AutDB - Autism Database

Gene
CNV
Animal Model
PIN

APC

Homo sapiens

Gene Name: adenomatosis polyposis coli
Aliases: GS, DP2, DP3, FAP, FPC, DP2.5
Chromosome No: 5
Chromosome Band: 5q22.2
Genetic Category: Genetic Association-Functional-Rare single gene variant

Summary Statistics:

ASD Reports: 13
Recent Reports: 6
Annotated variants: 7
Associated CNVs: 7
Evidence score: 2

Associated Disorders:

Summary
Sequence Variants

Relevance to Autism

Rare mutation (Barber et al., 1994) and genetic association (Zhou et al., 2007) of the APC gene has been identified with autism.

Molecular Function

The encoded protein is a tumor suppressor.

External Links

References

Type

Title

Type of Disorder

Associated Disorders

Author, Year

Primary

Adenomatous polyposis coli and a cytogenetic deletion of chromosome 5 resulting from a maternal intrachromosomal insertion.

ASD

adenomatous polyposis coli

Barber JC , et al. 1994

Positive Association

Association of adenomatous polyposis coli (APC) gene polymorphisms with autism spectrum disorder (ASD).

ASD

Zhou XL , et al. 2007

Support

Integrating de novo and inherited variants in 42

ASD

Zhou X et al. 2022

Support

ASD

ADHD, OCD, learning disability

et al.

Support

ASD

Wang J et al. 2023

Support

Ryner RF et al. 2023

Highly Cited

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC.

Morin PJ , et al. 1997

Recent Recommendation

A two-step model for colon adenoma initiation and progression caused by APC loss.

Phelps RA , et al. 2009

Recent Recommendation

Alterations of the Wnt signaling pathway during the neoplastic progression of Barrett's esophagus.

Clment G , et al. 2006

Recent Recommendation

APC is an RNA-binding protein, and its interactome provides a link to neural development and microtubule assembly.

Preitner N , et al. 2014

Recent Recommendation

Adenomatous polyposis coli protein deletion leads to cognitive and autism-like disabilities.

Mohn JL , et al. 2014

Recent Recommendation

The postsynaptic adenomatous polyposis coli (APC) multiprotein complex is required for localizing neuroligin and neurexin to neuronal nicotinic syn...

Rosenberg MM , et al. 2010

Recent Recommendation

Adenomatous polyposis coli and Asef function downstream of hepatocyte growth factor and phosphatidylinositol 3-kinase.

Kawasaki Y , et al. 2009

Rare

Variant ID

Variant Type

Allele Change

Residue Change

Inheritance Pattern

Inheritance Association

Family Type

Author, Year

GEN013R001

copy_number_loss

De novo

Simplex

Barber JC , et al. 1994

GEN013R002

missense_variant

c.5296G>A

p.Asp1766Asn

De novo

Zhou X et al. 2022

GEN013R003

missense_variant

c.992C>T

p.Ser331Leu

De novo

Zhou X et al. 2022

GEN013R004

frameshift_variant

c.5253_5256del

p.Lys1752GlyfsTer9

De novo

Simplex

Wang J et al. 2023

GEN013R005

missense_variant

c.3920T>A

p.Ile1307Lys

Familial

Maternal

Simplex

et al.

GEN013R006

missense_variant

c.3920T>A

p.Ile1307Lys

Familial

Paternal

Multiplex

et al.

Common

Variant ID

Polymorphism

SNP ID

Allele Change

Residue Change

Population Origin

Population Stage

Author, Year

GEN013C001

3_prime_UTR_variant

rs1804197

c.*86C>A

Swedish

Discovery

Zhou XL , et al. 2007

Chromosome

CNV Locus

CNV Type

# of studies

Animal Model

5q12.1-q35.3

Duplication

5q15-q22.3

Duplication

5q21.1-q22.2

Deletion

5q21.1-q23.3

Deletion

5q21.3-q22.2

Deletion

5q21.3-q33.2

Deletion

5q22.2

Deletion-Duplication

Apc

Mus musculus

Gene Name: adenomatous polyposis coli
Aliases: CC1, Min, mAPC, AI047805, AU020952, AW124434
Human Ortholog: APC

Summary Statistics:

# of Reports: 1
# of Models: 2

Model Summary

The conditional knock out of the Apc gene from the forebrain excitatory neurons causes several beavioral and learning abnormalities, like deficits in spatial learning and memory; increased repetitive behavior and decreased sociability.

References

Type

Title

Author, Year

Primary

Adenomatous polyposis coli protein deletion leads to cognitive and autism-like disabilities.

Mohn JL , et al. 2014

M_APC_1_CKO_HM

Model Type: Genetic
Model Genotype: Homozygous
Mutation: Conditional deletion of exons 11 and 12 of the Apc (resulting in a truncated protein of 468 aas) using CamkII- cre in excitatory neurons of the forebrain. A reporter line was also developed crossing Thy1-YFP to the Apc CKO
Allele Type: Conditional loss-of-function
Strain of Origin: 129S6/SvEvTac
Genetic Background: 129S6/SvEvTac * C57BL/6
ES Cell Line: TC1/TC-1
Mutant ES Cell Line:
Model Source: JAX

M_APC_2_CKO_HM_THY1-YFP

Model Type: Genetic
Model Genotype: Homozygous
Mutation: The Apc null mice, lacking the functional protein from forebrain excitatory neurons, were crossed with Thy1- YFP mice to visualize neuronal spines.
Allele Type: Targeted (marker)
Strain of Origin: 129S6/SvEvTac
Genetic Background: 129S6/SvEvTac * C57BL/6
ES Cell Line:
Mutant ES Cell Line:
Model Source:

M_APC_1_CKO_HM

M_APC_2_CKO_HM_THY1-YFP

Category

Entity

Quantity

Experimental Paradigm

Age at Testing

Neuroanatomy / Ultrastructure / Cytoarchitecture

Dendritic architecture: spine density¹

Increased

Description: Apc null mice (with thy1-yfp) have increased spine density in the pyramidal neuronals of cortical layer v and hippocampal ca1 pyramidal neurons
Exp Paradigm: NA

Golgi-cox staining

Unreported

References: 1: Mohn JL , et al. 2014

Not Reported: Circadian sleep/wake cycle, Communications, Developmental profile, Emotion, Immune response, Learning & memory, Maternal behavior, Molecular profile, Motor phenotype, Neurophysiology, Physiological parameters, Repetitive behavior, Seizure, Sensory, Social behavior

APC

Homo sapiens

Gene Name: adenomatous polyposis coli
Gene Aliases: BTPS2, DP2, DP2.5, DP3, GS

Summary Statistics:

