HELP     Sign In
Search

Relevance to Autism

This gene has been associated with syndromic autism, where a subpopulation of individuals with a given syndrome develop autism. In particular, rare mutations of the CHD7 gene have been identified with CHARGE syndrome (Vissers et al., 2004), and a rare mutation in the CHD7 gene has been identified in an individual with ASD (ORoak et al., 2012).

Molecular Function

This gene encodes a protein that contains several helicase family domains. Mutations in this gene have been found in some patients with the CHARGE syndrome.

External Links

        

References

Type
Title
Type of Disorder
Associated Disorders
Author, Year
Primary
Mutations in a new member of the chromodomain gene family cause CHARGE syndrome.
CHARGE syndrome
ASD
Support
Trio-based exome sequencing reveals a high rate of the de novo variants in intellectual disability
ASD, ADHD, ID
Support
Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder
ASD
Support
CHARGE syndrome
Support
Inherited and multiple de novo mutations in autism/developmental delay risk genes suggest a multifactorial model.
ASD
Support
Detection of clinically relevant genetic variants in autism spectrum disorder by whole-genome sequencing.
ASD
Support
Exome sequencing improves the molecular diagnostics of paediatric unexplained neurodevelopmental disorders
ID
Support
CHARGE syndrome protein CHD7 regulates epigenomic activation of enhancers in granule cell precursors and gyrification of the cerebellum
CHARGE syndrome
Support
Clinical exome sequencing: results from 2819 samples reflecting 1000 families.
CHARGE syndrome
ASD, ID
Support
Autism-linked CHD gene expression patterns during development predict multi-organ disease phenotypes.
Support
Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations.
ASD
Support
NGS Custom Panel Implementation in Patients with Non-Syndromic Autism Spectrum Disorders in the Clinical Routine of a Tertiary Hospital
ASD
Support
An Intronic Variant of CHD7 Identified in Autism Patients Interferes with Neuronal Differentiation and Development
ASD
Support
The genomic landscape of balanced cytogenetic abnormalities associated with human congenital anomalies.
Multiple congenital anomalies
Support
Integrating de novo and inherited variants in 42
ASD
Support
Oligodendrocyte precursor survival and differentiation requires chromatin remodeling by Chd7 and Chd8.
Support
CHD8 interacts with CHD7, a protein which is mutated in CHARGE syndrome.
Support
ASD
DD, ID, epilepsy/seizures
Support
Should autism spectrum disorder be considered part of CHARGE syndrome? A cross-sectional study of 46 patients
CHARGE syndrome
Support
De novo genic mutations among a Chinese autism spectrum disorder cohort.
ASD
Support
Whole-exome sequencing identified five novel de novo variants in patients with unexplained intellectual disability
DD, ID
Support
Integrative Analyses of De Novo Mutations Provide Deeper Biological Insights into Autism Spectrum Disorder.
ASD
Support
Exome sequencing of 457 autism families recruited online provides evidence for autism risk genes
ASD
Support
Meta-analysis of 2,104 trios provides support for 10 new genes for intellectual disability
ID
Support
Next-generation phenotyping integrated in a national framework for patients with ultrarare disorders improves genetic diagnostics and yields new molecular findings
DD
Support
Clinical Targeted Panel Sequencing Analysis in Clinical Evaluation of Children with Autism Spectrum Disorder in China
ASD
Support
Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands.
Congenital heart disease (CHD)
Neurodevelopmental disorders (NDD)
Support
ASD
Support
Autism-associated missense genetic variants impact locomotion and neurodevelopment in Caenorhabditis elegans.
ASD
Support
Large-scale discovery of novel genetic causes of developmental disorders.
ID
Support
Kismet/CHD7/CHD8 affects gut microbiota, mechanics, and the gut-brain axis in Drosophila melanogaster
Support
Genetic and Phenotype Analysis of a Chinese Cohort of Infants and Children With Epilepsy
Epilepsy/seizures
Support
Genomic diagnosis for children with intellectual disability and/or developmental delay.
ID
Support
ADHD, DD, ID
Support
Comprehensive Analysis of Rare Variants of 101 Autism-Linked Genes in a Hungarian Cohort of Autism Spectrum Disorder Patients.
ASD
CHARGE syndrome
Support
Performance comparison of bench-top next generation sequencers using microdroplet PCR-based enrichment for targeted sequencing in patients with aut...
ASD
ID, epilepsy
Support
The CHD family chromatin remodeling enzyme, Kismet, promotes both clathrin-mediated and activity-dependent bulk endocytosis
Recent Recommendation
Low load for disruptive mutations in autism genes and their biased transmission.
ASD
Recent Recommendation
Craniosynostosis
Recent Recommendation
CHD7, the gene mutated in CHARGE syndrome, regulates genes involved in neural crest cell guidance.
Recent Recommendation
The CHD8/CHD7/Kismet family links blood-brain barrier glia and serotonin to ASD-associated sleep defects
Insomnia
Recent Recommendation
The chromatin remodeler CHD7 regulates adult neurogenesis via activation of SoxC transcription factors.
Recent Recommendation
Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme.
Recent Recommendation
Chromatin remodeling by the CHD7 protein is impaired by mutations that cause human developmental disorders.
Recent Recommendation
The chromatin remodeling factor CHD7 controls cerebellar development by regulating reelin expression.
Recent Recommendation
Chd7 cooperates with Sox10 and regulates the onset of CNS myelination and remyelination.
Recent Recommendation
De novo mutations in congenital heart disease with neurodevelopmental and other congenital anomalies.
Congenital heart disease (CHD)
DD, learning disabilities
Variant ID
Variant Type
Allele Change
Residue Change
Inheritance Pattern
Inheritance Association
Family Type
Author, Year
 GEN280R001 
 copy_number_loss 
  
