HELP
Sign In
Quick Links
MindSpec
AutDB Home
Human Gene
Animal Models
PIN
CNV
Reading Room
TOOLS
Advanced Search
User guide
Submit New Gene
Workspace
Pending Updates
M_MECP2_53_KO_HE_REINSTATEMENT-ADVILLIN
Model Details
Change
No Change
Phenotypic Profile
Category
Entity
Quantity
Experimental Paradigm
Age at Testing
Neuroanatomy / Ultrastructure / Cytoarchitecture
Neuronal number: interneurons
1
Restored
View More
Description:
Advillin-cre mediated reinstatement of mecp2 expression restored parvalbumin expression to control levels in the primary somatosensory cortex and in the basolateral amygdala in mutants.
Exp Paradigm:
Primary somatosensory cortex, primary visual cortex
Immunohistochemistry
Adult
Description:
Advillin-cre mediated reinstatement of mecp2 expression restored parvalbumin expression to control levels in the primary somatosensory cortex and in the basolateral amygdala in mutants.
Exp Paradigm:
Primary somatosensory cortex, primary visual cortex
Neuroanatomy / Ultrastructure / Cytoarchitecture
Neuronal number: interneurons
1
Refractory
View More
Description:
Advillin-cre mediated reinstatement of mecp2 expression did not change parvalbumin expression in the primary visual cortex in mutants.
Exp Paradigm:
Primary somatosensory cortex, primary visual cortex
Immunohistochemistry
Adult
Description:
Advillin-cre mediated reinstatement of mecp2 expression did not change parvalbumin expression in the primary visual cortex in mutants.
Exp Paradigm:
Primary somatosensory cortex, primary visual cortex
Not Reported:
Circadian sleep/wake cycle
,
Communications
,
Developmental profile
,
Emotion
,
Immune response
,
Learning & memory
,
Maternal behavior
,
Molecular profile
,
Motor phenotype
,
Neurophysiology
,
Physiological parameters
,
Repetitive behavior
,
Seizure
,
Sensory
,
Social behavior
,
References:
1:
Orefice LL , et al. 2019
HELP
Copyright © 2017 MindSpec, Inc.