Total Interactions: 391
Total Publications: 36

Interactome
Interaction Table

Download APC's Cytoscape file

Interactor Symbol	Interactor Name	Entrez ID	Uniprot ID	Evidence	Reference
11-Sep	septin 11	52398	Q8C1B7	HITS-CLIP	Preitner N , et al. 2014
4932438A13Rik	RIKEN cDNA 4932438A13 gene	229227	A2AAE1	HITS-CLIP	Preitner N , et al. 2014
6-Mar	membrane-associated ring finger (C3HC4) 6	223455	Q6ZQ89	HITS-CLIP	Preitner N , et al. 2014
Abhd17c	abhydrolase domain containing 17C	70178	Q8VCV1	HITS-CLIP	Preitner N , et al. 2014
Abi2	abl-interactor 2	329165	P62484	HITS-CLIP	Preitner N , et al. 2014
ACADVL	acyl-CoA dehydrogenase, very long chain	37	P49748	IP; LC-MS/MS	Huttlin EL , et al. 2015
Acly	ATP citrate lyase	104112	Q91V92	HITS-CLIP	Preitner N , et al. 2014
Actb	actin, beta	11461	P60710	HITS-CLIP	Preitner N , et al. 2014
ACTN1	actinin, alpha 1	87	P12814	Y2H	Bandyopadhyay S , et al. 2010
Actr1a	ARP1 actin-related protein 1A, centractin alpha	54130	P61164	HITS-CLIP	Preitner N , et al. 2014
Actr1b	ARP1 actin-related protein 1B, centractin beta	226977	Q8R5C5	HITS-CLIP	Preitner N , et al. 2014
Aff4	AF4/FMR2 family, member 4	93736	Q9ESC8	HITS-CLIP	Preitner N , et al. 2014
AGFG1	ArfGAP with FG repeats 1	3267	P52594	Y2H	Bandyopadhyay S , et al. 2010
Akap11	A kinase (PRKA) anchor protein 11	219181	E9Q777	HITS-CLIP	Preitner N , et al. 2014
Amfr	autocrine motility factor receptor	23802	Q9R049	HITS-CLIP	Preitner N , et al. 2014
Ank3	ankyrin 3, epithelial	11735	Q4U260	HITS-CLIP	Preitner N , et al. 2014
Ankrd12			Q6P211	HITS-CLIP	Preitner N , et al. 2014
ANKRD17	ankyrin repeat domain 17	26057	O75179	Y2H	Bandyopadhyay S , et al. 2010
Anp32a	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	11737	O35381	HITS-CLIP	Preitner N , et al. 2014
Anp32e	acidic (leucine-rich) nuclear phosphoprotein 32 family, member E	66471	P97822	HITS-CLIP	Preitner N , et al. 2014
ANXA7	annexin A7	310	P20073	Y2H	Bandyopadhyay S , et al. 2010
AP2B1	adaptor-related protein complex 2, beta 1 subunit	163	P63010	Y2H	Bandyopadhyay S , et al. 2010
AP2M1	adaptor-related protein complex 2, mu 1 subunit	1173	Q96CW1	IP; LC-MS/MS	Huttlin EL , et al. 2015
APC	adenomatous polyposis coli	324	P25054	IP/WB; in vitro binding assay	Su LK , et al. 1993
Araf	v-raf murine sarcoma 3611 viral oncogene homolog	11836	P04627	HITS-CLIP	Preitner N , et al. 2014
Arhgap11a	Rho GTPase activating protein 11A	228482	Q80Y19	HITS-CLIP	Preitner N , et al. 2014
ARHGEF4	Rho guanine nucleotide exchange factor (GEF) 4	50649	Q9NR80	Y2H; GST; IP/WB	Kawasaki Y , et al. 2000
Asap2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	211914	Q7SIG6	HITS-CLIP	Preitner N , et al. 2014
Atad1	ATPase family, AAA domain containing 1	67979	Q9D5T0	HITS-CLIP	Preitner N , et al. 2014
Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	11938	O55143	HITS-CLIP	Preitner N , et al. 2014
Atp5g3	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)	228033	P56384	HITS-CLIP	Preitner N , et al. 2014
Atp6ap2	ATPase, H+ transporting, lysosomal accessory protein 2	70495	Q9CYN9	HITS-CLIP	Preitner N , et al. 2014
Atxn7l3b	ataxin 7-like 3B	382423	Q3UD01	HITS-CLIP	Preitner N , et al. 2014
AXIN1	axin 1	8312	O15169	in vitro binding assay; IP/WB	Nakamura T , et al. 1998
AXIN2	axin 2	8313	Q9Y2T1	IP/WB	von Kries JP , et al. 2000
Azin1	antizyme inhibitor 1	54375	O35484	HITS-CLIP	Preitner N , et al. 2014
Basp1	brain abundant, membrane attached signal protein 1	70350	Q91XV3	HITS-CLIP	Preitner N , et al. 2014
Brwd1	bromodomain and WD repeat domain containing 1	93871	Q921C3	HITS-CLIP	Preitner N , et al. 2014
BTRC	beta-transducin repeat containing E3 ubiquitin protein ligase	8945	B2R8L3	IP; LC-MS/MS	Huttlin EL , et al. 2015
BUB1	budding uninhibited by benzimidazoles 1 homolog (yeast)	699	O43683	IP/WB; in vitro kinase assay	Kaplan KB , et al. 2001
BUB1B	budding uninhibited by benzimidazoles 1 homolog beta (yeast)	701	O60566	in vitro kinase assay	Kaplan KB , et al. 2001
BUB3	budding uninhibited by benzimidazoles 3 homolog (yeast)	9184	O43684	IP/WB; in vitro kinase assay	Kaplan KB , et al. 2001
C4A	complement component 4A (Rodgers blood group)	720	P0C0L4	Y2H	Bandyopadhyay S , et al. 2010
Cadm1	cell adhesion molecule 1	54725	Q8R5M8	HITS-CLIP	Preitner N , et al. 2014
Cadm4	cell adhesion molecule 4	260299	Q8R464	HITS-CLIP	Preitner N , et al. 2014
Calm1	calmodulin 1	12313	P62204	HITS-CLIP	Preitner N , et al. 2014
Calr	calreticulin	12317	P14211	HITS-CLIP	Preitner N , et al. 2014
Canx	calnexin	12330	P35564	HITS-CLIP	Preitner N , et al. 2014
Cbx5	chromobox homolog 5	23468	P45973	HITS-CLIP	Preitner N , et al. 2014
CCDC6	coiled-coil domain containing 6	8030	Q05CP8	IP; LC-MS/MS	Huttlin EL , et al. 2015
Ccnd2	cyclin D2	12444	P30280	HITS-CLIP	Preitner N , et al. 2014
Ccnj	cyclin J	240665	Q3TZI6	HITS-CLIP	Preitner N , et al. 2014
Cd24a	CD24a antigen	12484	P24807	HITS-CLIP	Preitner N , et al. 2014
Cdc42	cell division cycle 42	12540	P60766	HITS-CLIP	Preitner N , et al. 2014
Cdk5r1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	12569	P61809	HITS-CLIP	Preitner N , et al. 2014