  
 De novo 
  
  
 GEN280R002 
 translocation 
  
  
  
  
  
 GEN280R003 
 stop_gained 
 c.469C>T 
 p.Arg157Ter 
  
  
  
 GEN280R004 
 stop_gained 
 c.1078G>T 
 p.Gly360Ter 
  
  
  
 GEN280R005 
 stop_gained 
 c.1714C>T 
 p.Gln572Ter 
 De novo 
  
  
 GEN280R006 
 missense_variant 
 c.3082A>G 
 p.Ile1028Val 
 De novo 
  
  
 GEN280R007 
 missense_variant 
 c.3770T>G 
 p.Leu1257Arg 
 De novo 
  
  
 GEN280R008 
 stop_gained 
 c.5418C>G 
 p.Tyr1806Ter 
 De novo 
  
  
 GEN280R009 
 stop_gained 
 c.6051T>A 
 p.Cys2017Ter 
  
  
  
 GEN280R010 
 stop_gained 
 c.6070C>T 
 p.Arg2024Ter 
  
  
  
 GEN280R011 
 stop_gained 
 c.7824T>A 
 p.Tyr2608Ter 
 De novo 
  
  
 GEN280R012 
 splice_site_variant 
 G>A 
 p.? 
 De novo 
  
  
 GEN280R013 
 missense_variant 
 c.2986G>A 
 p.Gly996Ser 
 De novo 
  
 Simplex 
 GEN280R014 
 frameshift_variant 
 c.2245del 
 p.Leu749Ter 
 Familial 
 Maternal 
 Simplex 
 GEN280R015 
 frameshift_variant 
 c.8941_8942insA 
 p.Leu2981HisfsTer5 
 Familial 
 Paternal 
 Simplex 
 GEN280R016 
 missense_variant 
 c.3566G>A 
 p.Arg1189His 
 Familial 
 Paternal 
 Simplex 
 GEN280R017 
 missense_variant 
 c.7880G>A 
 p.Arg2627Gln 
 Unknown 
  
