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Animal Model >> null >> M_MECP2_1.3_CKO_HE Construct Details |
| Model Details :M_MECP2_1.3_CKO_HE
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Model Type |
Genetic
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Model Genotype |
Homozygous
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Mutation |
Conditional deletion of exon 3 which encodes most of the methyl-CpG-binding domain of the Mecp2 gene using PET1-cre, in serotonergic neurons starting E10 and persisting through adulthood, in male mice |
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Allele Type |
Conditional loss-of-function |
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Strain of Origin |
C56BL/6J |
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Genetic Background |
Not Specified |
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ES Cell Line |
Not Specified |
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Mutant ES Cell Line |
Not Specified |
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Model Source |
Not Specified |
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Reference |
Samaco RC , et al. 2009
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