Cdkn1b	cyclin-dependent kinase inhibitor 1B	12576	P46414	HITS-CLIP	Preitner N , et al. 2014
Celf3	CUGBP, Elav-like family member 3	78784	Q8CIN6	HITS-CLIP	Preitner N , et al. 2014
Celf4	CUGBP, Elav-like family member 4	108013	Q7TSY6	HITS-CLIP	Preitner N , et al. 2014
CGNL1	cingulin-like 1	84952	Q0VF96	Y2H	Bandyopadhyay S , et al. 2010
Chl1	"Processed neural cell adhesion molecule L1-like protein"	12661	P70232	HITS-CLIP	Preitner N , et al. 2014
Chtop	chromatin target of PRMT1	66511	Q9CY57	HITS-CLIP	Preitner N , et al. 2014
Cirbp	cold inducible RNA binding protein	12696	P60824	HITS-CLIP	Preitner N , et al. 2014
Cltc	clathrin, heavy polypeptide (Hc)	67300	Q68FD5	HITS-CLIP	Preitner N , et al. 2014
Cnr1	cannabinoid receptor 1 (brain)	12801	P47746	HITS-CLIP	Preitner N , et al. 2014
COG4	component of oligomeric golgi complex 4	25839	Q9H9E3	Y2H	Bandyopadhyay S , et al. 2010
COG5	component of oligomeric golgi complex 5	10466	Q9UP83	Y2H	Bandyopadhyay S , et al. 2010
Cpe	carboxypeptidase E	12876	Q00493	HITS-CLIP	Preitner N , et al. 2014
CREBBP	CREB binding protein	1387	Q92793	Y2H	Bandyopadhyay S , et al. 2010
Crebzf	CREB/ATF bZIP transcription factor	233490	Q91ZR3	HITS-CLIP	Preitner N , et al. 2014
Csde1	cold shock domain containing E1, RNA binding	229663	Q91W50	HITS-CLIP	Preitner N , et al. 2014
CSNK1A1	casein kinase 1, alpha 1	1452	P48729	Metabolic labeling with 32P	Godin KS , et al. 2009
Csnk1a1	casein kinase 1, alpha 1	93687	Q8BK63	HITS-CLIP	Preitner N , et al. 2014
CSNK1E	casein kinase 1, epsilon	1454	P49674	IP/WB	Rubinfeld B , et al. 2001
Csnk1e	casein kinase 1, epsilon	27373	Q9JMK2	HITS-CLIP	Preitner N , et al. 2014
CSNK2A1	casein kinase 2, alpha 1 polypeptide	1457	P68400	IP/WB; GST; in vitro kinase assay	Homma MK , et al. 2002
CSNK2B	casein kinase 2, beta polypeptide	1460	P67870	IP/WB; GST; in vitro kinase assay	Homma MK , et al. 2002
Cstf3	cleavage stimulation factor, 3' pre-RNA, subunit 3	228410	Q99LI7	HITS-CLIP	Preitner N , et al. 2014
CTBP1	C-terminal binding protein 1	1487	Q13363	GST; MS; IP/WB	Hamada F and Bienz M 2004
CTBP1	C-terminal binding protein 1	1487	Q13363	IP; LC-MS/MS	Huttlin EL , et al. 2015
Ctdspl2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2	329506	Q8BG15	HITS-CLIP	Preitner N , et al. 2014
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	1495	P35221	IP/WB; in vitro binding assay; Peptide mapping	Su LK , et al. 1993
CTNNA3	catenin (cadherin-associated protein), alpha 3	29119	A8K141	IP; LC-MS/MS	Huttlin EL , et al. 2015
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	1499	Q9WU82	X-ray crystallography; GST; IP/WB; High-throughput fluorescence polarization interaction analysis assay	Xing Y , et al. 2004
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	1499	Q9WU82	IP/WB	Cai J , et al. 2015
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	1499	Q9WU82	IP/WB; in vitro binding assay; Peptide mapping	Su LK , et al. 1993
Ctnnb1	catenin (cadherin associated protein), beta 1	12387	Q02248	HITS-CLIP	Preitner N , et al. 2014
CTNNBIP1	Beta-catenin-interacting protein 1	56998	Q9NSA3	IP; LC-MS/MS	Huttlin EL , et al. 2015
Cxadr	coxsackie virus and adenovirus receptor	13052	P97792	HITS-CLIP	Preitner N , et al. 2014
Cxcr4	chemokine (C-X-C motif) receptor 4	12767	P70658	HITS-CLIP	Preitner N , et al. 2014
Cyp51	cytochrome P450, family 51	13121	Q8K0C4	HITS-CLIP	Preitner N , et al. 2014
CYTH2	cytohesin 2	9266	Q99418	Y2H	Bandyopadhyay S , et al. 2010
Dcx	doublecortin	13193	O88809	HITS-CLIP	Preitner N , et al. 2014
Ddx17	DEAD (Asp-Glu-Ala-Asp) box polypeptide 17	67040	Q501J6	HITS-CLIP	Preitner N , et al. 2014
Ddx6	DEAD (Asp-Glu-Ala-Asp) box polypeptide 6	13209	P54823	HITS-CLIP	Preitner N , et al. 2014
Dhx9	DEAH (Asp-Glu-Ala-His) box polypeptide 9	13211	O70133	HITS-CLIP	Preitner N , et al. 2014
DLG3	discs, large homolog 3 (Drosophila)	1741	Q92796	Y2H; GST	Makino K , et al. 1997
Dpysl2	dihydropyrimidinase-like 2	12934	O08553	HITS-CLIP	Preitner N , et al. 2014
DST	dystonin	667	Q03001	Y2H	Bandyopadhyay S , et al. 2010
Dst	dystonin	13518	Q91ZU6	HITS-CLIP	Preitner N , et al. 2014
Dtx3	deltex 3 homolog (Drosophila)	80904	Q80V91	HITS-CLIP	Preitner N , et al. 2014
Dync1li2	dynein, cytoplasmic 1 light intermediate chain 2	234663	Q6PDL0	HITS-CLIP	Preitner N , et al. 2014
Dynll2	dynein light chain LC8-type 2	68097	Q9D0M5	HITS-CLIP	Preitner N , et al. 2014
Eif4h	eukaryotic translation initiation factor 4H	22384	Q9WUK2	HITS-CLIP	Preitner N , et al. 2014
Elavl2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)	15569	Q60899	HITS-CLIP	Preitner N , et al. 2014
Elavl3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)	15571	Q60900	HITS-CLIP	Preitner N , et al. 2014
Elavl4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)	15572	Q61701	HITS-CLIP	Preitner N , et al. 2014
Enc1	ectodermal-neural cortex 1	13803	O35709	HITS-CLIP	Preitner N , et al. 2014
EPAS1	endothelial PAS domain protein 1	2034	Q99814	Y2H	Bandyopadhyay S , et al. 2010