 Unknown 
 GEN280R018 
 missense_variant 
 c.7652C>A 
 p.Thr2551Asn 
 Unknown 
  
 Unknown 
 GEN280R019 
 copy_number_loss 
  
  
 De novo 
  
 Simplex 
 GEN280R020 
 missense_variant 
 c.2657G>A 
 p.Arg886Gln 
 De novo 
  
 Simplex 
 GEN280R021 
 stop_gained 
 c.1717-20232C>T 
  
 De novo 
  
  
 GEN280R022 
 stop_gained 
 c.5181C>G 
 p.Tyr1727Ter 
 De novo 
  
  
 GEN280R023 
 missense_variant 
 c.4516G>A 
 p.Gly1506Ser 
 Familial 
 Maternal 
  
 GEN280R024 
 missense_variant 
 c.4516G>A 
 p.Gly1506Ser 
 Familial 
 Paternal 
  
 GEN280R025 
 stop_gained 
 c.2959C>T 
 p.Arg987Ter 
 De novo 
  
  
 GEN280R026 
 translocation 
  
  
 De novo 
  
  
 GEN280R027 
 frameshift_variant 
 ACCAGTGTCTG>A 
  
 De novo 
  
 Simplex 
 GEN280R028 
 missense_variant 
 c.6955C>T 
 p.Arg2319Cys 
 De novo 
  
  
 GEN280R029 
 stop_gained 
 c.1717-5658C>T 
  
 De novo 
  
  
 GEN280R030 
 stop_gained 
 c.1717-11683C>T 
  
 De novo 
  
  
 GEN280R031 
 missense_variant 
 c.7880G>A 
 p.Arg2627Gln 
 De novo 
  
 Simplex 
 GEN280R032 
 missense_variant 
 c.7193G>A 
 p.Arg2398His 
 Familial 
 Paternal 
 Simplex 
 GEN280R033 
 missense_variant 
 c.7502C>A 
 p.Ser2501Tyr 
 Unknown 
 Not maternal 
 Simplex 
 GEN280R034 
 frameshift_variant 
 c.1717-20205del 
  
 De novo 
  
  
 GEN280R035 
 synonymous_variant 
 c.1263A>G 
 p.Pro421= 
 De novo 
  
  
 GEN280R036 
 intron_variant 
 c.4851-31C>T 
  
 Familial 
 Paternal 
 Simplex 
 GEN280R037 
 intron_variant 
 c.4851-31C>T 
  
 Familial 
 Paternal 
 Simplex 
 GEN280R038 
 intron_variant 
 c.4851-31C>T 
  
 Familial 
 Paternal 
 Simplex 
 GEN280R039 
 intron_variant 
 c.4851-31C>T 
  
 Familial 
 Paternal 
 Simplex 
 GEN280R040 
 intron_variant 
 c.1717-17396C>T 
  
 Familial 
 Paternal 
 Simplex 
 GEN280R041 
 intron_variant 
 c.4851-31C>T 
  
 Familial 
 Maternal 
 Simplex 
 GEN280R042 
 frameshift_variant 
 c.4493_4506del 
 p.Ile1498ArgfsTer9 
 Unknown 
  
  
 GEN280R043 
 stop_gained 
 c.2643T>A 
 p.Tyr881Ter 
 Unknown 
  
  
 GEN280R044 
 stop_gained 
 c.5181C>G 
 p.Tyr1727Ter 
 Unknown 
  
  
 GEN280R045 
 stop_gained 
 c.844C>T 
 p.Gln282Ter 
 De novo 
  
  
 GEN280R046 
 missense_variant 
 c.304C>T 
 p.His102Tyr 
 Familial 
 Paternal 
  
 GEN280R047 
 missense_variant 
 c.7013A>T 
 p.Gln2338Leu 
 De novo 
  
 Simplex 
 GEN280R048 
 stop_gained 
 c.7252C>T 
 p.Arg2418Ter 
 De novo 
  
  
 GEN280R049 
 synonymous_variant 
 c.1644G>A 
 p.Pro548%3D 
 De novo 
  
  
 GEN280R050 
 missense_variant 
 c.3640C>G 
 p.Gln1214Glu 
 De novo 
  
  
 GEN280R051 
 missense_variant 
 c.5050G>A 
 p.Gly1684Ser 
 De novo 
  
  
 GEN280R052 
 missense_variant 
 c.7708C>T 
 p.Pro2570Ser 
 De novo 
  
  
 GEN280R053 
 missense_variant 
 c.8326C>T 
 p.Pro2776Ser 
 De novo 
  
  
 GEN280R054 
 missense_variant 
 c.8692A>G 
 p.Met2898Val 
 De novo 
  
  
 GEN280R055 
 missense_variant 
 c.6307G>A 
 p.Gly2103Ser 
 De novo 
  
 Simplex 
 GEN280R056 
 missense_variant 
 c.2176G>T 
 p.Asp726Tyr 
 Familial 
  
 Multiplex 
 GEN280R057 
 frameshift_variant 
 c.2352dup 
 p.Asn785GlnfsTer12 
 Unknown 
 Not maternal 
  
