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Animal Model >> null >> M_MECP2_53_KO_HE_REINSTATEMENT-ADVILLIN Construct Details |
| Model Details :M_MECP2_53_KO_HE_REINSTATEMENT-ADVILLIN
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Model Type |
RESCUE-Genetic
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Model Genotype |
Hemizygous
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Mutation |
Mecp2^STOP/y; Advillin-Cre mice are generated by crossing mice possessing loxP-flanked STOP cassette in intron 2 of the Mecp2 gene on the X chromosome with Advillin-Cre mice to reinstate the expression of Mecp2 in all DRG, trigeminal, and sympathetic ganglia neurons. |
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Allele Type |
Knockout |
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Strain of Origin |
Not specified |
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Genetic Background |
C57BL/6J*129/SvEv*CD1 |
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ES Cell Line |
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Mutant ES Cell Line |
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Model Source |
Jackson Laboratory; RRID:IMSR_JAX:006849 |
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Reference |
Orefice LL , et al. 2019
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