Epha4	Eph receptor A4	13838	Q03137	HITS-CLIP	Preitner N , et al. 2014
ERBB2IP	erbb2 interacting protein	55914	Q96RT1	Y2H	Bandyopadhyay S , et al. 2010
EXPH5	exophilin 5	23086	Q8NEV8	Y2H	Bandyopadhyay S , et al. 2010
Fabp7	fatty acid binding protein 7, brain	12140	P51880	HITS-CLIP	Preitner N , et al. 2014
Fam168b	family with sequence similarity 168, member B	214469	G3UWF0	HITS-CLIP	Preitner N , et al. 2014
Fam171a2	family with sequence similarity 171, member A2	217219	A2A699	HITS-CLIP	Preitner N , et al. 2014
FBXO30	F-box protein 30	84085	Q8TB52	Y2H	Bandyopadhyay S , et al. 2010
FBXW11	F-box and WD repeat domain containing 11	23291	Q9UKB1	IP; LC-MS/MS	Huttlin EL , et al. 2015
FHOD1	formin homology 2 domain containing 1	29109	Q9Y613	Y2H	Bandyopadhyay S , et al. 2010
Fjx1	four jointed box 1 (Drosophila)	14221	Q8BQB4	HITS-CLIP	Preitner N , et al. 2014
FLNA	filamin A, alpha	2316	P21333	Y2H	Bandyopadhyay S , et al. 2010
Flna	filamin, alpha	192176	Q8BTM8	HITS-CLIP	Preitner N , et al. 2014
Fnbp1l	formin binding protein 1-like	214459	Q8K012	HITS-CLIP	Preitner N , et al. 2014
Foxg1	forkhead box G1	15228	Q60987	HITS-CLIP	Preitner N , et al. 2014
Fubp1	far upstream element (FUSE) binding protein 1	51886	Q91WJ8	HITS-CLIP	Preitner N , et al. 2014
Fzd3	frizzled homolog 3 (Drosophila)	14365	Q61086	HITS-CLIP	Preitner N , et al. 2014
G2e3	G2/M-phase specific E3 ubiquitin ligase	217558	Q5RJY2	HITS-CLIP	Preitner N , et al. 2014
Gdi1	Rho GDP dissociation inhibitor (GDI) alpha	192662	Q99PT1	HITS-CLIP	Preitner N , et al. 2014
GIGYF2	GRB10 interacting GYF protein 2	26058	Q6Y7W6	Y2H	Bandyopadhyay S , et al. 2010
Gnb1	guanine nucleotide binding protein (G protein), beta 1	14688	P62874	HITS-CLIP	Preitner N , et al. 2014
GOLGA2	golgin A2	2801	Q08379	Y2H	Bandyopadhyay S , et al. 2010
Gpc2	"Secreted glypican-2"	71951	Q8BKV1	HITS-CLIP; EMSA	Preitner N , et al. 2014
Gpm6a	glycoprotein m6a	234267	P35802	HITS-CLIP	Preitner N , et al. 2014
Gpm6b	glycoprotein m6b	14758	P35803	HITS-CLIP	Preitner N , et al. 2014
Grb10	growth factor receptor bound protein 10	14783	Q60760	HITS-CLIP	Preitner N , et al. 2014
GSK3B	glycogen synthase kinase 3 beta	2932	P49841	IP/WB	Davies G , et al. 2001
Gsk3b	glycogen synthase kinase 3 beta	56637	Q9WV60	HITS-CLIP	Preitner N , et al. 2014
H1f0	"Histone H1.0, N-terminally processed"	14958	P10922	HITS-CLIP	Preitner N , et al. 2014
H3f3b	H3 histone, family 3B	15081	P84244	HITS-CLIP	Preitner N , et al. 2014
Hba-a1			P01942	HITS-CLIP	Preitner N , et al. 2014
Hba-a2	hemoglobin alpha, adult chain 1	15122	Q91VB8	HITS-CLIP	Preitner N , et al. 2014
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	15126	P06467	HITS-CLIP	Preitner N , et al. 2014
Hbb-y	hemoglobin Y, beta-like embryonic chain	15135	P02104	HITS-CLIP	Preitner N , et al. 2014
Hdac2	Histone deacetylase 2	15182	P70288	HITS-CLIP	Preitner N , et al. 2014
HGS	hepatocyte growth factor-regulated tyrosine kinase substrate	9146	O14964	Y2H	Bandyopadhyay S , et al. 2010
Hipk1	homeodomain interacting protein kinase 1	15257	O88904	HITS-CLIP	Preitner N , et al. 2014
Hmgcr	3-hydroxy-3-methylglutaryl-Coenzyme A reductase	15357	Q01237	HITS-CLIP	Preitner N , et al. 2014
Hn1	"Hematological and neurological expressed 1 protein, N-terminally processed	15374	P97825	HITS-CLIP	Preitner N , et al. 2014
Hnrnpa0	Heterogeneous nuclear ribonucleoprotein A0	77134	Q9CX86	HITS-CLIP	Preitner N , et al. 2014
Hnrnpd	heterogeneous nuclear ribonucleoprotein D	11991	Q60668	HITS-CLIP	Preitner N , et al. 2014
Hnrnpl	heterogeneous nuclear ribonucleoprotein L	15388	Q8R081	HITS-CLIP	Preitner N , et al. 2014
HNRNPM	heterogeneous nuclear ribonucleoprotein M	4670	P52272	Y2H	Bandyopadhyay S , et al. 2010
Hnrnpm	heterogeneous nuclear ribonucleoprotein M	76936	Q9D0E1	HITS-CLIP	Preitner N , et al. 2014
Hnrnpul2	heterogeneous nuclear ribonucleoprotein U-like 2	68693	Q00PI9	HITS-CLIP	Preitner N , et al. 2014
Hsd17b12	hydroxysteroid (17-beta) dehydrogenase 12	56348	O70503	HITS-CLIP	Preitner N , et al. 2014
Hsp90aa1	heat shock protein 90, alpha (cytosolic), class A member 1	15519	P07901	HITS-CLIP	Preitner N , et al. 2014
Hspa4			Q61316	HITS-CLIP	Preitner N , et al. 2014
HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	3309	Q2KHP4	Y2H	Bandyopadhyay S , et al. 2010
Hspa5	heat shock protein 5	14828	P20029	HITS-CLIP	Preitner N , et al. 2014
HSPH1	heat shock 105kDa/110kDa protein 1	10808	Q92598	IP; LC-MS/MS	Yu N , et al. 2015
Id4	inhibitor of DNA binding 4	15904	P41139	HITS-CLIP	Preitner N , et al. 2014
Idh1	isocitrate dehydrogenase 1 (NADP+), soluble	15926	O88844	HITS-CLIP	Preitner N , et al. 2014
Igfbpl1	insulin-like growth factor binding protein-like 1	75426	Q80W15	HITS-CLIP	Preitner N , et al. 2014
Impad1	inositol monophosphatase domain containing 1	242291	Q80V26	HITS-CLIP	Preitner N , et al. 2014
ING5	inhibitor of growth family, member 5	84289	Q8WYH8	Y2H	Bandyopadhyay S , et al. 2010
IQGAP1	IQ motif containing GTPase activating protein 1	8826	P46940	IP/WB; in vitro binding assay	Watanabe T , et al. 2004
