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No Human Gene Data Available
Chromosome
CNV Locus
CNV Type
# of studies
Animal Model
6
Deletion-Duplication
 48
 

No Animal Model Data Available


Interactor Symbol Interactor Name Interactor Organism Entrez ID Uniprot ID Interaction Type Evidence Reference
5-Sep septin 5 5413 Q99719 Y2H; IP/WB; in vitro ubiquitination assay
Choi P , et al. 2003
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 25 P00519 GST; IP/WB; in vitro kinase assay; 2-D gel electrophoresis; MS; WB
Ko HS , et al. 2010
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 7965 Q13155 Y2H; IP/WB; in vitro ubiquitination assay
Corti O , et al. 2003
AURKA aurora kinase A 6790 O14965 In vivo ubiquitination assay; IP/WB
Lee SB , et al. 2015
AURKB aurora kinase B 9212 Q96GD4 In vivo ubiquitination assay
Lee SB , et al. 2015
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 571 O14867 IP/WB
Zenke-Kawasaki Y , et al. 2007
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 8424 O75936 IP; LC-MS/MS
Huttlin EL , et al. 2015
CASP1 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) 834 P43527 WB
Kahns S , et al. 2003
CASP8 caspase 8, apoptosis-related cysteine peptidase 841 Q14790 WB
Kahns S , et al. 2003
CCNB1 cyclin B1 891 P14635 In vivo ubiquitination assay; in vitro ubiquitination assay
Lee SB , et al. 2015
CCNE1 cyclin E1 898 P24864 Nickel-agarose pull-down; in vitro ubiquitination assay
Staropoli JF , et al. 2003
CCT2 chaperonin containing TCP1, subunit 2 (beta) 10576 P78371 IP/WB; Size-exclusion chromatography (SEC)
Imai Y , et al. 2003
CDC20 cell division cycle 20 991 Q12834 in vitro binding assay; IP/WB
Lee SB , et al. 2015
CDK5 cyclin-dependent kinase 5 1020 Q00535 Metabolic labeling with 32P; WB; IP/WB
Avraham E , et al. 2007
CRX cone-rod homeobox 1406 O43186 Y2H
Corominas R , et al. 2014
CUL1 cullin 1 8454 Q13616 IP/WB; GST; Nickel-agarose pull-down
Staropoli JF , et al. 2003
DLX2 distal-less homeobox 2 1746 Q07687 Y2H
Corominas R , et al. 2014
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 3301 P31689 IP/WB
Imai Y , et al. 2002
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 3337 P25685 IP/WB
Imai Y , et al. 2002
DRP1 Dynamin-1-like protein 10059 O00429 IP/WB; Immunofluorescence ; in vitro ubiquitination assay
Wang H , et al. 2011
FAM46C family with sequence similarity 46, member C 54855 Q5VWP2 Y2H
Corominas R , et al. 2014
FANCA Fanconi anemia, complementation group A 2175 O15360 IP/WB
Sumpter R Jr , et al. 2016
FANCC Fanconi anemia, complementation group C 2176 Q00597 IP/WB; Co-localization
Sumpter R Jr , et al. 2016
FBXW7 F-box and WD repeat domain containing 7 55294 Q969H0 IP/WB; GST
Staropoli JF , et al. 2003
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 51024 Q9Y3D6 IP/WB; Immunofluorescence ; in vitro ubiquitination assay
Cui M , et al. 2010
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 51343 Q9UM11 in vitro binding assay; IP/WB
Lee SB , et al. 2015
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) 2861 O15354 IP/WB; WB; in vitro ubiquitination assay
Y2H; IP/WB; in vitro ubiquitination assay
Imai Y , et al. 2001
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) 2861 O15354 Imai Y , et al. 2002
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) 2861 O15354 Dutta P , et al. 2014
HEXDC hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing 284004 Q8WVB3 Y2H
Stelzl U , et al. 2005
HSPA1A heat shock 70kDa protein 1A 3303 P08107 IP; LC-MS/MS; IP/WB
Imai Y , et al. 2002
HSPA1A heat shock 70kDa protein 1A 3303 P08107 IP/WB; Size-exclusion chromatography (SEC)
