Curation
Content of the Animal Model module originates entirely from published, peer-reviewed scientific literature and is manually annotated by expert biologists. A comprehensive collection of mouse models was initially compiled from a search of scientific literature using the PubMed database at NCBI.
The challenge in developing an annotation strategy for ASD animal models is to include necessary and sufficient data fields that capture various attributes of the animal model, encompass various types of constructs, and include the wide spectrum of phenotypes reported about ASD in the scientific literature. A schematic representation of the different components that form the Animal Model module is shown in Figure 1