Ireb2	iron responsive element binding protein 2	64602	Q811J3	HITS-CLIP	Preitner N , et al. 2014
Irf2bp2	interferon regulatory factor 2 binding protein 2	270110	E9Q1P8	HITS-CLIP	Preitner N , et al. 2014
Islr2	immunoglobulin superfamily containing leucine-rich repeat 2	320563	Q5RKR3	HITS-CLIP	Preitner N , et al. 2014
Ivns1abp	influenza virus NS1A binding protein	117198	Q920Q8	HITS-CLIP	Preitner N , et al. 2014
JUP	junction plakoglobin	3728	P14923	GST; IP/WB	Shibata T , et al. 1994
KIAA1328	KIAA1328	57536	Q86T90	Y2H	Bandyopadhyay S , et al. 2010
KIAA1370	KIAA1370	56204	Q32MH5	Y2H	Bandyopadhyay S , et al. 2010
KIAA1683	KIAA1683	80726	Q9H0B3	IP; LC-MS/MS	Huttlin EL , et al. 2015
Kidins220	kinase D-interacting substrate 220	77480	E9Q9B7	HITS-CLIP	Preitner N , et al. 2014
Kif21a	kinesin family member 21A	16564	Q9QXL2	HITS-CLIP	Preitner N , et al. 2014
KIF5B	kinesin family member 5B	3799	P33176	Y2H	Bandyopadhyay S , et al. 2010
Kif5c	kinesin family member 5C	16574	P28738	HITS-CLIP	Preitner N , et al. 2014
KIFAP3	kinesin-associated protein 3	22920	Q92845	in vitro binding assay; Y2H; IP/WB	Jimbo T , et al. 2002
Klhdc10	kelch domain containing 10	76788	Q6PAR0	HITS-CLIP	Preitner N , et al. 2014
Klhl9	kelch-like 9	242521	Q6ZPT1	HITS-CLIP	Preitner N , et al. 2014
Kmt2d			Q6PDK2	HITS-CLIP	Preitner N , et al. 2014
Kpnb1	karyopherin (importin) beta 1	16211	P70168	HITS-CLIP	Preitner N , et al. 2014
KRT13	keratin 13	3860	P13646	Y2H	Bandyopadhyay S , et al. 2010
KRT14	keratin 14	3861	P02533	Y2H	Bandyopadhyay S , et al. 2010
KRT15	keratin 15	3866	P19012	Y2H	Bandyopadhyay S , et al. 2010
KRT17	keratin 17	3872	Q04695	Y2H	Bandyopadhyay S , et al. 2010
KRT19	keratin 19	3880	P08727	Y2H	Bandyopadhyay S , et al. 2010
KRT23	keratin 23 (histone deacetylase inducible)	25984	Q9C075	Y2H	Bandyopadhyay S , et al. 2010
KRT5	keratin 5	3852	P13647	Y2H	Bandyopadhyay S , et al. 2010
LAMA3	laminin, alpha 3	3909	Q16787	Y2H	Bandyopadhyay S , et al. 2010
LAMA4	laminin, alpha 4	3910	Q16363	Y2H	Bandyopadhyay S , et al. 2010
Laptm4a			Q60961	HITS-CLIP	Preitner N , et al. 2014
Lars2	leucyl-tRNA synthetase, mitochondrial	102436	Q8VDC0	HITS-CLIP	Preitner N , et al. 2014
LATS1	LATS, large tumor suppressor, homolog 1 (Drosophila)	9113	O95835	IP/WB	Cai J , et al. 2015
Leng8	leukocyte receptor cluster (LRC) member 8	232798	Q8CBY3	HITS-CLIP	Preitner N , et al. 2014
Lime1	Lck interacting transmembrane adaptor 1	72699	Q9EQR5	HITS-CLIP	Preitner N , et al. 2014
LIN7C	lin-7 homolog C (C. elegans)	55327	Q9NUP9	IP; LC-MS/MS	Huttlin EL , et al. 2015
Lin7c	lin-7 homolog C (C. elegans)	22343	A2ARI2	HITS-CLIP	Preitner N , et al. 2014
Lmnb1	lamin B1	16906	P14733	HITS-CLIP	Preitner N , et al. 2014
LPHN1	latrophilin 1	22859	O94910	Y2H	Bandyopadhyay S , et al. 2010
Lrrc58	leucine rich repeat containing 58	320184	Q3UGP9	HITS-CLIP	Preitner N , et al. 2014
Lrrn1	leucine rich repeat protein 1, neuronal	16979	Q61809	HITS-CLIP	Preitner N , et al. 2014
Luc7l3	LUC7-like 3 (S. cerevisiae)	67684	Q5SUF2	HITS-CLIP	Preitner N , et al. 2014
LZTS2	leucine zipper, putative tumor suppressor 2	84445	Q9BRK4	IP; LC-MS/MS	Huttlin EL , et al. 2015
MACF1	microtubule-actin crosslinking factor 1	23499	Q9UPN3	Y2H	Bandyopadhyay S , et al. 2010
Magee1	melanoma antigen, family E, 1	107528	Q6PCZ4	HITS-CLIP	Preitner N , et al. 2014
Map1b	microtubule-associated protein 1B	17755	P14873	HITS-CLIP	Preitner N , et al. 2014
MAPRE1	microtubule-associated protein, RP/EB family, member 1	22919	Q15691	GST	Askham JM , et al. 2002
Marcks	myristoylated alanine rich protein kinase C substrate	17118	P26645	HITS-CLIP	Preitner N , et al. 2014
Marcksl1	MARCKS-like 1	17357	P28667	HITS-CLIP	Preitner N , et al. 2014
Maz	MYC-associated zinc finger protein (purine-binding transcription factor)	17188	P56671	HITS-CLIP	Preitner N , et al. 2014
MBD5	methyl-CpG binding domain protein 5	55777	Q9P267	Y2H	Bandyopadhyay S , et al. 2010
MCM3AP	minichromosome maintenance complex component 3 associated protein	8888	O60318	Y2H	Bandyopadhyay S , et al. 2010
Mest	mesoderm specific transcript	17294	Q07646	HITS-CLIP	Preitner N , et al. 2014
Mex3d	mex3 homolog D (C. elegans)	237400	E9PUA0	HITS-CLIP	Preitner N , et al. 2014
Midn	midnolin	59090	Q3TPJ7	HITS-CLIP	Preitner N , et al. 2014
Mlec	malectin	109154	Q6ZQI3	HITS-CLIP	Preitner N , et al. 2014
Mllt11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11	56772	P97783	HITS-CLIP	Preitner N , et al. 2014
Mllt6			Q8VHB4	HITS-CLIP	Preitner N , et al. 2014
Mn1	meningioma 1	433938	D3YWE6	HITS-CLIP	Preitner N , et al. 2014
MUC1	mucin 1, cell surface associated	4582	P15941	IP/WB	Hattrup CL , et al. 2004
MYH10	myosin, heavy chain 10, non-muscle	4628	P35580	Y2H	Bandyopadhyay S , et al. 2010
MYH11	myosin, heavy chain 11, smooth muscle	4629	P35749	Y2H	Bandyopadhyay S , et al. 2010
MYO6	myosin VI	4646	Q9UM54	Y2H	Bandyopadhyay S , et al. 2010
Naa38	N(alpha)-acetyltransferase 38, NatC auxiliary subunit	78304	Q9D2U5	HITS-CLIP	Preitner N , et al. 2014
NAV1	neuron navigator 1	89796	Q8NEY1	Y2H	Bandyopadhyay S , et al. 2010