Imai Y , et al. 2003
HSPA4 heat shock 70kDa protein 4 3308 P34932 IP/WB
Imai Y , et al. 2002
HSPA8 heat shock 70kDa protein 8 3312 P11142 IP/WB
Imai Y , et al. 2002
LIMK1 LIM domain kinase 1 3984 P53667 IP/WB; in vitro ubiquitination assay
Lim MK , et al. 2007
LRRK2 leucine-rich repeat kinase 2 120892 Q5S007 IP/WB
Smith WW , et al. 2005
MAPT microtubule-associated protein tau 4137 P10636 IP/WB
Petrucelli L , et al. 2004
MEOX1 mesenchyme homeobox 1 4222 P50221 Y2H
Corominas R , et al. 2014
MEOX2 Homeobox protein MOX-2 4223 P50222 Y2H
Corominas R , et al. 2014
MFN1 mitofusin 1 55669 Q8IWA4 IP/WB; Immunofluorescence ; in vitro ubiquitination assay
Tanaka A , et al. 2010
MFN2 mitofusin 2 9927 O95140 IP/WB; Immunofluorescence ; in vitro ubiquitination assay
Tanaka A , et al. 2010
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 56901 Q9NRX3 Y2H
Stelzl U , et al. 2005
NEK2 NIMA-related kinase 2 4751 P51955 In vivo ubiquitination assay; in vitro ubiquitination assay
Lee SB , et al. 2015
PACRG PARK2 co-regulated 135138 Q96M98 IP/WB; Co-localization; Size-exclusion chromatography (SEC)
Imai Y , et al. 2003
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) 5049 P68402 Y2H
Stelzl U , et al. 2005
PARK2 parkinson protein 2, E3 ubiquitin protein ligase (parkin) 5071 O60260 in vitro ubiquitination assay
Hampe C , et al. 2006
PARK7 Parkinson disease (autosomal recessive, early onset) 7 11315 Q99497 IP/WB
Moore DJ , et al. 2004
PASK PAS domain containing serine/threonine kinase 23178 Q96RG2 IP; LC-MS/MS
Huttlin EL , et al. 2015
PCYT2 phosphate cytidylyltransferase 2, ethanolamine 5833 Q99447 IP; LC-MS/MS
Huttlin EL , et al. 2015
PDCD2 programmed cell death 2 5134 Q16342 IP/WB; in vitro ubiquitination assay
Fukae J , et al. 2009
PINK1 PTEN induced putative kinase 1 65018 Q9BXM7 IP/WB; Affinity chromatography
Shiba K , et al. 2009
PLCG1 phospholipase C, gamma 1 5335 P19174 IP/WB
Dehvari N , et al. 2008
PLK1 polo-like kinase 1 5347 P53350 In vivo ubiquitination assay; IP/WB; in vitro kinase assay; in vivo kinase assay; Co-localization
Lee SB , et al. 2015
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 5682 P25786 IP/WB
Imai Y , et al. 2002
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 5685 P25789 Y2H; IP/WB
Dchsel JC , et al. 2005
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 5705 P62195 IP/WB
Tsai YC , et al. 2003
PTTG1 pituitary tumor-transforming 1 9232 O95997 In vivo ubiquitination assay; in vitro ubiquitination assay
Lee SB , et al. 2015
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 5879 P63000 Y2H
Stelzl U , et al. 2005
RAD1 RAD1 homolog (S. pombe) 5810 O60671 Y2H
Stelzl U , et al. 2005
RANBP2 RAN binding protein 2 5903 P49792 Y2H; IP/WB; GST; in vitro ubiquitination assay
Um JW , et al. 2005
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 10616 Q9BYM8 Y2H
Corominas R , et al. 2014
REL v-rel reticuloendotheliosis viral oncogene homolog (avian) 5966 Q04864 Y2H
Corominas R , et al. 2014
RGS2 regulator of G-protein signaling 2, 24kDa 5997 P41220 Y2H
Stelzl U , et al. 2005
RNF41 ring finger protein 41 10193 Q9H4P4 Y2H; in vitro binding assay; IP/WB
Zhong L , et al. 2005
SEPT5 septin 5 5413 Q99719 Y2H
Corominas R , et al. 2014
SIM2 single-minded homolog 2 (Drosophila) 6493 Q14190 IP/WB
Okui M , et al. 2005
SLC6A3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 6531 Q01959 Biotinylation assay; IP/WB
IP/WB; WB
Jiang H , et al. 2004
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 13162 Q61327 Biotinylation assay; IP/WB
IP/WB; WB
Jiang H , et al. 2004