 GEN280R058 
 missense_variant 
 c.2701G>A 
 p.Val901Met 
 Familial 
 Maternal 
  
 GEN280R059 
 missense_variant 
 c.5202C>A 
 p.His1734Gln 
 De novo 
  
  
 GEN280R060 
 missense_variant 
 c.6904G>A 
 p.Glu2302Lys 
 Unknown 
  
 Extended multiplex 
 GEN280R061 
 missense_variant 
 c.3973T>C 
 p.Tyr1325His 
 Unknown 
  
  
 GEN280R062 
 missense_variant 
 c.3973T>C 
 p.Tyr1325His 
 Unknown 
  
  
 GEN280R063 
 stop_gained 
 c.2839C>T 
 p.Arg947Ter 
 De novo 
  
  
 GEN280R064 
 stop_gained 
 c.1735C>T 
 p.Gln579Ter 
 De novo 
  
  
Chromosome
CNV Locus
CNV Type
# of studies
Animal Model
8
Duplication
 1
 
8
Duplication
 1
 
8
Deletion
 1
 
8
Duplication
 1
 
8
Deletion
 2
 

Model Summary

The deletion of Chd7 causes inner year problems in the mouse model and mutations in this gene have been found in some patients with the CHARGE syndrome.

References

Type
Title
Author, Year
Primary
Otitis media in a new mouse model for CHARGE syndrome with a deletion in the Chd7 gene.
Additional
The chromatin remodeling factor CHD7 controls cerebellar development by regulating reelin expression.
Additional
CHARGE syndrome protein CHD7 regulates epigenomic activation of enhancers in granule cell precursors and gyrification of the cerebellum
Model Type: Genetic
Model Genotype: Heterozygous
Mutation: Mice designated as OME ( otitis media and eye defects) mice, as hearing deficits were observed in these mice in the Jackson Laboratory- these mice harbor a spontaneous mutation, transmitted in an autosomal dominant manner, located somewhere in the Chd7 gene- the exact location is not known. Exon 1 and 4 are spliced together leading to the deletion of exon 2 and 3.
Allele Type: NA
Strain of Origin:
Genetic Background: BALB/cByJ
ES Cell Line:
Mutant ES Cell Line:
Model Source:
Category
Entity
Quantity
Experimental Paradigm
Age at Testing
Swimming ability1
Decreased
 NA
 Unreported
Head bobbing1
Increased
 General observations
 Unreported
Circling1
Increased
 General observations
 Unreported
Hearing1
Decreased
 Auditory brainstem response test
 3-17 weeks
Inner ear anatomy1
Increased
 Histology
 3-11 weeks
Skeletal development: craniofacial1
Increased
 Cranial measurements
 Unreported
Size/growth1
Decreased
 General observations
 3-4 weeks
General characteristics1
 No change
 General observations
 Unreported
 Not Reported: Circadian sleep/wake cycle, Communications, Emotion, Immune response, Learning & memory, Maternal behavior, Molecular profile, Neuroanatomy / ultrastructure / cytoarchitecture, Neurophysiology, Physiological parameters, Seizure, Social behavior


