| Phenotypic Profile |
| Category |
Entity |
Quantity |
Experimental Paradigm |
Age at Testing |
| Social behavior |
Social transmission of food preference1 |
Decreased
Description: Mutants failed to acquire the food preference of another mouse following 30 min co-housing.
Exp Paradigm: NA
|
Social transmission of food preference |
3-18 weeks |
| |
|
Description: Mutants failed to acquire the food preference of another mouse following 30 min co-housing.
Exp Paradigm: NA |
|
|
| Social behavior |
Social memory1 |
Decreased
Description: Male mutants show no preference for an unfamiliar mouse over a familiar mouse.
Exp Paradigm: NA
|
Three-chamber social approach test |
3-18 weeks |
| |
|
Description: Male mutants show no preference for an unfamiliar mouse over a familiar mouse.
Exp Paradigm: NA |
|
|
| Emotion |
Anxiety1 |
Increased
Description: Mutants spent less time in the open arms.
Exp Paradigm: NA
|
Elevated plus maze test |
3-18 weeks |
| |
|
Description: Mutants spent less time in the open arms.
Exp Paradigm: NA |
|
|
| Learning & memory |
Object recognition memory1 |
Decreased
Description: Mutants spent less time playing with a novel object.
Exp Paradigm: NA
|
Novel object recognition test |
3-18 weeks |
| |
|
Description: Mutants spent less time playing with a novel object.
Exp Paradigm: NA |
|
|
| Emotion |
Depression1 |
No change |
Tail suspension test |
3-18 weeks |
| Motor phenotype |
General locomotor activity: ambulatory activity1 |
No change |
Open field test |
3-18 weeks |
| Repetitive behavior |
Self grooming: perseveration1 |
No change |
Grooming behavior assessments |
3-18 weeks |
| Social behavior |
Social approach1 |
No change |
Three-chamber social approach test |
3-18 weeks |
|
| Not Reported: |
Circadian sleep/wake cycle, Communications, Developmental profile, Immune response, Maternal behavior, Molecular profile, Neuroanatomy / ultrastructure / cytoarchitecture, Neurophysiology, Physiological parameters, Seizure, Sensory, |