SNCA synuclein, alpha (non A4 component of amyloid precursor) 6622 P37840 IP/WB
Choi P , et al. 2001
SNCAIP synuclein, alpha interacting protein 9627 Q9Y6H5 IP/WB; WB; in vitro ubiquitination assay
Chung KK , et al. 2001
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 10273 Q9UNE7 IP/WB
IP; LC-MS/MS; IP/WB; Co-localization; in vitro binding assay
Imai Y , et al. 2002
SYT11 synaptotagmin XI 23208 Q9BT88 Y2H; IP/WB; WB
Huynh DP , et al. 2003
TCF4 transcription factor 4 6925 B3KVA4 Y2H
Corominas R , et al. 2014
TCP1 t-complex 1 6950 P17987 IP/WB; Size-exclusion chromatography (SEC)
Imai Y , et al. 2003
TNFRSF17 Tumor necrosis factor receptor superfamily member 17 608 Q02223 IP; LC-MS/MS
Huttlin EL , et al. 2015
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) 9804 Q15388 In vivo ubiquitination assay
Lee SB , et al. 2015
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) 9804 Q15388 IP/WB
Sumpter R Jr , et al. 2016
TRIP13 thyroid hormone receptor interactor 13 9319 Q15645 Y2H
Rual JF , et al. 2005
TRIP13 thyroid hormone receptor interactor 13 9319 Q15645 Y2H
Corominas R , et al. 2014
UBC ubiquitin C 7316 P63279 IP/WB
Sriram SR , et al. 2005
UBE2G1 ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) 7326 P62253 IP/WB
Imai Y , et al. 2001
UBE2J1 ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast) 51465 Q9Y385 IP/WB
Imai Y , et al. 2001
UBE2L3 ubiquitin-conjugating enzyme E2L 3 7332 P68036 IP/WB
Shimura H , et al. 2000
UBE2L3 ubiquitin-conjugating enzyme E2L 3 7332 P68036 IP/WB
Lee SB , et al. 2015
UBE2L6 ubiquitin-conjugating enzyme E2L 6 9246 O14933 IP/WB
Zhang Y , et al. 2000
VCP valosin containing protein 7415 P55072 IP; LC-MS/MS
Huttlin EL , et al. 2015
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide 7533 Q04917 IP/WB
Sato S , et al. 2005
Dlg1 discs, large homolog 1 (Drosophila) 13383 Q811D0 FRAP
Stiffler MA , et al. 2006
Ptpn5 protein tyrosine phosphatase, non-receptor type 5 19259 P54830 IP/WB; in vitro ubiquitination assay
Kurup PK , et al. 2015
Rgs3 regulator of G-protein signaling 3 50780 Q9DC04 Protein microarray; FRAP
Stiffler MA , et al. 2006
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 25400 P11275 IP/WB
Fallon L , et al. 2001
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 29647 Q62915 GST; IP/WB
Fallon L , et al. 2001
Dlg4 discs, large homolog 4 (Drosophila) 29495 P31016 IP/WB
Fallon L , et al. 2001
Egfr epidermal growth factor receptor 13649 Q01279 IP/WB
Fallon L , et al. 2006
EPS15 epidermal growth factor receptor pathway substrate 15 13858 P42567 GST; in vitro ubiquitination assay; Nickel-agarose pull-down
Fallon L , et al. 2006
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 24410 Q00960 IP/WB
Fallon L , et al. 2001
HOMER1 homer homolog 1 (Drosophila) 29456 Q9Z214 IP/WB
Fallon L , et al. 2001
LOC656767 serine/threonine-protein kinase PINK1, mitochondrial 656767 D6WMX4 in vitro kinase assay; in vitro binding assay
Norkett R , et al. 2015
SNCA synuclein, alpha (non A4 component of amyloid precursor) 6622 P37840 IP/WB
Norris KL , et al. 2015
TUBA1A tubulin, alpha 1A 7846 Q71U36 IP/WB; WB
Ren Y , et al. 2003
TUBB tubulin, beta 203068 P07437 IP/WB; WB
Ren Y , et al. 2003
TUBG1 tubulin, gamma 1 7283 P23258 IP/WB
Zhao J , et al. 2003
UBC ubiquitin C 7316 P63279 UV-cross-linking assay; in vitro binding assay; Size-exclusion chromatography (SEC); Fluoppi assay
Norkett R , et al. 2015
Ube2l3 ubiquitin-conjugating enzyme E2L 3 363836 B2RZA9 ITC; NMR spectroscopy
Sauv V , et al. 2015
eIF-4E Eukaryotic initiation factor 4E 45525 P48598 IP/WB
Ottone C , et al. 2010

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