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Z_MECP2_1_KD_MO_SEMA5B
Model Details
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Phenotypic Profile
Category
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Quantity
Experimental Paradigm
Age at Testing
Neuroanatomy / Ultrastructure / Cytoarchitecture
Dendritic architecture: dendritic length
1
Ameliorated
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Description:
Co-injection of sema5b mRNA ameliorated (67%) the reduction in the total axonal projection length from trigeminal ganglia neurons in mecp2 MO morphants.
Immunofluorescence staining
24 hpf
Description:
Co-injection of sema5b mRNA ameliorated (67%) the reduction in the total axonal projection length from trigeminal ganglia neurons in mecp2 MO morphants.
Not Reported:
Circadian sleep/wake cycle
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Communications
,
Developmental profile
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Emotion
,
Immune response
,
Learning & memory
,
Maternal behavior
,
Molecular profile
,
Motor phenotype
,
Neurophysiology
,
Physiological parameters
,
Repetitive behavior
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Seizure
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Sensory
,
Social behavior
,
References:
1:
Leong WY , et al. 2016
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