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M_MECP2_7_KI_HE_S80A
Model Details
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Phenotypic Profile
Category
Entity
Quantity
Experimental Paradigm
Age at Testing
Motor phenotype
General locomotor activity
1
Decreased
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Description:
Decreased locomotor activity
Exp Paradigm:
Dark cycle running wheel analysis
Running wheel test
Unreported
Description:
Decreased locomotor activity
Exp Paradigm:
Dark cycle running wheel analysis
Developmental profile
Size/growth
1
Increased
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Description:
Increased average body weight
Exp Paradigm:
General observations
General observations
Unreported
Description:
Increased average body weight
Exp Paradigm:
General observations
Molecular profile
Transcriptome diversity
1
Abnormal
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Description:
Increased expression of rab3b, vamp3, igsf4b genes;
Exp Paradigm:
Gene expression profile
Western blot
Unreported
Description:
Increased expression of rab3b, vamp3, igsf4b genes;
Exp Paradigm:
Gene expression profile
Not Reported:
Circadian sleep/wake cycle
,
Communications
,
Emotion
,
Immune response
,
Learning & memory
,
Maternal behavior
,
Neuroanatomy / ultrastructure / cytoarchitecture
,
Neurophysiology
,
Physiological parameters
,
Repetitive behavior
,
Seizure
,
Sensory
,
Social behavior
,
References:
1:
Tao J , et al. 2009
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