Interactor Symbol Interactor Name Interactor Organism Entrez ID Uniprot ID Interaction Type Evidence Reference
ABAT 4-aminobutyrate aminotransferase 268860 P61922 ChIP-Seq
Engelen E , et al. 2011
ABI2 abl-interactor 2 329165 P62484 ChIP-Seq
Engelen E , et al. 2011
ARID1A AT rich interactive domain 1A (SWI-like) 93760 A2BH40 IP; MS
Engelen E , et al. 2011
ARID2 AT rich interactive domain 2 (ARID, RFX-like) 196528 Q68CP9 IP/WB
Bajpai R , et al. 2010
BAF155 SWI/SNF complex subunit SMARCC1 6599 Q92922 MS/MS; IP/WB
Laurette P , et al. 2015
BAF170 SWI/SNF complex subunit SMARCC2 6601 Q8TAQ2 MS/MS; IP/WB
Laurette P , et al. 2015
BCAR3 breast cancer anti-estrogen resistance 3 29815 Q9QZK2 ChIP-Seq
Engelen E , et al. 2011
BRD7 bromodomain containing 7 29117 Q9NPI1 IP; MS; IP/WB
Bajpai R , et al. 2010
BRG1 Transcription activator BRG1 6597 P51532 MS/MS; IP/WB
Laurette P , et al. 2015
CCNC cyclin C 51813 Q62447 ChIP-Seq
Engelen E , et al. 2011
CDK8 cyclin-dependent kinase 8 264064 Q8R3L8 ChIP-Seq
Engelen E , et al. 2011
CHD8 chromodomain helicase DNA binding protein 8 57680 Q9HCK8 Y2H; Bimolecular fluorescence complementation assay; IP/WB
Batsukh T , et al. 2010
CMTM3 CKLF-like MARVEL transmembrane domain containing 3 68119 Q99LJ5 ChIP-Seq
Engelen E , et al. 2011
CORO1C coronin, actin binding protein 1C 23790 Q9WUM4 ChIP-Seq
Engelen E , et al. 2011
CPD carboxypeptidase D 12874 O89001 ChIP-Seq
Engelen E , et al. 2011
Creb3l2 cAMP responsive element binding protein 3-like 2 362339 Q6QDP7 ChIP-Seq; qRT-PCR
He D , et al. 2016
CSRP1 cysteine and glycine-rich protein 1 1465 P97315 ChIP-Seq
Engelen E , et al. 2011
CTCF CCCTC-binding factor (zinc finger protein) 10664 B5MC38 GST
Allen MD , et al. 2007
DYNC1LI2 dynein, cytoplasmic 1 light intermediate chain 2 234663 Q6PDL0 ChIP-Seq
Engelen E , et al. 2011
E2F1 E2F transcription factor 1 13555 Q61501 ChIP
Schnetz MP , et al. 2010
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 66143 Q9D1M4 ChIP-Seq
Engelen E , et al. 2011
EGFR epidermal growth factor receptor 13649 Q01279 ChIP-Seq
Engelen E , et al. 2011
EIF1AY eukaryotic translation initiation factor 1A, X-linked 66235 Q8BMJ3 ChIP-Seq
Engelen E , et al. 2011
EP300 E1A binding protein p300 328572 B2RWS6 ChIP; IP/WB
Schnetz MP , et al. 2010
EZH2 enhancer of zeste homolog 2 (Drosophila) 14056 Q61188 ChIP
Schnetz MP , et al. 2010
FAM124B Protein FAM124B 79843 Q9H5Z6 Y2H; IP/WB; MS
Batsukh T , et al. 2013
FAM190B granule cell antiserum positive 14 72972 Q3UHI0 ChIP-Seq
Engelen E , et al. 2011
FGD4 FYVE, RhoGEF and PH domain containing 4 224014 Q91ZT5 ChIP-Seq
Engelen E , et al. 2011
FMR1 fragile X mental retardation 1 2332 G8JLE9 PAR-CLIP; RNA immunoprecipitation (RIP)
Ascano M Jr , et al. 2012
FRMD4B FERM domain containing 4B 232288 Q920B0 ChIP-Seq
Engelen E , et al. 2011
GATAD2A GATA zinc finger domain containing 2A 234366 Q8CHY6 IP; MS
Engelen E , et al. 2011
Gbx2 Homeobox protein GBX-2 14472 P48031 ChIP-qPCR
Yu T , et al. 2013
GLI2 GLI-Kruppel family member GLI2 14633 Q0VGT2 ChIP-Seq
Engelen E , et al. 2011
GLI3 GLI-Kruppel family member GLI3 14634 Q61602 ChIP-Seq
Engelen E , et al. 2011
GRIA2 glutamate receptor, ionotropic, AMPA2 (alpha 2) 14800 P23819 ChIP-Seq
Engelen E , et al. 2011
