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Animal Model >> null >> M_MECP2_1.3_KO_HE Construct Details |
| Model Details :M_MECP2_1.3_KO_HE
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Model Type |
Genetic
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Model Genotype |
Hemizygous
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Mutation |
Targeting construct deletion of exon 3, which encodes most of the methyl-CpG-binding domain using the cre-loxP recombination system (Mecp2tm1.1Jae/y mice). |
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Allele Type |
Knockout |
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Strain of Origin |
129/Sv |
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Genetic Background |
C57Bl/6J |
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ES Cell Line |
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Mutant ES Cell Line |
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Model Source |
Jaenisch laboratory, MIT (PMID 11242118) |
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Reference |
Johnson RA , et al. 2011,
Schaevitz LR , et al. 2012,
Na ES , et al. 2017
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