NAV2	neuron navigator 2	89797	Q8IVL1	Y2H	Bandyopadhyay S , et al. 2010
NAV3	neuron navigator 3	89795	Q8IVL0	Y2H	Bandyopadhyay S , et al. 2010
Ncan	neurocan	13004	P55066	HITS-CLIP	Preitner N , et al. 2014
NCKAP5	NCK-associated protein 5	344148	O14513	Y2H	Bandyopadhyay S , et al. 2010
NCKAP5L	NCK-associated protein 5-like	57701	Q9HCH0	Y2H	Bandyopadhyay S , et al. 2010
Ncoa6	nuclear receptor coactivator 6	56406	Q5XJV5	HITS-CLIP	Preitner N , et al. 2014
ND4	mitochondrially encoded NADH dehydrogenase 4	4538	P03905	Y2H	Bandyopadhyay S , et al. 2010
Ndn	necdin	17984	P25233	HITS-CLIP	Preitner N , et al. 2014
NEB	nebulin	4703	P20929	Y2H	Bandyopadhyay S , et al. 2010
Nedd4	neural precursor cell expressed, developmentally down-regulated 4	17999	P46935	HITS-CLIP	Preitner N , et al. 2014
Neto2	neuropilin (NRP) and tolloid (TLL)-like 2	74513	Q8BNJ6	HITS-CLIP	Preitner N , et al. 2014
Neurod6	neurogenic differentiation 6	11922	P48986	HITS-CLIP	Preitner N , et al. 2014
Nnat	neuronatin	18111	Q61979	HITS-CLIP	Preitner N , et al. 2014
NOSTRIN	nitric oxide synthase trafficker	115677	Q8IVI9	Y2H	Bandyopadhyay S , et al. 2010
Npepps	aminopeptidase puromycin sensitive	19155	Q11011	HITS-CLIP	Preitner N , et al. 2014
Nptn	neuroplastin	20320	P97300	HITS-CLIP	Preitner N , et al. 2014
Nr2f1	nuclear receptor subfamily 2, group F, member 1	13865	Q60632	HITS-CLIP	Preitner N , et al. 2014
Nrep	neuronal regeneration related protein	27528	Q07475	HITS-CLIP	Preitner N , et al. 2014
Nsg2	neuron specific gene family member 2	18197	P47759	HITS-CLIP	Preitner N , et al. 2014
Nucks1	nuclear casein kinase and cyclin-dependent kinase substrate 1	98415	Q80XU3	HITS-CLIP	Preitner N , et al. 2014
Nudt3	nudix (nucleotide diphosphate linked moiety X)-type motif 3	56409	Q9JI46	HITS-CLIP	Preitner N , et al. 2014
Nufip2	nuclear fragile X mental retardation protein interacting protein 2	68564	Q5F2E7	HITS-CLIP	Preitner N , et al. 2014
NUP153	nucleoporin 153kDa	9972	P49790	Y2H	Bandyopadhyay S , et al. 2010
NUP214	nucleoporin 214kDa	8021	P35658	Y2H	Bandyopadhyay S , et al. 2010
NUP54	nucleoporin 54kDa	53371	Q7Z3B4	Y2H	Bandyopadhyay S , et al. 2010
NUP98	nucleoporin 98kDa	4928	P52948	Y2H	Bandyopadhyay S , et al. 2010
NUPL1	nucleoporin like 1	9818	Q9BVL2	Y2H	Bandyopadhyay S , et al. 2010
NUPL2	nucleoporin like 2	11097	O15504	Y2H	Bandyopadhyay S , et al. 2010
Ogt	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)	108155	Q8CGY8	HITS-CLIP	Preitner N , et al. 2014
Pafah1b1	platelet-activating factor acetylhydrolase, isoform 1b, subunit 1	18472	P63005	HITS-CLIP	Preitner N , et al. 2014
Pbrm1			Q8BSQ9	HITS-CLIP	Preitner N , et al. 2014
Pcbp1	poly(rC) binding protein 1	23983	P60335	HITS-CLIP	Preitner N , et al. 2014
Pcdhg*	protocadherin gamma subfamily A, 4	93712	Q91XY4	HITS-CLIP	Preitner N , et al. 2014
Pdia6	protein disulfide isomerase associated 6	71853	Q922R8	HITS-CLIP	Preitner N , et al. 2014
Pfn2	profilin 2	18645	Q9JJV2	HITS-CLIP	Preitner N , et al. 2014
Pgrmc1	progesterone receptor membrane component 1	53328	O55022	HITS-CLIP	Preitner N , et al. 2014
Plekhj1	pleckstrin homology domain containing, family J member 1	78670	Q9D240	HITS-CLIP	Preitner N , et al. 2014
PNISR	PNN-interacting serine/arginine-rich protein	25957	Q8TF01	Y2H	Bandyopadhyay S , et al. 2010
Polr2m	polymerase (RNA) II (DNA directed) polypeptide M	28015	Q6P6I6	HITS-CLIP	Preitner N , et al. 2014
POM121	POM121 membrane glycoprotein	9883	Q96HA1	Y2H	Bandyopadhyay S , et al. 2010
POM121C	POM121 membrane glycoprotein C	100101267	A8CG34	Y2H	Bandyopadhyay S , et al. 2010
Pou3f3	POU domain, class 3, transcription factor 3	18993	P31361	HITS-CLIP	Preitner N , et al. 2014
Ppm1b	protein phosphatase 1B, magnesium dependent, beta isoform	19043	P36993	HITS-CLIP	Preitner N , et al. 2014
Ppp1cb	protein phosphatase 1, catalytic subunit, beta isoform	19046	P62141	HITS-CLIP	Preitner N , et al. 2014
PPP1R13B	protein phosphatase 1, regulatory (inhibitor) subunit 13B	23368	Q8WUF5	Y2H	Bandyopadhyay S , et al. 2010
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isoenzyme	5515	P67775	Metabolic labeling with 32P	Ikeda S , et al. 2000
Ppp2ca	protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform	19052	P63330	HITS-CLIP	Preitner N , et al. 2014
Ppp6r1	protein phosphatase 6, regulatory subunit 1	243819	Q7TSI3	HITS-CLIP	Preitner N , et al. 2014
Prkar1a	"cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally p	19084	Q9DBC7	HITS-CLIP	Preitner N , et al. 2014
Prpf4b	PRP4 pre-mRNA processing factor 4 homolog B (yeast)	19134	Q61136	HITS-CLIP	Preitner N , et al. 2014
Prrc2b	proline-rich coiled-coil 2B	227723	Q7TPM1	HITS-CLIP	Preitner N , et al. 2014
PSMD1	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	5707	Q99460	Y2H	Bandyopadhyay S , et al. 2010
PTPN13	protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)	5783	O14603	Y2H; GST; in vitro binding assay; Surface plasmon resonance (SPR)	Erdmann KS , et al. 2000
Pum1	pumilio 1 (Drosophila)	80912	Q80U78	HITS-CLIP	Preitner N , et al. 2014