HES5 hairy and enhancer of split 5 (Drosophila) 15208 P70120 ChIP-Seq
Engelen E , et al. 2011
ITGA6 integrin alpha 6 16403 Q61739 ChIP-Seq
Engelen E , et al. 2011
JAG1 jagged 1 16449 Q9QXX0 ChIP-Seq
Engelen E , et al. 2011
KCTD17 potassium channel tetramerisation domain containing 17 72844 E0CYQ0 ChIP-Seq
Engelen E , et al. 2011
KLF15 Kruppel-like factor 15 66277 Q9EPW2 ChIP-Seq
Engelen E , et al. 2011
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) 78651 P62313 ChIP-Seq
Engelen E , et al. 2011
MAPT microtubule-associated protein tau 17762 P10637 ChIP-Seq
Engelen E , et al. 2011
Mbp myelin basic protein 24547 P02688 ChIP-Seq; qRT-PCR
He D , et al. 2016
MITF microphthalmia-associated transcription factor 4286 O75030 MS/MS; IP/WB
Laurette P , et al. 2015
MOB3B MOB kinase activator 3B 214944 Q8VE04 ChIP-Seq
Engelen E , et al. 2011
MTA1 metastasis associated 1 116870 Q8K4B0 IP; MS
Engelen E , et al. 2011
MTA2 metastasis-associated gene family, member 2 23942 Q9R190 IP; MS
Engelen E , et al. 2011
MYC myelocytomatosis oncogene 17869 P01108 ChIP
Schnetz MP , et al. 2010
MYCN v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 18109 P03966 ChIP
Schnetz MP , et al. 2010
Myrf myelin regulatory factor 293736 D4A352 ChIP-Seq; qRT-PCR
He D , et al. 2016
NANOG Nanog homeobox 71950 Q80Z64 ChIP
Schnetz MP , et al. 2010
NLK nemo-like kinase 51701 Q9UBE8 GST
Takada I , et al. 2007
NRAS neuroblastoma ras oncogene 18176 P08556 ChIP-Seq
Engelen E , et al. 2011
OLIG1 oligodendrocyte transcription factor 1 116448 Q9JKN5 IP; MS
Engelen E , et al. 2011
Olig2 oligodendrocyte lineage transcription factor 2 304103 G3V612 ChIP-Seq
He D , et al. 2016
Otx2 Homeobox protein OTX2 P80206 ChIP-qPCR
Yu T , et al. 2013
OXCT1 3-oxoacid CoA transferase 1 67041 Q9D0K2 ChIP-Seq
Engelen E , et al. 2011
p53 Cellular tumor antigen p53 22059 P02340 ChIP; qRT-PCR
Van Nostrand JL , et al. 2014
PARP1 poly (ADP-ribose) polymerase 1 142 P09874 IP; MS
Bajpai R , et al. 2010
PBRM1 polybromo 1 55193 Q86U86 IP; MS; IP/WB
Bajpai R , et al. 2010
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 170768 A7UAK4 ChIP-Seq
Engelen E , et al. 2011
POU5F1 POU domain, class 5, transcription factor 1 18999 P20263 ChIP; ChIP-Seq; ChIP-chip
Schnetz MP , et al. 2010
PPARG peroxisome proliferator-activated receptor gamma 5468 P37231 GST
Takada I , et al. 2007
RAB33B RAB33B, member of RAS oncogene family 19338 O35963 ChIP-Seq
Engelen E , et al. 2011
RBPJ recombination signal binding protein for immunoglobulin kappa J region 19664 P31266 ChIP-Seq
Engelen E , et al. 2011
RGS8 regulator of G-protein signaling 8 67792 Q8BXT1 ChIP-Seq
Engelen E , et al. 2011
RNF2 ring finger protein 2 19821 Q9CQJ4 ChIP
Schnetz MP , et al. 2010
SALL3 sal-like 3 (Drosophila) 20689 Q62255 IP; MS
Engelen E , et al. 2011
SEC63 SEC63-like (S. cerevisiae) 140740 Q8VHE0 ChIP-Seq
Engelen E , et al. 2011
SETDB1 SET domain, bifurcated 1 9869 Q15047 GST
Takada I , et al. 2007
SLC25A36 solute carrier family 25, member 36 192287 Q922G0 ChIP-Seq
Engelen E , et al. 2011
SMAD1 MAD homolog 1 (Drosophila) 17125 P70340 ChIP
Schnetz MP , et al. 2010
SMAD5 SMAD family member 5 17129 P97454 Y2H; GST
Liu Y , et al. 2013
SMAD8 Mothers against decapentaplegic homolog 9 55994 Q9JIW5 Y2H; GST
