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construct
M_MECP2_7_KI_HE_S80A
Model Details
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Phenotypic Profile
Category Entity Quantity Experimental Paradigm Age at Testing
Motor phenotype General locomotor activity1
Decreased
Description: Decreased locomotor activity
Exp Paradigm: Dark cycle running wheel analysis

Running wheel test Unreported
Developmental profile Size/growth1
Increased
Description: Increased average body weight
Exp Paradigm: General observations

General observations Unreported
Molecular profile Transcriptome diversity1
Abnormal
Description: Increased expression of rab3b, vamp3, igsf4b genes;
Exp Paradigm: Gene expression profile

Western blot Unreported
Not Reported: Circadian sleep/wake cycle,  Communications,  Emotion,  Immune response,  Learning & memory,  Maternal behavior,  Neuroanatomy / ultrastructure / cytoarchitecture,  Neurophysiology,  Physiological parameters,  Repetitive behavior,  Seizure,  Sensory,  Social behavior,  
 
References: 1:  Tao J , et al. 2009
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