Qk	quaking	19317	Q9QYS9	HITS-CLIP	Preitner N , et al. 2014
R3hdm4	R3H domain containing 4	109284	Q4VBF2	HITS-CLIP	Preitner N , et al. 2014
Rad23b	RAD23b homolog (S. cerevisiae)	19359	P54728	HITS-CLIP; EMSA	Preitner N , et al. 2014
RANBP2	RAN binding protein 2	5903	P49792	Y2H	Bandyopadhyay S , et al. 2010
RANBP9	RAN binding protein 9	10048	Q96S59	Y2H	Bandyopadhyay S , et al. 2010
Rbbp4	retinoblastoma binding protein 4	19646	Q60972	HITS-CLIP	Preitner N , et al. 2014
Rbfox2	RNA binding protein, fox-1 homolog (C. elegans) 2	93686	Q8BP71	HITS-CLIP	Preitner N , et al. 2014
Rbm33	RNA binding motif protein 33	381626	Q9CXK9	HITS-CLIP	Preitner N , et al. 2014
RBM4B	RNA binding motif protein 4B	83759	Q9BQ04	Y2H	Bandyopadhyay S , et al. 2010
Rc3h2	ring finger and CCCH-type zinc finger domains 2	319817	P0C090	HITS-CLIP	Preitner N , et al. 2014
Rcn2	reticulocalbin 2	26611	Q8BP92	HITS-CLIP	Preitner N , et al. 2014
Rgma	repulsive guidance molecule family member A	244058	Q6PCX7	HITS-CLIP	Preitner N , et al. 2014
Rgmb	RGM domain family, member B	68799	Q7TQ33	HITS-CLIP	Preitner N , et al. 2014
Rimklb	ribosomal modification protein rimK-like family member B	108653	Q80WS1	HITS-CLIP	Preitner N , et al. 2014
Rnd3	Rho family GTPase 3	74194	P61588	HITS-CLIP	Preitner N , et al. 2014
Rnf145	ring finger protein 145	74315	Q5SWK7	HITS-CLIP	Preitner N , et al. 2014
Rnf2	ring finger protein 2	19821	Q9CQJ4	HITS-CLIP	Preitner N , et al. 2014
RP1	retinitis pigmentosa 1 (autosomal dominant)	6101	P56715	IP/WB	Renner C , et al. 1997
RPS27	ribosomal protein S27	6232	P42677	Y2H	Bandyopadhyay S , et al. 2010
Rps6kb1	ribosomal protein S6 kinase, 70kDa, polypeptide 1	72508	Q8BSK8	HITS-CLIP	Preitner N , et al. 2014
Rtn1	reticulon 1	104001	Q8K0T0	HITS-CLIP	Preitner N , et al. 2014
Rtn3	reticulon 3	20168	Q9ES97	HITS-CLIP	Preitner N , et al. 2014
Rtn4	reticulon 4	68585	Q99P72	HITS-CLIP	Preitner N , et al. 2014
SAV1	salvador homolog 1 (Drosophila)	60485	Q9H4B6	IP/WB	Cai J , et al. 2015
Scd2	stearoyl-Coenzyme A desaturase 2	20250	P13011	HITS-CLIP	Preitner N , et al. 2014
Sec23a	SEC23A (S. cerevisiae)	20334	Q01405	HITS-CLIP	Preitner N , et al. 2014
SEC31A	SEC31 homolog A (S. cerevisiae)	22872	O94979	Y2H	Bandyopadhyay S , et al. 2010
Senp6	SUMO/sentrin specific peptidase 6	215351	Q6P7W0	HITS-CLIP	Preitner N , et al. 2014
Serinc1	serine incorporator 1	56442	Q9QZI8	HITS-CLIP	Preitner N , et al. 2014
SETDB1	SET domain, bifurcated 1	9869	Q15047	Y2H	Bandyopadhyay S , et al. 2010
SFN	stratifin	2810	P31947	TAP; MudPIT	Benzinger A , et al. 2005
SIAH1	seven in absentia homolog 1 (Drosophila)	6477	Q8IUQ4	in vitro binding assay; IP/WB	Liu J , et al. 2001
Slc38a1	solute carrier family 38, member 1	105727	Q8K2P7	HITS-CLIP	Preitner N , et al. 2014
Slc38a2	solute carrier family 38, member 2	67760	Q8CFE6	HITS-CLIP	Preitner N , et al. 2014
SMC3	structural maintenance of chromosomes 3	9126	Q9UQE7	Y2H	Bandyopadhyay S , et al. 2010
Smg7	Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)	226517	Q5RJH6	HITS-CLIP	Preitner N , et al. 2014
Snhg11	small nucleolar RNA host gene 11	319317	Q4G0K9	HITS-CLIP	Preitner N , et al. 2014
SNRNP200	small nuclear ribonucleoprotein 200kDa (U5)	23020	O75643	Y2H	Bandyopadhyay S , et al. 2010
Sox11	SRY-box containing gene 11	20666	Q7M6Y2	HITS-CLIP	Preitner N , et al. 2014
Sox4	SRY-box containing gene 4	20677	Q06831	HITS-CLIP	Preitner N , et al. 2014
SPECC1L	sperm antigen with calponin homology and coiled-coil domains 1-like	23384	Q69YQ0	Y2H	Bandyopadhyay S , et al. 2010
SPTBN1	spectrin, beta, non-erythrocytic 1	6711	Q01082	Y2H	Bandyopadhyay S , et al. 2010
Sptbn1	spectrin beta 2	20742	Q62261	HITS-CLIP	Preitner N , et al. 2014
SPTBN2	spectrin, beta, non-erythrocytic 2	6712	O15020	Y2H	Bandyopadhyay S , et al. 2010
Srcin1	SRC kinase signaling inhibitor 1	56013	Q9QWI6	HITS-CLIP	Preitner N , et al. 2014
Srsf1	serine/arginine-rich splicing factor 1	110809	Q6PDM2	HITS-CLIP	Preitner N , et al. 2014
Srsf7	serine/arginine-rich splicing factor 7	225027	Q8BL97	HITS-CLIP	Preitner N , et al. 2014
Srsf9	serine/arginine-rich splicing factor 9	108014	Q9D0B0	HITS-CLIP	Preitner N , et al. 2014
Ssr3	signal sequence receptor, gamma	67437	Q9DCF9	HITS-CLIP	Preitner N , et al. 2014
Stxbp1	syntaxin binding protein 1	20910	O08599	HITS-CLIP	Preitner N , et al. 2014
SYNC	Syncoilin	81493	Q9H7C4-2	IP; LC-MS/MS	Huttlin EL , et al. 2015
Syncrip	synaptotagmin binding, cytoplasmic RNA interacting protein	56403	Q3TRV3	HITS-CLIP	Preitner N , et al. 2014
SYNE1	spectrin repeat containing, nuclear envelope 1	23345	Q8NF91	Y2H	Bandyopadhyay S , et al. 2010
Syt1	synaptotagmin I	20979	P46096	HITS-CLIP	Preitner N , et al. 2014
Syt11	synaptotagmin XI	229521	Q9R0N3	HITS-CLIP	Preitner N , et al. 2014
T2			Q06666	HITS-CLIP	Preitner N , et al. 2014
TAF1	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa	6872	P21675	Y2H	Bandyopadhyay S , et al. 2010
Taok1	TAO kinase 1	216965	Q5F2E8	HITS-CLIP	Preitner N , et al. 2014
Tardbp	TAR DNA binding protein	230908	Q921F2	HITS-CLIP	Preitner N , et al. 2014