Liu Y , et al. 2013
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 6597 A7E2E1 IP; MS; IP/WB
Bajpai R , et al. 2010
Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 171379 Q8K1P7 ChIP-Seq; Expression microarray
He D , et al. 2016
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 6598 Q12824 IP; MS
Bajpai R , et al. 2010
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 6599 Q58EY4 IP; MS; IP/WB
Bajpai R , et al. 2010
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 6601 Q8TAQ2 IP; MS; IP/WB
Bajpai R , et al. 2010
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 6602 Q96GM5 IP; MS
Bajpai R , et al. 2010
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 6603 Q92925 IP; MS
Bajpai R , et al. 2010
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 6604 Q6P9Z1 IP; MS
Bajpai R , et al. 2010
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 6605 Q969G3 IP; MS; IP/WB
Bajpai R , et al. 2010
Sox10 SRY-box containing gene 10 20665 Q04888 IP/WB; Co-localization
ChIP-Seq
He D , et al. 2016
Sox10 SRY box 10 29361 O55170 IP/WB; Co-localization
ChIP-Seq
He D , et al. 2016
SOX11 SRY-box containing gene 11 20666 Q7M6Y2 ChIP-Seq
Engelen E , et al. 2011
SOX2 SRY-box containing gene 2 20674 P48432 Affinity chromatography; MS; IP/WB; GST; IP
Engelen E , et al. 2011
Sox3 P53784 ChIP-Seq; ChIP-chip
Sharov AA , et al. 2014
SOX9 SRY (sex determining region Y)-box 9 6662 P48436 ChIP-qPCR
Bajpai R , et al. 2010
Sp7 Sp7 transcription factor 300260 Q6IMK2 ChIP-Seq; qRT-PCR
He D , et al. 2016
SPEG SPEG complex locus 11790 Q62407 ChIP-Seq
Engelen E , et al. 2011
SRC Rous sarcoma oncogene 20779 P05480 ChIP-Seq
Engelen E , et al. 2011
STAT3 signal transducer and activator of transcription 3 20848 P42227 ChIP
Schnetz MP , et al. 2010
SUZ12 suppressor of zeste 12 homolog (Drosophila) 52615 Q80U70 ChIP
Schnetz MP , et al. 2010
SYNE2 synaptic nuclear envelope 2 319565 Q6ZWQ0 ChIP-Seq
Engelen E , et al. 2011
TADA1 transcriptional adaptor 1 27878 Q99LM9 ChIP-Seq
Engelen E , et al. 2011
Tcf3 transcription factor 3 21423 P15806 ChIP-Seq; ChIP-chip
Sharov AA , et al. 2014
TERF2 telomeric repeat binding factor 2 7014 Q9NYB0 Affinity chromatography; MS
Giannone RJ , et al. 2010
TGFBR2 transforming growth factor, beta receptor II 21813 Q62312 ChIP-Seq
Engelen E , et al. 2011
TMEM132C transmembrane protein 132C 208213 Q8CEF9 ChIP-Seq
Engelen E , et al. 2011
TOP3B topoisomerase (DNA) III beta 8940 O95985 HITS-CLIP
Xu D , et al. 2013
TPM1 tropomyosin 1, alpha 22003 P58771 ChIP-Seq
Engelen E , et al. 2011
TULP3 tubby-like protein 3 22158 O88413 ChIP-Seq
Engelen E , et al. 2011
TWIST1 twist homolog 1 (Drosophila) 7291 Q15672 ChIP-qPCR
Bajpai R , et al. 2010
Ugt8 UDP glycosyltransferase 8 50555 Q09426 ChIP-Seq
He D , et al. 2016
VARS valyl-tRNA synthetase 22321 Q9Z1Q9 IP; MS
Engelen E , et al. 2011
ZBTB20 zinc finger and BTB domain containing 20 26137 Q9HC78 ChIP; MS
IP; MS
Engelen E , et al. 2011
ZBTB20 zinc finger and BTB domain containing 20 56490 Q8K0L9 ChIP; MS
IP; MS
Engelen E , et al. 2011
ZFX zinc finger protein X-linked 22764 P17012 ChIP
Schnetz MP , et al. 2010
ZHX3 zinc fingers and homeoboxes 3 320799 Q8C0Q2 ChIP-Seq
Engelen E , et al. 2011

CMTM3
HELP
Copyright © 2017 MindSpec, Inc.