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construct
M_MECP2_5.2_KO_HT_CORTISONE-L
Model Details
Change
No Change
     
Phenotypic Profile
Category Entity Quantity Experimental Paradigm Age at Testing
Motor phenotype Tremor1
Increased
Description: Abnormal tremor displays earlier onset in females treated with cortisone
Exp Paradigm: General observations in separate cage

General observations 0-10 months
Motor phenotype Clasping reflex1
Increased
Description: Abnormal hindlimb clasping is refractoryto the treatment (significantly earlier onset than one without treatment)
Exp Paradigm: General observations in separate cage

General observations 0-7.5 months
Developmental profile Mortality/lethality1 No change General observations 5.5 months
Not Reported: Circadian sleep/wake cycle,  Communications,  Emotion,  Immune response,  Learning & memory,  Maternal behavior,  Molecular profile,  Neuroanatomy / ultrastructure / cytoarchitecture,  Neurophysiology,  Physiological parameters,  Repetitive behavior,  Seizure,  Sensory,  Social behavior,  
 
References: 1:  Braun S , et al. 2011
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