Tbc1d16	TBC1 domain family, member 16	207592	Q6PFC0	HITS-CLIP	Preitner N , et al. 2014
Tbr1	T-box brain gene 1	21375	Q64336	HITS-CLIP	Preitner N , et al. 2014
Tcf4	transcription factor 4	21413	Q60722	HITS-CLIP	Preitner N , et al. 2014
TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	7020	P05549	IP/WB; in vitro binding assay; GST	Li Q and Dashwood RH 2004
Tle3	transducin-like enhancer of split 3, homolog of Drosophila E(spl)	21887	Q08122	HITS-CLIP	Preitner N , et al. 2014
Tle4	transducin-like enhancer of split 4, homolog of Drosophila E(spl)	21888	Q62441	HITS-CLIP	Preitner N , et al. 2014
Tm9sf3	transmembrane 9 superfamily member 3	107358	Q9ET30	HITS-CLIP	Preitner N , et al. 2014
Tmed7	transmembrane emp24 protein transport domain containing 7	66676	D3YZZ5	HITS-CLIP	Preitner N , et al. 2014
Tmeff1	transmembrane protein with EGF-like and two follistatin-like domains 1	230157	Q6PFE7	HITS-CLIP	Preitner N , et al. 2014
Tmod2	tropomodulin 2	50876	Q9JKK7	HITS-CLIP	Preitner N , et al. 2014
Tmsb4x	"Hematopoietic system regulatory peptide"	19241	P20065	HITS-CLIP	Preitner N , et al. 2014
Tmx1	thioredoxin-related transmembrane protein 1	72736	Q8VBT0	HITS-CLIP	Preitner N , et al. 2014
Tmx4	thioredoxin-related transmembrane protein 4	52837	Q8C0L0	HITS-CLIP	Preitner N , et al. 2014
Tnks2	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2	74493	Q3UES3	HITS-CLIP	Preitner N , et al. 2014
Tnrc6b	trinucleotide repeat containing 6b	213988	Q8BKI2	HITS-CLIP	Preitner N , et al. 2014
Tomm70a	translocase of outer mitochondrial membrane 70 homolog A (yeast)	28185	Q9CZW5	HITS-CLIP	Preitner N , et al. 2014
Top2b	topoisomerase (DNA) II beta	21974	Q64511	HITS-CLIP	Preitner N , et al. 2014
TOP3B	topoisomerase (DNA) III beta	8940	O95985	HITS-CLIP	Xu D , et al. 2013
TPR	translocated promoter region (to activated MET oncogene)	7175	P12270	Y2H	Bandyopadhyay S , et al. 2010
Tpr	translocated promoter region, nuclear basket protein	108989	F6ZDS4	HITS-CLIP	Preitner N , et al. 2014
TRIM21	tripartite motif-containing 21	6737	P19474	Y2H	Bandyopadhyay S , et al. 2010
Trp53inp1	transformation related protein 53 inducible nuclear protein 1	60599	Q9QXE4	HITS-CLIP	Preitner N , et al. 2014
Tsc22d1	TSC22 domain family, member 1	21807	P62500	HITS-CLIP	Preitner N , et al. 2014
Tspan3	tetraspanin 3	56434	Q545L1	HITS-CLIP	Preitner N , et al. 2014
Ttc14	tetratricopeptide repeat domain 14	67120	Q9CSP9	HITS-CLIP	Preitner N , et al. 2014
Tuba1a	tubulin, alpha 1A	22142	P68369	HITS-CLIP	Preitner N , et al. 2014
Tubb2b	tubulin, beta 2B class IIB	73710	Q9CWF2	HITS-CLIP; EMSA	Preitner N , et al. 2014
Tubb5	tubulin, beta 5 class I	22154	P99024	HITS-CLIP	Preitner N , et al. 2014
UBC	ubiquitin C	7316	P63279	WB; in vitro ubiquitination assay; IP/WB	Choi J , et al. 2004
Ubqln2	ubiquilin 2	54609	Q9QZM0	HITS-CLIP	Preitner N , et al. 2014
Ubxn7	UBX domain protein 7	224111	Q6P5G6	HITS-CLIP	Preitner N , et al. 2014
Ugcg	UDP-glucose ceramide glucosyltransferase	22234	O88693	HITS-CLIP	Preitner N , et al. 2014
Vash1	vasohibin 1	238328	Q8C1W1	HITS-CLIP	Preitner N , et al. 2014
Vcan			Q62059	HITS-CLIP	Preitner N , et al. 2014
Wdr26	WD repeat domain 26	226757	Q8C6G8	HITS-CLIP	Preitner N , et al. 2014
Wsb1	WD repeat and SOCS box-containing 1	78889	O54927	HITS-CLIP	Preitner N , et al. 2014
XPO1	exportin 1 (CRM1 homolog, yeast)	7514	O14980	Affinity chromatography	Tickenbrock L , et al. 2002
Xpr1	xenotropic and polytropic retrovirus receptor 1	19775	Q9Z0U0	HITS-CLIP	Preitner N , et al. 2014
Ywhae	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	22627	P62259	HITS-CLIP	Preitner N , et al. 2014
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	22628	P61982	HITS-CLIP	Preitner N , et al. 2014
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	22631	P63101	HITS-CLIP	Preitner N , et al. 2014
Zfhx3			Q61329	HITS-CLIP	Preitner N , et al. 2014
ZFP106	zinc finger protein 106 homolog (mouse)	64397	Q9H2Y7	Y2H	Bandyopadhyay S , et al. 2010
Zfp26	zinc finger protein 26	22688	P10076	HITS-CLIP	Preitner N , et al. 2014
Zfp516	zinc finger protein 516	329003	Q7TSH3	HITS-CLIP	Preitner N , et al. 2014
Zfp664	zinc finger protein 664	269704	Q4VA44	HITS-CLIP	Preitner N , et al. 2014
Zic1	zinc finger protein of the cerebellum 1	22771	P46684	HITS-CLIP	Preitner N , et al. 2014
ZNF408	zinc finger protein 408	79797	B4DXY4	IP; LC-MS/MS	Huttlin EL , et al. 2015
ZNF785	Zinc finger protein 785	146540	A8K8V0-2	IP; LC-MS/MS	Huttlin EL , et al. 2015
CTNND2	catenin (cadherin associated protein), delta 2	18163	O35927	IP/WB	Bareiss S , et al. 2010
FMR1	fragile X mental retardation 1	14265	P35922	HITS-CLIP	Darnell JC , et al. 2011
Rbfox1	RNA binding protein, fox-1 homolog (C. elegans) 1	268859	Q9JJ43	HITS-CLIP	Weyn-Vanhentenryck SM , et al. 2014
Dlgap1	discs, large (Drosophila) homolog-associated protein 1	65040	P97836	IP/WB	Satoh K , et al. 1997

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Model Summary

References

M_APC_1_CKO_HM

M_APC_2_CKO_HM_THY1-YFP

M_APC_1_CKO_HM

M_APC_2_CKO_HM_THY1-YFP