Koh SS , et al. 2002
CTNND2 catenin (cadherin-associated protein), delta 2 1501 Q9UQB3 IP/WB; Co-localization
Lu Q , et al. 1999

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